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Grib A.A.

Sechenov First Moscow State Medical University (Sechenov University)

Panina U.V.

Sechenov First Moscow State Medical University (Sechenov University)

Churyukanov M.V.

Sechenov First Moscow State Medical University (Sechenov University);
Petrovsky Russian Scientific Center of Surgery

Effectiveness of acupuncture, transcutaneous electrical nerve stimulation and scrambler-therapy for cancer-related pain

Authors:

Grib A.A., Panina U.V., Churyukanov M.V.

More about the authors

Journal: Russian Journal of Pain. 2024;22(3): 81‑97

Read: 1561 times


To cite this article:

Grib AA, Panina UV, Churyukanov MV. Effectiveness of acupuncture, transcutaneous electrical nerve stimulation and scrambler-therapy for cancer-related pain. Russian Journal of Pain. 2024;22(3):81‑97. (In Russ.)
https://doi.org/10.17116/pain20242203181

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References:

  1. Laird B, Colvin MF. Management of cancer pain: basic principles and neuropathic cancer pain. European Journal of Cancer. 2008;44:1078-1082.
  2. Urch CE, Suzuki R. Pathophysiology of somatic, visceral, and neuropathic cancer pain. In: Sykes N, Bennett MI, Yuan C-S, eds. Clinical Pain Management: Cancer Pain. 2nd edn. 2008. https://doi.org/10.1201/b13440
  3. Gralow J, Tripathy D. Managing metastatic bone pain: the role of bisphosphonates. Journal of Pain & Symptom Management. 2007;33(4):462-472. 
  4. Vallerand AH, Templin T, Hasenau SM, Riley-Doucet C. Factors that aIect functional status in patients with cancer-related pain. Pain. 2007;132(1-2):82-90. 
  5. Vowles KE, McEntee ML, Julnes PS, Frohe T, Ney JP, van der Goes DN. Rates of opioid misuse, abuse, and addiction in chronic pain: a systematic review and data synthesis. Pain. 2015;156(4):569-576.  https://doi.org/10.1097/01.j.pain.0000460357.01998.f1
  6. Sharfstein JM, Olsen Y. Lessons learned from the opioid epidemic. JAMA. 2019;322(9):809-810. Published online August 05, 2019. https://doi.org/10.1001/jama.2019.9794
  7. Wu X, Chung VC, Hui EP, Ziea ET, Ng BF, Ho RS, Tsoi KK, Wong SY, Wu  JC. Effectiveness of acupuncture and related therapies for palliative care of cancer: overview of systematic reviews. Sci Rep. 2015;5:16776. PMID: 26608664; PMCID: PMC4660374. https://doi.org/10.1038/srep16776
  8. Ben-Arye E, Hausner D, Samuels N, Gamus D, Lavie O, Tadmor T, Gressel O, Agbarya A, Attias S, David A, Schiff E. Impact of acupuncture and integrative therapies on chemotherapy-induced peripheral neuropathy: A multicentered, randomized controlled trial. Cancer. 2022;128(20):3641-3652. Epub 2022 Aug 12. PMID: 35960141. https://doi.org/10.1002/cncr.34422
  9. Disselhoff B. TENS — Transkutane Elektrische Nervenstimulation in der onkologischen Schmerztherapie. In: Bernatzky G, Sittl R, Likar R, eds. Schmerzbehandlung in der Palliativmedizin. 3. Auflage, 3rd edn. Springer, Wien; 2012;241-250. (In German).
  10. Melzack R, Wall PD. Pain mechanisms: A new theory. Science. 1965; 150(3699):971-979. 
  11. Marineo G. Untreatable pain resulting from abdominal cancer: new hope from biophysics? JOP. 2003;4(1):1-10. PMID: 12555009.
  12. Congedi S, Spadini S, Di Pede C, et al. Use of scrambler therapy in acute paediatric pain: A case report and review of the literature. Case Rep Pediatr. 2016;2016:6. 
  13. Russo D, Zoratto F, Tirocchi G, Guarda M. Scrambler therapy in the management of somatosensory signs and symptoms related to neuropathic pain: an exploratory and prospective analysis. Acta Biomed. 2018;89(2):180-185. PMID: 29957749; PMCID: PMC6179012. https://doi.org/10.23750/abm.v89i2.5704
  14. Stringer J, Ryder WD, Mackereth PA, Misra V, Wardley AM. A randomised, pragmatic clinical trial of ACUpuncture plus standard care versus standard care alone FOr Chemotherapy Induced peripheral Neuropathy (ACUFOCIN). Eur J Oncol Nurs. 2022;60:102171. Epub 2022 July 11. PMID: 35952460; PMCID: PMC9592667. https://doi.org/10.1016/j.ejon.2022.102171
  15. Cai RL, Shen GM, Wang H, Guan YY. Brain functional connectivity network studies of acupuncture: A systematic review on resting-state fMRI. J Integr Med. 2018;16(1):26-33. 
  16. Seo HS, Son CG, Lee NH, Cho JH. A suggestion on the action mechanisms of acupuncture treatment for controlling chemotherapy-induced peripheral neuropathy. J Kor Med. 2020;41(4):88-99.  https://doi.org/10.13048/jkm.20047
  17. Lai H-C, Lin Y-W, Hsieh C-L. Acupuncture-analgesia-mediated alleviation of central sensitization. Evidence-Based Complementary and Alternative Medicine. 2019;2019:6173412. https://doi.org/10.1155/2019/6173412
  18. Bao T, Goloubeva O, Pelser C, Porter N, Primrose J, Hester L, Sadowska M, Lapidus R, Medeiros M, Lao L, Dorsey SG, Badros AZ. A pilot study of acupuncture in treating bortezomib-induced peripheral neuropathy in patients with multiple myeloma. Integr Cancer Ther. 2014;13(5):396-404. Epub 2014 May 26. PMID: 24867959; PMCID: PMC4562796. https://doi.org/10.1177/1534735414534729
  19. Molassiotis A, Suen LKP, Cheng HL, Mok TSK, Lee SCY, Wang CH, Lee P, Leung H, Chan V, Lau TKH, Yeo W. A Randomized Assessor-Blinded Wait-List-Controlled Trial to Assess the Effectiveness of Acupuncture in the Management of Chemotherapy-Induced Peripheral Neuropathy. Integr Cancer Ther. 2019;18:1534735419836501. PMID: 30905173; PMCID: PMC6434440. https://doi.org/10.1177/1534735419836501
  20. Dong B, Lin L, Chen Q, Qi Y, Wang F, Qian K, Tian L. Wrist-ankle acupuncture has a positive effect on cancer pain: A meta-analysis. BMC Complement Med Ther. 2021;21(1):24. PMID: 33413347; PMCID: PMC7791657. https://doi.org/10.1186/s12906-020-03193-y
  21. Xu Z, Wang X, Wu Y, Wang C, Fang X. The effectiveness and safety of acupuncture for chemotherapy-induced peripheral neuropathy: A systematic review and meta-analysis. Front Neurol. 2022;13:963358. Published 2022 Oct 03.  https://doi.org/10.3389/fneur.2022.963358
  22. Garcia MK, Cohen L, Guo Y, Zhou Y, You B, Chiang J, Orlowski RZ, Weber D, Shah J, Alexanian R, Thomas S, Romaguera J, Zhang L, Badillo M, Chen Y, Wei Q, Lee R, Delasalle K, Green V, Wang M. Electroacupuncture for thalidomide/bortezomib-induced peripheral neuropathy in multiple myeloma: a feasibility study. J Hematol Oncol. 2014;7:41. PMID: 24886772; PMCID: PMC4038108. Published 2014 May 09.  https://doi.org/10.1186/1756-8722-7-41
  23. Franconi G, Manni L, Schröder S, Marchetti P, Robinson N. A systematic review of experimental and clinical acupuncture in chemotherapy-induced peripheral neuropathy. Evid Based Complement Alternat Med. 2013;2013: 516916. https://doi.org/10.1155/2013/516916
  24. Li K, Giustini D, Seely D. A systematic review of acupuncture for chemotherapy-induced peripheral neuropathy. Curr Oncol. 2019;26(2):e147-e154. PMID: 31043820; PMCID: PMC6476456. Published online 2019 Apr 01.  https://doi.org/10.3747/co.26.4261
  25. Zhi WI, Ingram E, Li SQ, Chen P, Piulson L, Bao T. Acupuncture for Bortezomib-Induced Peripheral Neuropathy: Not Just for Pain. Integr Cancer Ther. 2018;17(4):1079-1086. https://doi.org/10.1177/1534735418788667
  26. Xu L-P, Yang S-L, Su S-Q, Huang B-X, Lan X-M, Yao R-J. Effect of wrist-ankle acupuncture therapy combined with auricular acupuncture on cancer pain: A four-parallel arm randomized controlled trial. Complement Ther Clin Pract. 2020;39:101170. Epub 2020 Apr 08. PMID: 32379695. https://doi.org/10.1016/j.ctcp.2020.101170
  27. Paley CA, Johnson MI, Tashani OA, Bagnall AM. Acupuncture for cancer pain in adults. Cochrane Database Syst Rev. 2015;2015(10):CD007753. PMID: 26468973; PMCID: PMC6513493. https://doi.org/10.1002/14651858.CD007753.pub3
  28. Ben-Arye E, Segev Y, Galil G, Marom I, Gressel O, Stein N, Hirsh I, Samuels N, Schmidt M, Schiff E, Lurie I, Lavie O. Acupuncture during gynecological oncology surgery: A randomized controlled trial assessing the impact of integrative therapies on perioperative pain and anxiety. Cancer. 2023;129(6):908-919. PMID: 36647622. First published: 17 January 2023. https://doi.org/10.1002/cncr.34542
  29. Wang J, Lei Y, Bao B, Yu X, Dai H, Chen F, Li H, Wang B. Acupuncture for pain caused by prostate cancer: Protocol for a systematic review. Medicine (Baltimore). 2019;98(2):e13954. PMID: 30633174; PMCID: PMC6336609. Published online 2019 Jan 11.  https://doi.org/10.1097/MD.0000000000013954
  30. Bao T, Seidman AD, Piulson L, Vertosick E, Chen X, Vickers AJ, Blinder VS, Zhi WI, Li Q, Vahdat LT, Dickler MN, Robson ME, Mao JJ. A phase IIA trial of acupuncture to reduce chemotherapy-induced peripheral neuropathy severity during neoadjuvant or adjuvant weekly paclitaxel chemotherapy in breast cancer patients. Eur J Cancer. 2018;101:12-19. Epub 2018 July 13. PMID: 30007894; PMCID: PMC6147260. https://doi.org/10.1016/j.ejca.2018.06.008
  31. Li C, Zhao C, Zhao J, Wang M, Luo F, Zhou J. Global research trends of acupuncture therapy on cancer pain: A bibliometric and visualized study. Front Oncol. 2023;13:1077961. PMID: 36950556; PMCID: PMC10026736. https://doi.org/10.3389/fonc.2023.1077961
  32. Hu C, Zhang H, Wu W, Yu W, Li Y, Bai J, Luo B, Li S. Acupuncture for Pain Management in Cancer: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med. 2016;2016:1720239. Epub 2016 Feb 10. PMID: 26977172; PMCID: PMC4764722. https://doi.org/10.1155/2016/1720239
  33. Wang M, Yin Y, Yang H, Pei Z, Molassiotis A. Evaluating the safety, feasibility, and efficacy of non-invasive neuromodulation techniques in chemotherapy-induced peripheral neuropathy: A systematic review. Eur J Oncol Nurs. 2022;58:102124. Epub 2022 Mar 29. PMID: 35461045. https://doi.org/10.1016/j.ejon.2022.102124
  34. Anshasi HA, Ahmad M. An assessment of methodological quality of systematic reviews of acupuncture and related therapies for cancer-related pain. Complement Ther Clin Pract. 2018;32:163-168. Epub 2018 June 30. PMID: 30057045. https://doi.org/10.1016/j.ctcp.2018.06.013
  35. Xu Z, Wang X, Wu Y, Wang C, Fang X. The effectiveness and safety of acupuncture for chemotherapy-induced peripheral neuropathy: A systematic review and meta-analysis. Front Neurol. 2022;13:963358. Published online 2022 Oct 03. PMID: 36262831; PMCID: PMC9574072. https://doi.org/10.3389/fneur.2022.963358
  36. Yang J, Wahner-Roedler DL, Zhou X, Johnson LA, Do A, Pachman DR, Chon TY, Salinas M, Millstine D, Bauer BA. Acupuncture for palliative cancer pain management: systematic review. BMJ Support Palliat Care. 2021;11(3):264-270. Epub 2021 Jan 13. PMID: 33441387 PMCID: PMC8380897. https://doi.org/10.1136/bmjspcare-2020-002638
  37. De Oliveira Ruela L, Iunes DH, Nogueira DA, Stefanello J, Gradim CVC. Effectiveness of auricular acupuncture in the treatment of cancer pain: randomized clinical trial. Rev Esc Enferm USP. 2018;52:e03402. PMID: 30570087. (In Portuguese, English, Spanish). https://doi.org/10.1590/S1980-220X2017040503402
  38. Zhang Y, Sun Y, Li D, Liu X, Fang C, Yang C, Luo T, Lu H, Li H, Zhang H, Liang Q, Wu J, Huang L, Xu R, Ren L, Chen Q. Acupuncture for Breast Cancer: A Systematic Review and Meta-Analysis of Patient-Reported Outcomes. Front Oncol. 2021;11:646315. PMID: 34178633; PMCID: PMC8222976. https://doi.org/10.3389/fonc.2021.646315
  39. He Y, Guo X, May BH, Zhang AL, Liu Y, Lu C, Mao JJ, Xue CC, Zhang H. Clinical Evidence for Association of Acupuncture and Acupressure With Improved Cancer Pain: A Systematic Review and Meta-Analysis. JAMA Oncol. 2020;6(2):271-278. PMID: 31855257; PMCID: PMC6990758. https://doi.org/10.1001/jamaoncol.2019.5233
  40. Friedemann T, Kark E, Cao N, Klaßen M, Meyer-Hamme G, Greten JH, Rostock M, Buhlmann E, Zhao A, Schröder S. Acupuncture improves chemotherapy-induced neuropathy explored by neurophysiological and clinical outcomes — The randomized, controlled, cross-over ACUCIN trial. Phytomedicine. 2022;104:154294. Epub 2022 June 26. PMID: 35785559. https://doi.org/10.1016/j.phymed.2022.154294
  41. Siegel P, de Barros NF, Quispe-Cabanillas JG, Stephan C, Lima CSP. Acupuncture for cancer patients undergoing chemotherapy in a Brazilian hospital — An exploratory study. European Journal of Integrative Medicine. 2015;7(1):23-28. ISSN 1876-3820. https://doi.org/10.1016/j.eujim.2014.11.004
  42. Mai Q, Li X, Yang D, Zhang X, Peng K, Hao Y. Effects of acupressure on cancer-related pain management: A systematic review and meta-analysis of randomized controlled trials. European Journal of Integrative Medicine. 2022;51:102120. ISSN1876-3820. https://doi.org/10.1016/j.eujim.2022.102120
  43. Romeo MJ, Parton B, Russo RA, Hays LS, Conboy L. Acupuncture to Treat the Symptoms of Patients in a Palliative Care Setting. Explore (NY). 2015;11(5):357-362. Epub 2015 July 02. PMID: 26254221. https://doi.org/10.1016/j.explore.2015.06.001
  44. Ng SSM, Leung WW, Mak TWC, Hon SSF, Li JCM, Wong CYN, Tsoi KKF, Lee JFY. Electroacupuncture reduces duration of postoperative ileus after laparoscopic surgery for colorectal cancer. Gastroenterology. 2013;144(2):307-313.e1. Epub 2012 Nov 06. PMID: 23142625. https://doi.org/10.1053/j.gastro.2012.10.050
  45. Sharifi Rizi M, Shamsalinia A, Ghaffari F, Keyhanian S, Naderi Nabi B. The effect of acupressure on pain, anxiety, and the physiological indexes of patients with cancer undergoing bone marrow biopsy. Complement Ther Clin Pract. 2017;29:136-141. Epub 2017 Sept 05. PMID: 29122251. https://doi.org/10.1016/j.ctcp.2017.09.002
  46. Yang J, Wahner-Roedler DL, Zhou X, Johnson LA, Do A, Pachman DR, Chon TY, Salinas M, Millstine D, Bauer BA. Acupuncture for palliative cancer pain management: systematic review. BMJ Support Palliat Care. 2021;11(3):264-270. Epub 2021 Jan 13. PMID: 33441387; PMCID: PMC8380897. https://doi.org/10.1136/bmjspcare-2020-002638
  47. Li D-H, Su Y-F, Fan H-F, Guo N, Sun C-X. Acupuncture Combined with Three-Step Analgesic Drug Therapy for Treatment of Cancer Pain: A Systematic Review and Meta-Analysis of Randomised Clinical Trials. Evid Based Complement Alternat Med. 2021;2021:5558590. PMID: 34349826; PMCID: PMC8328698. https://doi.org/10.1155/2021/5558590
  48. Kim T-H, Kang JW, Lee TH. Therapeutic options for aromatase inhibitor-associated arthralgia in breast cancer survivors: A systematic review of systematic reviews, evidence mapping, and network meta-analysis. Maturitas. 2018;118:29-37. Epub 2018 Sept 30. PMID: 30415752. https://doi.org/10.1016/j.maturitas.2018.09.005
  49. Bae K, Lamoury G, Carroll S, Morgia M, Lim S, Baron-Hay S, Shin IS, Park SJ, Oh B. Comparison of the clinical effectiveness of treatments for aromatase inhibitor-induced arthralgia in breast cancer patients: A systematic review with network meta-analysis. Crit Rev Oncol Hematol. 2023;181:103898. Epub 2022 Dec 16. PMID: 36535489. https://doi.org/10.1016/j.critrevonc.2022.103898
  50. Greenlee H, Crew KD, Capodice J, Awad D, Buono D, Shi Z, Jeffres A, Wyse S, Whitman W, Trivedi MS, Kalinsky K, Hershman DL. Randomized sham-controlled pilot trial of weekly electro-acupuncture for the prevention of taxane-induced peripheral neuropathy in women with early stage breast cancer. Breast Cancer Res Treat. 2016;156(3):453-464. Epub 2016 Mar 25. PMID: 27013473; PMCID: PMC4924571. https://doi.org/10.1007/s10549-016-3759-2
  51. Mao JJ, Xie SX, Farrar JT, Stricker CT, Bowman MA, Bruner D, DeMichele A. A randomised trial of electro-acupuncture for arthralgia related to aromatase inhibitor use. Eur J Cancer. 2014;50(2):267-276. Epub 2013 Oct 24. PMID: 24210070; PMCID: PMC3972040. https://doi.org/10.1016/j.ejca.2013.09.022
  52. Chen L, Lin C-C, Huang T-W, Kuan Y-C, Huang Y-H, Chen H-C, Kao C-Y, Su C-M, Tam K-W. Effect of acupuncture on aromatase inhibitor-induced arthralgia in patients with breast cancer: A meta-analysis of randomized controlled trials. Breast. 2017;33:132-138. Epub 2017 Apr 04. PMID: 28384564. https://doi.org/10.1016/j.breast.2017.03.015
  53. Chien T-J, Liu C-Y, Chang Y-F, Fang C-J, Hsu C-H. Acupuncture for treating aromatase inhibitor-related arthralgia in breast cancer: A systematic review and meta-analysis. J Altern Complement Med. 2015;21(5):251-260. Epub 2015 Apr 27. PMID: 25915433; PMCID: PMC4432489. https://doi.org/10.1089/acm.2014.0083
  54. Hershman DL, Unger JM, Greenlee H, Capodice J, Lew DL, Darke A, Minasian LM, Fisch MJ, Henry NL, Crew KD. Comparison of Acupuncture vs Sham Acupuncture or Waiting List Control in the Treatment of Aromatase Inhibitor-Related Joint Pain: A Randomized Clinical Trial. JAMA Netw Open. 2022;5(11):e2241720. PMID: 36367721; PMCID: PMC9652759. https://doi.org/10.1001/jamanetworkopen.2022.41720
  55. Qi Q-L, Han X, Tang C. Effects of Acupuncture on Breast Cancer Patients Taking Aromatase Inhibitors. Biomed Res Int. 2022;2022:1164355. PMID: 36132087; PMCID: PMC9484888. https://doi.org/10.1155/2022/1164355
  56. Kashyap K, Bhatnagar S. Evidence for the Efficacy of Scrambler Therapy for Cancer Pain: A Systematic Review. Pain Physician. 2020;23(4):349-364. PMID: 32709170.
  57. Kashyap K, Singh V, Mishra S, Dwivedi SN, Bhatnagar S. The Efficacy of Scrambler Therapy for the Management of Head, Neck and Thoracic Cancer Pain: A Randomized Controlled Trial. Pain Physician. 2020;23(5):495-506. PMID: 32967392.
  58. Coyne PJ, Wan W, Dodson P, Swainey C, Smith TJ. A trial of Scrambler therapy in the treatment of cancer pain syndromes and chronic chemotherapy-induced peripheral neuropathy. J Pain Palliat Care Pharmacother. 2013;27(4):359-364. Epub 2013 Oct 21. PMID: 24143893; PMCID: PMC4378693. https://doi.org/10.3109/15360288.2013.847519
  59. Huang W, Long W, Xiao J, Zhao G, Yu T. Effect of electrically stimulating acupoint, Zusanli (ST 36), on patient’s recovery after laparoscopic colorectal cancer resection: A randomized controlled trial. J Tradit Chin Med. 2019;39(3):433-439. PMID: 32186016.
  60. Wong R, Major P, Sagar S. Phase 2 Study of Acupuncture-Like Transcutaneous Nerve Stimulation for Chemotherapy-Induced Peripheral Neuropathy. Integr Cancer Ther. 2016;15(2):153-164. Epub 2016 Apr 29. PMID: 27130723; PMCID: PMC5736058. https://doi.org/10.1177/1534735415627926
  61. Gewandter JS, Chaudari J, Ibegbu C, Kitt R, Serventi J, Burke J, Culakova E, Kolb N, Sluka KA, Tejani MA, Mohile NA. Wireless transcutaneous electrical nerve stimulation device for chemotherapy-induced peripheral neuropathy: an open-label feasibility study. Support Care Cancer. 2019;27(5):1765-1774. Epub 2018 Aug 27. PMID: 30151681; PMCID: PMC6393221. https://doi.org/10.1007/s00520-018-4424-6
  62. He L, Tan K, Lin X, Yi H, Wang X, Zhang J, Lin J, Lin L. Multicenter, randomized, double-blind, controlled trial of transcutaneous electrical nerve stimulation for pancreatic cancer related pain. Medicine (Baltimore). 2021;100(5):e23748. PMID: 33592831; PMCID: PMC7870216. https://doi.org/10.1097/MD.0000000000023748
  63. Siemens W, Boehlke C, Bennett MI, Offner K, Becker G, Gaertner J. Transcutaneous electrical nerve stimulation for advanced cancer pain inpatients in specialist palliative care-a blinded, randomized, sham-controlled pilot cross-over trial. Support Care Cancer. 2020;28(11):5323-5333. Epub 2020 Mar 03. PMID: 32128614; PMCID: PMC7547037. https://doi.org/10.1007/s00520-020-05370-8
  64. Püsküllüoğlu M, Tomaszewski KA, Grela-Wojewoda A, Pacholczak-Madej R, Ebner F. Effects of Transcutaneous Electrical Nerve Stimulation on Pain and Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients: A Systematic Review. Medicina (Kaunas). 2022;58(2):284. PMID: 35208610; PMCID: PMC8876365. https://doi.org/10.3390/medicina58020284

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