The article contains curriculum vitae of W. Griesinger and an analysis of the clinical-psychopathological approach developed by him for studying illnesses and their systematization. The stages of psychosis’ progression in dynamics are shown. A clinical description of primary emerged dementia made by W. Griesinger as well as a description of the status of Grubelsucht, first discovered by the psychiatrist, are presented. The article emphasizes W. Griesinger’ priority in the determination of reflexes’ exclusive role in the appearance and further development of all types of mental disorders. W. Griesinger’s conviction in the necessity of more close interaction of neurology and psychiatry is highlighted.