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Buklina S.B.

Burdenko Neurosurgical Center

Zhukov V.Yu.

Burdenko Neurosurgical Center

Goryainov S.A.

Burdenko Neurosurgical Center

Batalov A.I.

Burdenko Neurosurgical Center

Afandiev R.M.

Burdenko Neurosurgical Center

Maryashev S.A.

Burdenko National Medical Scientific Center for Neurosurgery

Vologdina Ya.O.

Burdenko Neurosurgical Center

Bykanov A.E.

Burdenko Neurosurgical Center

Conduction aphasia in patients with glioma in the left hemisphere

Authors:

Buklina S.B., Zhukov V.Yu., Goryainov S.A., Batalov A.I., Afandiev R.M., Maryashev S.A., Vologdina Ya.O., Bykanov A.E.

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Journal: Burdenko's Journal of Neurosurgery. 2021;85(4): 29‑40

DOI: 10.17116/neiro20218504129

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Table of contents

CONDUCTION APHASIA IN PATIENTS WITH GLIOMA IN THE LEFT HEMISPHERE
CONDUCTION APHASIA IN PATIENTS WITH GLIOMA IN THE LEFT HEMISPHERE

To cite this article:

Buklina SB, Zhukov VYu, Goryainov SA, et al. . Conduction aphasia in patients with glioma in the left hemisphere. Burdenko's Journal of Neurosurgery. 2021;85(4):29‑40. (In Russ., In Engl.)
https://doi.org/10.17116/neiro20218504129

Подписка 2025-2 (Burdenko's Journal of Neurosurgery)
 
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Background. According to Wernicke-Geschwind model, conduction aphasia following arcuate tract lesion was canonized as primary disorder of repetition in relatively intact speech.

OBJECTIVE

Syndromic analysis of speech and writing disorders in patients with arcuate tract lesion using the method by A.R. Luria and their comparison with well-known types of aphasia.

MATERIAL AND METHODS

Clinical and neuropsychological survey was performed in 14 patients with gliomas who underwent surgical treatment at the Burdenko Neurosurgical Center (10 gliomas of the frontal lobe and 4 tumors of the temporal lobe). All patients underwent MRI, HARDI MRI tractography and A.R. Luria’s neuropsychological examination prior to surgery and after 5—6 postoperative days. Thirteen patients underwent awake craniotomy, 3 of them were examined one year after surgery.

RESULTS

In all patients, the tumor was localized near arcuate tract and its infiltration was noted. No intraoperative damage to the tract was ever noted according to speech monitoring data. However, postoperative edema followed by infiltration and dislocation of the tract (in all patients), as well as local ischemia in 4 patients were observed. After resection of prefrontal and premotor gliomas, aphasia included frontal (perseveration) and temporal components (disorders of naming, auditory-speech memory). Unusual verbal paraphrases were noted. We also observed severe violation of writing (temporal type) even if spontaneous speech and repetition were preserved. In case of resection of deep posterior temporal gliomas, speech disorders included signs of frontal lobe lesion (perseveration) and writing disorders. Similar motor abnormalities were identified in writing.

CONCLUSION

Arcuate tract lesion can result speech and writing disorders as signs of damage to certain cortical speech zones (frontal and temporal lobe). Violations of repetition were not predominant in any case. At the same time, interruption of connection between motor and auditory image of the word could be revealed in writing.

Keywords:

conduction aphasia
arcuate tract
disorders of writing

Authors:

Buklina S.B.

Burdenko Neurosurgical Center

Zhukov V.Yu.

Burdenko Neurosurgical Center

Goryainov S.A.

Burdenko Neurosurgical Center

Batalov A.I.

Burdenko Neurosurgical Center

Afandiev R.M.

Burdenko Neurosurgical Center

Maryashev S.A.

Burdenko National Medical Scientific Center for Neurosurgery

Vologdina Ya.O.

Burdenko Neurosurgical Center

Bykanov A.E.

Burdenko Neurosurgical Center

Received:

27.06.2020

Accepted:

19.03.2021

List of references:

  1. Benson DF, Sheremata WA, Bouchard R, Segarra JM, Price D, Geschwind N. Conduction aphasia. A clinicopathological stady. Archives of Neurology. 1973;28(5):339-346.  https://doi.org/10.1001/archneur.1973.00490230075011
  2. Catani M, Ffytche DH. The rise and falls of disconnection syndromes. Brain. 2005;128(Pt 10):2224-2239. https://doi.org/10.1093/brain/awh622
  3. Catani M, Jones DK, Ffytche DH. Perisylvian language networks of the human brain. Annals of Neurology. 2005;57(1):8-16.  https://doi.org/10.1002/ana.20319
  4. Bernal B, Ardila A. The role of the arcuate fasciculus in conduction aphasia. Brain. 2009;132(Pt 9):2309-2316. https://doi.org/10.1093/brain/awp206
  5. Ardila A. A review of conduction aphasia. Current Neurology and Neuroscience Reports. 2010;10(6):499-503.  https://doi.org/10.1007/s11910-010-0142-2
  6. Acharya AB, Maani CV. Conduction Aphasia. Source StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019.
  7. Bartha L, Benke T. Acute conduction aphasia: an analysis of 20 cases. Brain and Language. 2003;85(1):93-108.  https://doi.org/10.1016/s0093-934x(02)00502-3
  8. Baldo JV, Klostermann EC, Dronkers NF. It’s either a cook or a baker: patients with conduction aphasia get the gist but lose the trace. Brain and Language. 2008;105(2):134-140.  https://doi.org/10.1016/j.bandl.2007.12.007
  9. Buchsbaum BR, Baldo J, Okada K, Berman KF, Dronkers N, D’Esposito M, Hickok G. Conduction aphasia, sensory-motor integration, and phonological short-term memory — an aggregate analysis of lesion and fMRI data. Brain and Language. 2011;119(3):119-128.  https://doi.org/10.1016/j.bandl.2010.12.001
  10. Bizzi A, Nava S, Ferrè F, Castelli G, Aquino D, Ciaraffa F, Broggi G, DiMeco F, Piacentini S. Aphasia induced by gliomas growing in the ventrolateral frontal region: assessment with diffusion MR tractography, functional MR imaging and neuropsychology. Cortex. 2012;48(2):255-272.  https://doi.org/10.1016/j.cortex.2011.11.015
  11. Sidiropoulos K, Ackermann H, Wannke M, Hertrich I. Temporal processing capabilities in repetition conduction aphasia. Brain and Cognition. 2010;73(3):194-202.  https://doi.org/10.1016/j.bandc.2010.05.003
  12. Sidiropoulos K, de Bleser R, Ablinger I, Ackermann H. The relationship between verbal and nonverbal auditory signal processing in conduction aphasia: behavioral and anatomical evidence for common decoding mechanisms. Neurocase. 2015;21(3):377-393.  https://doi.org/10.1080/13554794.2014.902471
  13. Luriya AR. Travmaticheskie afazii. M.: Izd-vo AMN SSSR; 1947. (In Russ.).
  14. Luriya AR. Osnovnye problemy nejrolingvistiki. M.: Izd-vo «Librokom»; 2009. (In Russ.).
  15. Geschwind N. Disconnexion syndromes in animals and man. Brain. 1965;88(2):237-294.  https://doi.org/10.1093/brain/88.2.237
  16. Catani M, Mesulam M. The arcuate fasciculus and the disconnection theme in language and aphasia: history and current state. Cortex. 2008;44(8):953-961.  https://doi.org/10.1016/j.cortex.2008.04.002
  17. Bykanov AE, Pitskhelauri DI, Batalov AI, Pronin IN, Shkarubo MA, Dobrovol’sky GF, Kobyakov GL, Buklina SB, Puchkov VL, Zakharova NE, Smirnov AS, Sanikidze AZ, Gol’bin DA, Pogosbekyan EL, Kudieva ES, Shkatova AM, Potapov AA. Surgical anatomy of the peri-insular associative tracts. Part I. System of the upper longitudinal beam. Voprosy nejrohirurgii imeni N.N. Burdenko. 2017;81(1):26-38. (In Russ.). https://doi.org/10.17116/neiro201780726-38
  18. Geldmacher DS, Quigg M, Elias WJ. MR tractography depicting damage to the arcuate fasciculus in a patient with conduction aphasia. Neurology. 2007;69(3):321-322.  https://doi.org/10.1212/01.wnl.0000275278.38229.7b
  19. Zhang Y, Wang C, Zhao X, Chen H, Han Z, Wang Y. Diffusion tensor imaging depicting damage to the arcuate fasciculus in patients with conduction aphasia: a study of the Wernicke-Geschwind model. Neurological Research. 2010;32(7):775-778.  https://doi.org/10.1179/016164109X12478302362653
  20. Marchina S, Zhu LL, Norton A, Zipse L, Wan CY, Schlaug G. Impairment of speech production predicted by lesion load of the left arcuate fasciculus. Stroke. 2011;42(8):2251-2256. https://doi.org/10.1161/STROKEAHA.110.606103
  21. Song X, Dornbos D 3rd, Lai Z, Zhang Y, Li T, Chen H, Yang Z. Diffusion tensor imaging and diffusion tensor imaging-fibre tractograph depict the mechanisms of Broca-like and Wernicke-like conduction aphasia. Neurological Research. 2011;33(5):529-535.  https://doi.org/10.1179/016164111X13007856084322
  22. Berthier ML, Lambon Ralph MA, Pujol J, Green C. Arcuate fasciculus variability and repetition: the left sometimes can be right. Cortex. 2012;48(2):133-143.  https://doi.org/10.1016/j.cortex.2011.06.014
  23. López-Barroso D, Catani M, Ripollés P, Dell’Acqua F, Rodríguez-Fornells A, de Diego-Balaguer R. Word learning is mediated by the left arcuate fasciculus. Proceedings of the National Academy of Sciences of the United States of America. 2013;110(32):13168-13173. https://doi.org/10.1073/pnas.1301696110
  24. Tak HJ, Jang SH. Relation between aphasia and arcuate fasciculus in chronic stroke patients. BMC Neurology. 2014;14:46.  https://doi.org/10.1186/1471-2377-14-46
  25. Jang SH, Cho IT, Lim JW. Recovery of aphasia and change of injured arcuate fasciculus in the dominant hemisphere in stroke patients. NeuroRehabilitation. 2017;41(4):759-764.  https://doi.org/10.3233/NRE-172167
  26. Kempler D, Metter EJ, Jackson CA, Hanson WR, Riege WH, Mazziotta JC, Phelps ME. Disconnection and cerebral metabolism. The case of conduction aphasia. Archives of Neurology. 1988;45(3):275-279.  https://doi.org/10.1001/archneur.1988.00520270049020
  27. Ibayashi K. A case of conduction aphasia due to small infarction in the left parietal lobe. Clinical Neurology. 2002;42(8):731-735. 
  28. Quigg M, Geldmacher DS, Elias WJ. Conduction aphasia as a function of the dominant posterior perisylvian cortex. Report of two cases. Journal of Neurosurgery. 2006;104(5):845-848.  https://doi.org/10.3171/jns.2006.104.5.845
  29. Tomasino B, Marin D, Maieron M, D’Agostini S, Medeossi I, Fabbro F, Skrap M, Luzzatti C. A multimodal mapping study of conduction aphasia with impaired repetition and spared reading aloud. Neuropsychologia. 2015;70:214-226.  https://doi.org/10.1016/j.neuropsychologia.2015.02.023
  30. Binder JR. Current Controversies on Wernicke’s Area and its Role in Language. Current Neurology and Neuroscience Reports. 2017;17(8):58.  https://doi.org/10.1007/s11910-017-0764-8
  31. Anderson JM, Gilmore R, Roper S, Crosson B, Bauer RM, Nadeau S, Beversdorf DQ, Cibula J, Rogish M 3rd, Kortencamp S, Hughes JD, Gonzalez Rothi LJ, Heilman KM. Conduction aphasia and the arcuate fasciculus: A reexamination of the Wernicke-Geschwind model. Brain and Language. 1999;70(1):1-12.  https://doi.org/10.1006/brln.1999.2135
  32. Zöllner JP, Haag A, Hermsen A, Bauer S, Stahl F, Wulf K, Menzler K, Reif PS, Wagner M, Pagenstecher A, Sure U, Knake S, Rosenow F, Strzelczyk A. Ictal conduction aphasia and ictal angular gyrus syndrome as rare manifestations of epilepsy: The importance of ictal testing during video-EEG monitoring. Epilepsy and Behavior Case Reports. 2017;8:55-62.  https://doi.org/10.1016/j.ebcr.2017.07.003
  33. Luriya AR. Narusheniya vysshih korkovyh funkcij pri ochagovyh porazheniyah golovnogo mozga. M.: Izd-vo MGU; 1962. (In Russ.).
  34. Bizyuk AP. Kompendium metodov nejropsihologicheskogo obsledovaniya. SPb.: Rech’; 2005. (In Russ.).
  35. Dragoj OV, Krabis AV, Tolkacheva VA, Buklina SB. Russian Intraoperative Naming Test: a standardized tool for mapping the function of naming nouns and verbs during neurosurgical operations in consciousness. Rossijskij zhurnal kognitivnoj nauki. 2016;3(4):4-25. (In Russ.).
  36. Luriya AR. Ocherki psihofiziologii pis’ma. M.: Izd-vo APN RSFSR; 1950. (In Russ.).
  37. Fridriksson J, Guo D, Fillmore P, Holland A, Rorden C. Damage to the anterior arcuate fasciculus predicts non-fluent speech production in aphasia. Brain. 2013;136(Pt 11):3451-3460. https://doi.org/10.1093/brain/awt267
  38. Buklina SB. Narusheniya vysshih psihicheskih funkcij pri porazhenii glubinnyh i stvolovyh struktur golovnogo mozga. M.: Izd-vo «Medpress»; 2018. (In Russ.).
  39. Li EC, Williams SE. Repetition deficits in three aphasic syndromes. Journal of Communication Disorders. 1990;23(1):77-88.  https://doi.org/10.1016/0021-9924(90)90014-p
  40. Tkach JA, Chen X, Freebairn LA, Schmithorst VJ, Holland SK, Lewis BA. Neural correlates of phonological processing in speech sound disorder: a functional magnetic resonance imaging study. Brain and Language. 2011;119(1):42-49.  https://doi.org/10.1016/j.bandl.2011.02.002

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