The FOUR scale in assessing patients with acute cerebral insufficiency
Журнал: Вопросы нейрохирургии имени Н.Н. Бурденко. 2026;90(1):57-64.
DOI: 10.17116/neiro20269001157
Read: 1778 раз
Abstract
Treatment and rehabilitation of patients with acute cerebral insufficiency necessitate critical objectives (assessment of brain damage severity and prediction of potential outcomes). Despite the role of this stage, current consciousness assessment methods often lack sufficient accuracy and objectivity. A promising approach is the Full Outline of UnResponsiveness scale (FOUR) providing objective patient evaluation compared to traditional Glasgow Coma scale.
OBJECTIVE
To evaluate clinical significance of the FOUR scale for patients with cerebral insufficiency.
MATERIAL AND METHODS
A prospective single-center study included 200 patients with acute cerebral insufficiency. Analysis employed ROC curves, logistic regression and correlation methods.
RESULTS
The FOUR scale demonstrated high prognostic accuracy in comatose patients (AUC=0.944 vs. 0.742 for GCS, p< 0.001). Strong correlations were found between FOUR scores and GOS grades (rs=0.7546, p<0.0001), as well as prediction of mortality (OR=3.4, 95% CI 2.1—5.6). For patients with chronic consciousness disorders, the FOUR scale showed benefits (AUC=0.936 vs. 0.745 for GCS).
CONCLUSION
The FOUR scale represents an optimal monitoring tool for patients with cerebral insufficiency.
Keywords
- coma
- chronic disorders of consciousness
- FOUR
- GCS
- acute cerebral insufficiency
Дата поступления: 04.08.2025
Дата принятия в печать: 26.11.2026
Дата публикации: 11.02.2026
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