Pathomorphism of rectal cancer during neoadjuvant chemoradiotherapy

Abrosimov A.Iu.; Berdov B.A.; Erygin D.V.; Kondrashova L.M.; Lushnikov E.F.; Nevol'skikh A.A.

doi:https://doi.org/

Abrosimov A.Iu.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr, Moskva

Berdov B.A.

Meditsinskiĭ radiologicheskiĭ nauchnyĭ tsentr RAMN, Obninsk

Erygin D.V.

A.F. Tsyba Medical Radiological Research Centre — Branch of the National Medical Research Center of Radiology of the Ministry of Healthcare of the Russia, Obninsk, Russia

Kondrashova L.M.

FGBU "Meditsinskiĭ radiologicheskiĭ nauchnyĭ tsentr" Minzdrava Rossii, Obninsk

Lushnikov E.F.

FGBU "Meditsinskiĭ radiologicheskiĭ nauchnyĭ tsentr" Minzdrava Rossii, Obninsk

Nevol'skikh A.A.

Meditsinskiĭ radiologicheskiĭ nauchnyĭ tsentr RAMN, Obninsk

Pathomorphism of rectal cancer during neoadjuvant chemoradiotherapy

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Abrosimov A.Iu., Berdov B.A., Erygin D.V., Kondrashova L.M., Lushnikov E.F., Nevol'skikh A.A.

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Journal: Russian Journal of Archive of Pathology. 2013;75(6): 27‑31

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Abrosimov AIu, Berdov BA, Erygin DV, Kondrashova LM, Lushnikov EF, Nevol'skikh AA. Pathomorphism of rectal cancer during neoadjuvant chemoradiotherapy. Russian Journal of Archive of Pathology. 2013;75(6):27‑31. (In Russ.)

Подписка 2026 Архив патологии (Russian Journal of Archive of Pathology)

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Abstract:

The pathomorphism of rectal cancer (RC) was studied in 99 patients who received neoadjuvant chemoradiotherapy using two drugs (5-fluorouracil and xeloda). A morphological study indicated the qualitatively similar manifestations of pathomorphism (tumor necrosis, inflammation, and sclerosis) which were more pronounced in the use of xeloda. Three degrees of the pathomorphism of RC have been identified: the tumor was unchanged, changed, and undetectable.

Keywords:

rectal cancer

neoadjuvant chemoradiotherapy

pathomorphism

Authors:

Abrosimov A.Iu.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr, Moskva

Berdov B.A.

Meditsinskiĭ radiologicheskiĭ nauchnyĭ tsentr RAMN, Obninsk

Erygin D.V.

A.F. Tsyba Medical Radiological Research Centre — Branch of the National Medical Research Center of Radiology of the Ministry of Healthcare of the Russia, Obninsk, Russia

Kondrashova L.M.

FGBU "Meditsinskiĭ radiologicheskiĭ nauchnyĭ tsentr" Minzdrava Rossii, Obninsk

Lushnikov E.F.

FGBU "Meditsinskiĭ radiologicheskiĭ nauchnyĭ tsentr" Minzdrava Rossii, Obninsk

Nevol'skikh A.A.

Meditsinskiĭ radiologicheskiĭ nauchnyĭ tsentr RAMN, Obninsk

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