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Khachatryan R.G.

Almazov National Medical Research Center

Bart V.A.

Almazov National Medical Research Center;
Saint-Petersburg State University

Maslova L.N.

Almazov National Medical Research Center

Fadeeva T.N.

Almazov National Medical Research Center

Sebelev K.I.

Almazov National Medical Research Center

Tastanbekov M.M.

Almazov National Medical Research Center

Alekseeva T.M.

I.M. Sechenov First Moscow State Medical University

Khachatryan V.A.

Almazov National Medical Research Center

Clinical, structural and functional features of paroxismal syndrome in insular and temporal lobe tumors

Authors:

Khachatryan R.G., Bart V.A., Maslova L.N., Fadeeva T.N., Sebelev K.I., Tastanbekov M.M., Alekseeva T.M., Khachatryan V.A.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2020;84(4): 36‑45

DOI: 10.17116/neiro20208404136

Views: 3532

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Table of contents

CLINICAL, STRUCTURAL AND FUNCTIONAL FEATURES OF PAROXISMAL SYNDROME IN INSULAR AND TEMPORAL LOBE TUMORS
CLINICAL, STRUCTURAL AND FUNCTIONAL FEATURES OF PAROXISMAL SYNDROME IN INSULAR AND TEMPORAL LOBE TUMORS

To cite this article:

Khachatryan RG, Bart VA, Maslova LN, et al. . Clinical, structural and functional features of paroxismal syndrome in insular and temporal lobe tumors. Burdenko's Journal of Neurosurgery. 2020;84(4):36‑45. (In Russ., In Engl.)
https://doi.org/10.17116/neiro20208404136

Подписка 2025-2 (Burdenko's Journal of Neurosurgery)
 
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OBJECTIVE

To analyze the characteristics of paroxysmal syndrome in insular and temporal lobe tumors, to determine their relationship with the histological structure of tumor, to assess the effect of tumor growth nature on severity of disease.

MATERIAL AND METHODS

A retrospective analysis enrolled 80 patients aged 11 — 80 years with insular and temporal lobe tumors and symptomatic epilepsy. All patients underwent surgery at the Polenov National Research Neurosurgery Center in Almazov National Medical Research Center for the period from 2012 to 2018.

RESULTS

The main group consisted of 29 patients with tumors of temporal and insular lobes. Control group of 51 patients with temporal gliomas was formed for comparative analysis. It was found that involvement of insular lobe into paroxysmal syndrome is characterized by attacks with a motor component, somatosensory paroxysms, vegetative manifestations (respiratory attacks, salivation, nausea), speech disorders and taste hallucinations. Derealization, motor arrest and déjà vu/jamis vu paroxysms were more common in patients with temporal lobe lesion. Neoplastic lesion of the insular lobe shortens the period between manifestation of paroxysms and surgical treatment. Moreover, this type of disease is characterized by higher incidence of seizures compared to isolated temporal lobe tumors.

Keywords:

insular epilepsy
temporal lobe epilepsy
insular glioma
epilepsy surgery

Authors:

Khachatryan R.G.

Almazov National Medical Research Center

Bart V.A.

Almazov National Medical Research Center;
Saint-Petersburg State University

Maslova L.N.

Almazov National Medical Research Center

Fadeeva T.N.

Almazov National Medical Research Center

Sebelev K.I.

Almazov National Medical Research Center

Tastanbekov M.M.

Almazov National Medical Research Center

Alekseeva T.M.

I.M. Sechenov First Moscow State Medical University

Khachatryan V.A.

Almazov National Medical Research Center

Received:

16.01.2020

Accepted:

24.04.2020

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