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Savelenok M.I.

Pirogov Russian National Research Medical University of the Ministry of Health of Russia, Moscow, Russia;
Regional Clinical Hospital for Emergency Care, Barnaul, Russia

Yaroshetsky A.I.

FGBOU VO «Russian national research medical University named after N.I. Pirogov» of Ministry of health of Russia, Moscow, Russia

Raikin I.D.

Altai State Medical University of the Ministry of Health of Russia, Barnaul, Russia

Konanykhin V.D.

Pirogov Russian National Research Medical University of the Ministry of Health of Russia, Moscow, Russia

Zakharchenko I.A.

Regional Clinical Hospital for Emergency Care, Barnaul, Russia

Personalized Airway Pressure Release Ventilation for acute respiratory distress syndrome: pathophysiological rationale, clinical trials and application prospects

Authors:

Savelenok M.I., Yaroshetsky A.I., Raikin I.D., Konanykhin V.D., Zakharchenko I.A.

More about the authors

Journal: Russian Journal of Anesthesiology and Reanimatology. 2019;(6): 52‑64

DOI: 10.17116/anaesthesiology201906152

Read: 12698 times

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Table of contents

PERSONALIZED AIRWAY PRESSURE RELEASE VENTILATION FOR ACUTE RESPIRATORY DISTRESS SYNDROME: PATHOPHYSIOLOGICAL RATIONALE, CLINICAL TRIALS AND APPLICATION PROSPECTS
PERSONALIZED AIRWAY PRESSURE RELEASE VENTILATION FOR ACUTE RESPIRATORY DISTRESS SYNDROME: PATHOPHYSIOLOGICAL RATIONALE, CLINICAL TRIALS AND APPLICATION PROSPECTS

To cite this article:

Savelenok MI, Yaroshetsky AI, Raikin ID, Konanykhin VD, Zakharchenko IA. Personalized Airway Pressure Release Ventilation for acute respiratory distress syndrome: pathophysiological rationale, clinical trials and application prospects. Russian Journal of Anesthesiology and Reanimatology. 2019;(6):52‑64. (In Russ.)
https://doi.org/10.17116/anaesthesiology201906152

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Abstract:

Airway pressure release ventilation (APRV) differs from the conventional ventilation modes due to a significant inversion of the inspiratory to expiratory ratio. This mode is recommended for acute respiratory distress syndrome if the «traditional» approach is not effective. In recent years, ventilation strategy with APRV has significantly changed based and new physiological approach was justified. Various modes of APRV, respiratory physiology during ventilation in this mode, its effect on ventilator-induced lung injury and current evidence on the use of APRV for ARDS are reported in the article.

Keywords:

mechanical ventilation
airway pressure release ventilation
APRV
acute respiratory distress syndrome
ventilator-induced lung injury

Authors:

Savelenok M.I.

Pirogov Russian National Research Medical University of the Ministry of Health of Russia, Moscow, Russia;
Regional Clinical Hospital for Emergency Care, Barnaul, Russia

Yaroshetsky A.I.

FGBOU VO «Russian national research medical University named after N.I. Pirogov» of Ministry of health of Russia, Moscow, Russia

Raikin I.D.

Altai State Medical University of the Ministry of Health of Russia, Barnaul, Russia

Konanykhin V.D.

Pirogov Russian National Research Medical University of the Ministry of Health of Russia, Moscow, Russia

Zakharchenko I.A.

Regional Clinical Hospital for Emergency Care, Barnaul, Russia

Close metadata

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