The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2026
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Iurov I.Iu.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva;
Moskovskiĭ NII pediatrii i detskoĭ khirurgii Minzdrava RF, Moskva;
Moskovskiĭ gorodskoĭ psikhologo-pedagogicheskiĭ universitet, Moskva

Vorsanova S.G.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva;
Moskovskiĭ NII pediatrii i detskoĭ khirurgii Minzdrava RF, Moskva;
Moskovskiĭ gorodskoĭ psikhologo-pedagogicheskiĭ universitet, Moskva

Kurinnaia O.S.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva;
Moskovskiĭ NII pediatrii i detskoĭ khirurgii Minzdrava RF, Moskva;
Moskovskiĭ gorodskoĭ psikhologo-pedagogicheskiĭ universitet, Moskva

Kolotiĭ A.D.

FGBU "Moskovskiĭ NII pediatrii i detskoĭ khirurgii" Minzdrava Rossii, Moskva;
FGBU "Nauchnyĭ tsentr psikhicheskogo zdorov'ia" RAMN, Moskva

Demidova I.A.

FGBU "Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN", Moskva;
FGBU "Moskovskiĭ NII pediatrii i detskoĭ khirurgii Minzdrava Rossii", Moskva;
Moskovskiĭ gorodskoĭ psikhologo-pedagogicheskiĭ universitet, Moskva

Kravets V.S.

FGBU "Moskovskiĭ NII pediatrii i detskoĭ khirurgii" Minzdrava Rossii, Moskva;
FGBU "Nauchnyĭ tsentr psikhicheskogo zdorov'ia" RAMN, Moskva;
Moskovskiĭ gorodskoĭ psikhologo-pedagogicheskiĭ universitet, Moskva

Iurov Iu.B.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva;
Moskovskiĭ NII pediatrii i detskoĭ khirurgii Minzdrava RF, Moskva;
Moskovskiĭ gorodskoĭ psikhologo-pedagogicheskiĭ universitet, Moskva

The use of molecular cytogenetic and cytogenetic techniques for the diagnosis of Prader-Willi and Angelman syndroms

Authors:

Iurov I.Iu., Vorsanova S.G., Kurinnaia O.S., Kolotiĭ A.D., Demidova I.A., Kravets V.S., Iurov Iu.B.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2014;114(1): 49‑53

Read: 14945 times

Download PDF (RU)
Contact the author
Table of contents

THE USE OF MOLECULAR CYTOGENETIC AND CYTOGENETIC TECHNIQUES FOR THE DIAGNOSIS OF PRADER-WILLI AND ANGELMAN SYNDROMS
THE USE OF MOLECULAR CYTOGENETIC AND CYTOGENETIC TECHNIQUES FOR THE DIAGNOSIS OF PRADER-WILLI AND ANGELMAN SYNDROMS

To cite this article:

Iurov IIu, Vorsanova SG, Kurinnaia OS, Kolotiĭ AD, Demidova IA, Kravets VS, Iurov IuB. The use of molecular cytogenetic and cytogenetic techniques for the diagnosis of Prader-Willi and Angelman syndroms. S.S. Korsakov Journal of Neurology and Psychiatry. 2014;114(1):49‑53. (In Russ.)

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
Sleep diso­rders in imprinting diso­rders. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(5-2):75-80
Genome instability of the cholera agent: role in the evolution of pathogenicity, drug resi­stance and adaptation to a changing envi­ronment. Mole­cular Gene­tics, Microbiology and Viro­logy. 2025;(2):3-13
Coro­naviruses in human pathophysiology: a brief history of the COVID-19 pandemic. Mole­cular Gene­tics, Microbiology and Viro­logy. 2025;(4-2):55-63
Abstract:

We examined 30 patients with a presumptive diagnosis of Prader-Willi and Angelman syndromes. In four patients, 15q11.2-q13 deletions were identified by cytogenetic techniques. The FISH method was used to study eight patients, in five of them microdeletions were also confirmed. High-resolution comparative genomic hybridization (CGH) and comparative genomic hybridization using DNA microarrays (array CGH) allowed to find 15q11.2-q13 deletions in five patients. These cases demonstrate the need for high-resolution post-genomic technologies (array CGH - molecular karyotyping) in the combination with classical cytogenetic and molecular cytogenetic techniques.

Keywords:

Angelman syndrome
Prader-Willi syndrome
genetic diagnostics
genome
DNA microarray
molecular karyotyping
fluorescent hybridization in situ
genomic and chromosomal abnormalities

Authors:

Iurov I.Iu.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva;
Moskovskiĭ NII pediatrii i detskoĭ khirurgii Minzdrava RF, Moskva;
Moskovskiĭ gorodskoĭ psikhologo-pedagogicheskiĭ universitet, Moskva

Vorsanova S.G.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva;
Moskovskiĭ NII pediatrii i detskoĭ khirurgii Minzdrava RF, Moskva;
Moskovskiĭ gorodskoĭ psikhologo-pedagogicheskiĭ universitet, Moskva

Kurinnaia O.S.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva;
Moskovskiĭ NII pediatrii i detskoĭ khirurgii Minzdrava RF, Moskva;
Moskovskiĭ gorodskoĭ psikhologo-pedagogicheskiĭ universitet, Moskva

Kolotiĭ A.D.

FGBU "Moskovskiĭ NII pediatrii i detskoĭ khirurgii" Minzdrava Rossii, Moskva;
FGBU "Nauchnyĭ tsentr psikhicheskogo zdorov'ia" RAMN, Moskva

Demidova I.A.

FGBU "Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN", Moskva;
FGBU "Moskovskiĭ NII pediatrii i detskoĭ khirurgii Minzdrava Rossii", Moskva;
Moskovskiĭ gorodskoĭ psikhologo-pedagogicheskiĭ universitet, Moskva

Kravets V.S.

FGBU "Moskovskiĭ NII pediatrii i detskoĭ khirurgii" Minzdrava Rossii, Moskva;
FGBU "Nauchnyĭ tsentr psikhicheskogo zdorov'ia" RAMN, Moskva;
Moskovskiĭ gorodskoĭ psikhologo-pedagogicheskiĭ universitet, Moskva

Iurov Iu.B.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Moskva;
Moskovskiĭ NII pediatrii i detskoĭ khirurgii Minzdrava RF, Moskva;
Moskovskiĭ gorodskoĭ psikhologo-pedagogicheskiĭ universitet, Moskva

Close metadata

Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.