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Chritinin D.F.

Sechenov First Moscow State Medical University (Sechenov University)

Shamrey V.K.

Kirov Military Medical Academy

Kurasov E.S.

Kirov Military Medical Academy

Litvinenko I.V.

Kirov Military Medical Academy

Tsygan N.V.

Kirov Military Medical Academy;
Konstantinov Peterburg Institute of Nuclear Physics of the National Research Center «Kurchatov Institute»

Golokhvastov S.Yu.

Kirov Military Medical Academy

Ryabtsev A.V.

Kirov Military Medical Academy;
Konstantinov Petersburg Institute of Nuclear Physics of the National Research Center «Kurchatov Institute»;
National Research Center «Kurchatov Institute»

Some psychiatric and neurological aspects of the asymptomatic and mild course of COVID-19

Authors:

Chritinin D.F., Shamrey V.K., Kurasov E.S., Litvinenko I.V., Tsygan N.V., Golokhvastov S.Yu., Ryabtsev A.V.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(12): 13‑18

DOI: 10.17116/jnevro202112112113

Read: 1841 times

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Table of contents

SOME PSYCHIATRIC AND NEUROLOGICAL ASPECTS OF THE ASYMPTOMATIC AND MILD COURSE OF COVID-19
SOME PSYCHIATRIC AND NEUROLOGICAL ASPECTS OF THE ASYMPTOMATIC AND MILD COURSE OF COVID-19

To cite this article:

Chritinin DF, Shamrey VK, Kurasov ES, Litvinenko IV, Tsygan NV, Golokhvastov SYu, Ryabtsev AV. Some psychiatric and neurological aspects of the asymptomatic and mild course of COVID-19. S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(12):13‑18. (In Russ.)
https://doi.org/10.17116/jnevro202112112113

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
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Abstract:

OBJECTIVE

To study neurological and mental disorders associated with the inapparent and mild course of COVID-19.

MATERIAL AND METHODS

The study included 50 patients (mean age 35.2±11.4 years) admitted to a psychiatric hospital due to depressive spectrum disorders. Patients were divided into two groups: patients (n=16) who had IgG antibodies to SARS-CoV-2 (main group) and patients (n=34) without a history of COVID-19 (comparison group).

RESULTS AND CONCLUSION

Patients of the main group showed a difference in the structure of asthenic disorders compared with the comparison group. Also, there was a significant predominance of the severity of asthenic symptoms and anxiety in the structure of psychopathological disorders in depressive spectrum disorders. The viral intoxication contributes to the formation of a kind of asthenic «soil» (with characteristic manifestations). In the future, in the case of the development of any stress-associated disorder, more pronounced psychopathological disorders are noted compared with patients of the comparison group. The authors describe a variant of the course of COVID-19, in which the development of ischemic stroke was the first clinical manifestation of the disease. These disorders are based on the pronounced neurotropic effect of SARS-CoV-2 and its effect on the neurovascular unit.

Keywords:

neurological disorders
psychopathological symptoms
COVID-19
mild course
neurotropic effect

Authors:

Chritinin D.F.

Sechenov First Moscow State Medical University (Sechenov University)

Shamrey V.K.

Kirov Military Medical Academy

Kurasov E.S.

Kirov Military Medical Academy

Litvinenko I.V.

Kirov Military Medical Academy

Tsygan N.V.

Kirov Military Medical Academy;
Konstantinov Peterburg Institute of Nuclear Physics of the National Research Center «Kurchatov Institute»

Golokhvastov S.Yu.

Kirov Military Medical Academy

Ryabtsev A.V.

Kirov Military Medical Academy;
Konstantinov Petersburg Institute of Nuclear Physics of the National Research Center «Kurchatov Institute»;
National Research Center «Kurchatov Institute»

Received:

09.09.2021

Accepted:

15.09.2021

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