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Shamanova A.Yu.

Chelyabinsk Regional Clinical Center for Oncology and Nuclear Medicine;
South Ural State Medical University of the Ministry of Health of Russia

Rostovtsev D.M.

Polenov Russian Neurosurgery Institute — Branch of the Almazov National Medical Research Center

Privalov A.V.

Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine;
South-Ural State Medical University

Yarina L.V.

Chelyabinsk Regional Clinical Center for Oncology and Nuclear Medicine;
South Ural State Medical University of the Ministry of Health of Russia

Aristarkhova K.S.

Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine

Sychugov G.V.

Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine;
South-Ural State Medical University

Vasil’kova I.V.

Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine

Artemyeva A.S.

N.N. Petrov National Medical Research Center for Oncology

Saevets V.V.

Chelyabinsk Regional Clinical Center for Oncology and Nuclear Medicine;
South Ural State Medical University of the Ministry of Health of Russia

Alymov E.A.

Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine

Undifferentiated pancreatic carcinoma with osteoclast-like giant cells

Authors:

Shamanova A.Yu., Rostovtsev D.M., Privalov A.V., Yarina L.V., Aristarkhova K.S., Sychugov G.V., Vasil’kova I.V., Artemyeva A.S., Saevets V.V., Alymov E.A.

More about the authors

Journal: Russian Journal of Archive of Pathology. 2023;85(1): 62‑69

DOI: 10.17116/patol20238501162

Read: 2780 times

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Table of contents

UNDIFFERENTIATED PANCREATIC CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS
UNDIFFERENTIATED PANCREATIC CARCINOMA WITH OSTEOCLAST-LIKE GIANT CELLS

To cite this article:

Shamanova AYu, Rostovtsev DM, Privalov AV, et al. . Undifferentiated pancreatic carcinoma with osteoclast-like giant cells. Russian Journal of Archive of Pathology. 2023;85(1):62‑69. (In Russ.)
https://doi.org/10.17116/patol20238501162

Подписка 2026 Архив патологии (Russian Journal of Archive of Pathology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

In the structure of malignant oncological diseases of the Russian population, pancreatic cancer (PCa) occupies the 10th place with a high mortality rate in case of late diagnosis, which is primarily due to the minimal clinical manifestations of this pathology and the absence of precancer as a potential substrate for screening. Undifferentiated pancreatic carcinoma with osteoclast-like giant cell (UC-OGC) is a rare histological variant of PCa with discussed bidirectional histogenesis (epithelial and mesenchymal), epithelial-mesenchymal transition in the tumor and variable prognosis depending on the predominant cellular component. A review of the literature reflecting debatable issues of origin, clinical and pathological characteristics and prognosis of UC-OGC, as well as a description of a clinical case is relevant due to the rare occurrence of this tumor in the routine work of pathologists and oncologists.

Keywords:

pancreatic cancer
osteoclast-like giant cells
undifferentiated carcinoma

Authors:

Shamanova A.Yu.

Chelyabinsk Regional Clinical Center for Oncology and Nuclear Medicine;
South Ural State Medical University of the Ministry of Health of Russia

Rostovtsev D.M.

Polenov Russian Neurosurgery Institute — Branch of the Almazov National Medical Research Center

Privalov A.V.

Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine;
South-Ural State Medical University

Yarina L.V.

Chelyabinsk Regional Clinical Center for Oncology and Nuclear Medicine;
South Ural State Medical University of the Ministry of Health of Russia

Aristarkhova K.S.

Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine

Sychugov G.V.

Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine;
South-Ural State Medical University

Vasil’kova I.V.

Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine

Artemyeva A.S.

N.N. Petrov National Medical Research Center for Oncology

Saevets V.V.

Chelyabinsk Regional Clinical Center for Oncology and Nuclear Medicine;
South Ural State Medical University of the Ministry of Health of Russia

Alymov E.A.

Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine

Received:

11.08.2022

Accepted:

26.10.2022

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