Clinical and neuropsychological survey of patients with glioma of the corpus callosum

Buklina S.B.; Pitskhelauri D.I.; Beshplav Sh.T.

doi:https://doi.org/10.17116/neiro20228602180

Buklina S.B.

Burdenko Neurosurgical Center

Pitskhelauri D.I.

Skolkovo Institute of Science and Technology

SPIN RSCI: 3261-2144
Scopus AuthorID: 6507820245
ORCID: 0000-0003-0374-7970

Beshplav Sh.T.

Burdenko Neurosurgical Center

Clinical and neuropsychological survey of patients with glioma of the corpus callosum

Authors:

Buklina S.B., Pitskhelauri D.I., Beshplav Sh.T.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2022;86(2): 80‑88

DOI: 10.17116/neiro20228602180

Read: 6497 times

To cite this article:

Buklina SB, Pitskhelauri DI, Beshplav ShT. Clinical and neuropsychological survey of patients with glioma of the corpus callosum. Burdenko's Journal of Neurosurgery. 2022;86(2):80‑88. (In Russ., In Engl.)
https://doi.org/10.17116/neiro20228602180

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)

Использование инфографики авторами научных работ

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Abstract:

BACKGROUND

We found no reports devoted to a comprehensive analysis of cognitive impairment that can determine the quality of life in patients with glioma of the corpus callosum and topical affiliation of these disorders.

OBJECTIVE

Clinical and neuropsychological study of mental disorders in patients with gliomas of the corpus callosum, qualification of topical affiliation of the identified syndromes.

MATERIAL AND METHODS

We examined 30 patients with gliomas of the corpus callosum using the Luria’s approach to clinical and neuropsychological survey.

RESULTS

We identified the features of cognitive impairment depending on localization of glioma in the corpus callosum. Non-spontaneity, reduced criticism to own condition up to denial of disease and memory impairment were more common in patients with anterior gliomas of the corpus callosum. These disorders can be associated with tumor spread into medial parts of frontal lobes. Subcortical symptoms including hypomimia, quiet dull voice, involuntary urination, severe disorders of dynamic praxis and memory impairment were more common in patients with glioma of the middle part of the corpus callosum. These disorders can be associated with dorsal tumor spread towards posterior part of the frontal lobe or ventrally towards the basal ganglia. Memory disorders more often manifested by Korsakoff syndrome prevailed in patients with posterior gliomas of the corpus callosum. This finding can be associated with ventral growth of tumor towards the fornix.

CONCLUSION

We identified the features of cognitive impairment depending on localization of glioma in the corpus callosum. Split-brain symptoms were rare in these patients and observed in lesions of middle and posterior parts of the corpus callosum only in 3 patients.

Keywords:

glioma of the corpus callosum

butterfly glioblastoma

glioma-associated cognitive impairment

Authors:

Buklina S.B.

Burdenko Neurosurgical Center

Pitskhelauri D.I.

Skolkovo Institute of Science and Technology

SPIN RSCI: 3261-2144
Scopus AuthorID: 6507820245
ORCID: 0000-0003-0374-7970

Beshplav Sh.T.

Burdenko Neurosurgical Center

Received:

30.04.2021

Accepted:

28.01.2022

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References:

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