The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2026
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Baranich A.I.

Burdenko Neurosurgical Center, Moscow, Russia;
Plekhanov Russian University of Economics, Moscow, Russia

Sychev A.A.

Burdenko Neurosurgical Center, Moscow, Russia

Savin I.A.

Burdenko Neurosurgical Center, Moscow, Russia

Kurdyumova N.V.

Burdenko Neurosurgical Center, Moscow, Russia

Sukhorukova M.V.

Burdenko Neurosurgical Center, Moscow, Russia

Veliev Z.Sh.

Burdenko Neurosurgical Center, Moscow, Russia

Korotkov D.S.

Burdenko Neurosurgical Center, Moscow, Russia

Kakurin K.O.

Pirogov Russian National Research Medical University, Moscow, Russia

Kudrina V.G.

Plekhanov Russian University of Economics, Moscow, Russia;
Russian Medical Academy of Continuous Professional Education, Moscow, Russia

Causes and microbiological spectrum of brain abscesses: modern data

Authors:

Baranich A.I., Sychev A.A., Savin I.A., Kurdyumova N.V., Sukhorukova M.V., Veliev Z.Sh., Korotkov D.S., Kakurin K.O., Kudrina V.G.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2026;90(3): 37‑42

DOI: 10.17116/neiro20269003137

Read: 304 times

Contact the author
Table of contents

CAUSES AND MICROBIOLOGICAL SPECTRUM OF BRAIN ABSCESSES: MODERN DATA
CAUSES AND MICROBIOLOGICAL SPECTRUM OF BRAIN ABSCESSES: MODERN DATA

To cite this article:

Baranich AI, Sychev AA, Savin IA, et al. Causes and microbiological spectrum of brain abscesses: modern data. Burdenko's Journal of Neurosurgery. 2026;90(3):37‑42. (In Russ.)
https://doi.org/10.17116/neiro20269003137

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
Recommended articles:
Comparison of various psoriasis treatment methods. Russian Journal of Clinical Dermatology and Vene­reology. 2026;(3):436-442
Abstract:

Brain abscesses are relatively rare, yet they are life-threatening infections with high risk of persistent neurological impairment in survivors. Effectiveness of therapy depends on understanding the range of probable pathogens. This enables optimal empirical therapy avoiding broad-spectrum combinations and associated risks of drug-drug interactions. Available Russian literature predominantly contains case reports and reviews resulting in a lack of up-to-date epidemiological data on brain abscesses.

OBJECTIVE

To analyze current etiological and epidemiological data in a cohort of patients with verified brain abscesses.

MATERIAL AND METHODS

A single-center retrospective study enrolled 41 patients with primary brain abscesses between 2022 and 2025. The diagnosis was confirmed by contrast-enhanced MRI and/or intraoperative findings. Exclusion criteria: extracranial abscess, concomitant intracranial or head soft tissue infection and recurrent abscesses.

RESULTS

Abscesses occurred as complications of neurosurgery in 16 (39%) out of 41 patients, ENT diseases — in 4 (9.8%) cases. Odontogenic route of infection was established in 4 (9.8%) cases, and 2 (4.9%) patients had previous traumatic brain injury. Etiology was unknown in 36.6% of cases. Gram-positive cocci prevailed: Staphylococcus spp. (26.8%) and Streptococcus spp. (19.5%).

CONCLUSION

These data highlight the need for regular updating of local epidemiological data on brain abscesses. A thorough analysis of anamnestic data in these patients can enable informed and timely prescription of appropriate empirical antimicrobial therapy. Choice of this therapy depends crucially on spectrum of probable pathogens, especially in the absence of microbiological verification.

Keywords:

brain abscesses
CNS infections
Staphylococcus spp
infectious complications

Authors:

Baranich A.I.

Burdenko Neurosurgical Center, Moscow, Russia;
Plekhanov Russian University of Economics, Moscow, Russia

Sychev A.A.

Burdenko Neurosurgical Center, Moscow, Russia

Savin I.A.

Burdenko Neurosurgical Center, Moscow, Russia

Kurdyumova N.V.

Burdenko Neurosurgical Center, Moscow, Russia

Sukhorukova M.V.

Burdenko Neurosurgical Center, Moscow, Russia

Veliev Z.Sh.

Burdenko Neurosurgical Center, Moscow, Russia

Korotkov D.S.

Burdenko Neurosurgical Center, Moscow, Russia

Kakurin K.O.

Pirogov Russian National Research Medical University, Moscow, Russia

Kudrina V.G.

Plekhanov Russian University of Economics, Moscow, Russia;
Russian Medical Academy of Continuous Professional Education, Moscow, Russia

Received:

04.02.2025

Accepted:

12.03.2026

Close metadata

References:

  1. Bodilsen J, D’Alessandris QG, Humphreys H, Iro MA, Klein M, Last K, Montesinos IL, Pagliano P, Sipahi OR, San-Juan R, Tattevin P, Thurnher M, de J Treviño-Rangel R, Brouwer MC; ESCMID Study Group for Infections of the Brain (ESGIB). European society of Clinical Microbiology and Infectious Diseases guidelines on diagnosis and treatment of brain abscess in children and adults. Clinical Microbiology and Infection. 2024;30(1):66-89.  https://doi.org/10.1016/j.cmi.2023.08.016
  2. Bodilsen J, Eriksen EM, Nielsen MD, Duerlund LS, Mariager T, Nielsen H, Brouwer MC. Clinical features and outcome of brain abscess after introduction of CT and MRI: A meta-analysis. Journal of Infection. 2025;90(2):106394. https://doi.org/10.1016/j.jinf.2024.106394
  3. Bilgin E, Arslan Gulen T, Kızılpınar G, Işıkber GG, Sezer C, Tas ZA, Oruc E. The characteristics of the cases with brain abscess and the analysis of the predictive factors for poor outcome. The Journal of Infection in Developing Countries. 2025;19(8):1182-1188. https://doi.org/10.3855/jidc.20676
  4. Baranich AI, Sychev AA, Savin IA, Kudrina VG. Drug interactions in neurosurgical patients. Burdenko’s Journal of Neurosurgery. 2023;87(6):100-105. (In Russ.). https://doi.org/10.17116/neiro202387061100
  5. Dzhindzhikhadze RS, Dreval ON, Lazarev VA, Polyakov AV, Kambiev RL, Fedorov DN, Banina VB, Barbashova AS. Successful microsurgical resection of a large brainstem abscess: case report and literature review. Burdenko’s Journal of Neurosurgery. 2022;86(3):56-62. (In Russ.). https://doi.org/10.17116/neiro20228603156
  6. Ortenberg EA, Veshkurtzeva IM. Intracranial abscesses: some clinical pharmacology issues of a multidisciplinary approach. Clinical Microbiology and Antimicrobial Chemotherapy. 2025;27(1):27-32. (In Russ.). https://doi.org/10.36488/cmac.2025.1.27-32
  7. Brouwer MC, Coutinho JM, van de Beek D. Clinical characteristics and outcome of brain abscess: systematic review and meta-analysis. Neurology. 2014;82(9):806-813.  https://doi.org/10.1212/WNL.0000000000000172
  8. Cai Y, Liu J, Jia G, Hou Y, Wang Y. Clinical characteristics, complications, and outcome of brain abscess treated by stereotactic aspiration: a retrospective analysis. BMC Infectious Diseases. 2025;25(1):373.  https://doi.org/10.1186/s12879-025-10770-4
  9. Lange N, Berndt M, Jörger AK, Wagner A, Lummel N, Ryang YM, Wantia N, Meyer B, Gempt J. Clinical Characteristics and Course of Postoperative Brain Abscess. World Neurosurgery. 2018;120:e675-e683. https://doi.org/10.1016/j.wneu.2018.08.143
  10. Anwar S, Acharya S, Thapa K, Adhikari N, Mobarakai N. Brain Abscesses by Nocardia: An Interesting Case. Cureus. 2023;15(5):e38911. https://doi.org/10.7759/cureus.38911
  11. Vega Brizneda M, Miranda C, Cober E, Misra A, Harrington S, Yetmar ZA. Risk Factors and Outcomes of Disseminated Nocardiosis Across Host Risk Groups. Open Forum Infectious Diseases. 2026;13(1):ofag008. https://10.1093/ofid/ofag008
  12. Qin L, Wang S, Zheng Z, Zhang W, Qu Q, Li J, Tan Y, Cao L. A complicated infection by cutaneous Nocardia wallacei and pulmonary Mycobacterium abscessus in a Chinese immunocompetent patient: a case report. Frontiers in Cellular and Infection Microbiology. 2023;13:1229298. https://doi.org/10.3389/fcimb.2023.1229298
  13. Ziogou A, Giannakodimos A, Giannakodimos I, Baliou S, Tsantes AG, Ioannou P. Nocardia Osteomyelitis in Humans-A Narrative Review of Reported Cases, Microbiology, and Management. Pathogens. 2025;14(10):1032. https://doi.org/10.3390/pathogens14101032
  14. Bristowe H, Dissanayake K, Chandra J, Arias M. Listeria brain abscess: a therapeutically challenging rare presentation of listeriosis. BMC Infectious Diseases. 2024;24(1):477.  https://doi.org/10.1186/s12879-024-09295-z
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.