Efficacy and tolerability of short courses of nonsteroid anti-inflammatory drugs in the treatment of dorsalgia: results of the comparative study

Koval'chuk V.V.; Efimov M.A.

doi:https://doi.org/

Koval'chuk V.V.

Gorodskaia bol'nitsa #38 im. N.A. Semashko, Sankt-Peterburg;
Lomonosovskaia tsentral'naia raĭonnaia bol'nitsa, Lomonosov

Efimov M.A.

Gorodskaia bol'nitsa #38 im. N.A. Semashko, Sankt-Peterburg;
Lomonosovskaia tsentral'naia raĭonnaia bol'nitsa, Lomonosov

Efficacy and tolerability of short courses of nonsteroid anti-inflammatory drugs in the treatment of dorsalgia: results of the comparative study

Authors:

Koval'chuk V.V., Efimov M.A.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2010;110(1): 55‑58

Read: 70223 times

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Koval'chuk VV, Efimov MA. Efficacy and tolerability of short courses of nonsteroid anti-inflammatory drugs in the treatment of dorsalgia: results of the comparative study. S.S. Korsakov Journal of Neurology and Psychiatry. 2010;110(1):55‑58. (In Russ.)

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)

Использование инфографики авторами научных работ

Close metadata

Recommended articles:

Combined treatment of patients with acute muscular tonic syndrome with dorsopathy. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(3):70-77

Contemporary concepts of the rational use of centrally acting skeletal muscle relaxants in the treatment of vertebrogenic dorsalgia. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(12):154-160

Comparative analysis of the effectiveness of modern physiotherapeutical methods of dorsalgia treatment. Problems of Balneology, Physiotherapy and Exercise Therapy. 2025;(2):35-44

Abstract:

Efficacy of different nonsteroid anti-inflammatory drugs (voltaren (diclofenac), movalis (meloxicam), nimesil (nimesulide) and xefocam (lornoxicam) in stopping the pain syndrome and normalization of motor activity was assessed in 140 patients with dorsalgia using the Visual Analogous Scale and the modified Waddel scale. Moreover, we suggest a method for calculating a treatment efficacy coefficient. The most effective drug in the treatment of back pain was xefocam (lornoxicam). Nimesil (nimesulide) was somewhat less effective. Other drugs did not reveal any significant effect. Xefocam was well-tolerated: adverse effects were rare compared to other drugs used in the study.

Keywords:

dorsalgia

xefocam (lornoxicam)

nimesil (nimesulide)

treatment efficacy coefficient

Authors:

Koval'chuk V.V.

Gorodskaia bol'nitsa #38 im. N.A. Semashko, Sankt-Peterburg;
Lomonosovskaia tsentral'naia raĭonnaia bol'nitsa, Lomonosov

Efimov M.A.

Gorodskaia bol'nitsa #38 im. N.A. Semashko, Sankt-Peterburg;
Lomonosovskaia tsentral'naia raĭonnaia bol'nitsa, Lomonosov

Close metadata

References:

Antipenko E.A., Anisimova L.M., Bazaeva E.A. i dr. Primenenie preparata Ksefokam pri ostroi vertebrogennoi dorsalgii. Ksefokam i bol'. Pod red. I.V. Leonenko. Copenhagen-Moscow 2004;49-50.
Veselovskii V.P. Prakticheskaya vertebronevrologiya i manual'naya terapiya. Riga 1991;344.
Voznesenskaya T.G. Lyumboishialgiya. Ksefokam i bol'. Pod red. I.V. Leonenko. Copenhagen-Moscow 2004;23-28.
Kamchatnov P.R. Sovremennye podkhody k vedeniyu bol'nykh s bol'yu v spine. Consilium Medicum 2004;8:557-561.
Karlov V.A. Terapiya nervnykh boleznei: Rukovodstvo dlya vrachei. M: Shag 1996;653.
Koval'chuk V.V. Printsipy organizatsii i effektivnost' razlichnykh metodov reabilitatsii bol'nykh posle insul'ta: Avtoref. dis. … d-ra med. nauk. St-Peterburg 2008;42.
Levin O.S. Diagnostika i lechenie nevrologicheskikh proyavlenii osteokhondroza pozvonochnika. Consilium Medicum 2004;8:547-555.
Lomakin A.I. Ostekhondroz pozvonochnika. Opyt primeneniya movasina pri bolevom sindrome. Trudnyi patsient 2007;11:26-28.
Nasonova V.A., Bagirova G.G. Bol' v nizhnei chasti spiny u podrostkov. Lechashchii vrach 2005;11:40-42.
Podchufarova E.V. Bol' v poyasnichno-krestsovoi oblasti: diagnostika i lechenie. Rus med zhurn 2004;10:581-584.
Popelyanskii Ya.Yu. Ortopedicheskaya nevrologiya (vertebronevrologiya). Rukovodstvo dlya vrachei. 3-e izd. M: MEDpress-inform 2003;672.
Prokhorov A.A., Makarov A.Yu., Turichin V.I. Osteokhondroz pozvonochnika s nevrologicheskimi oslozhneniyami. Klinicheskaya nevrologiya s osnovami mediko-sotsial'noi ekspertizy: Rukovodstvo dlya vrachei. Pod red. A.Yu. Makarova. St-Peterburg: Zolotoi vek 1998;27-68.
Khabirov F.A. Rukovodstvo po klinicheskoi nevrologii pozvonochnika. Kazan': Meditsina 2006;520.
Shmyrev V.I., Bobrova T.A. Opyt primeneniya ksefokama u patsientov s bolevymi sindromami pozvonochnika. Ksefokam i bol'. Pod red. I.V. Leonenko. Copenhagen-Moscow 2004;29-30.
Shtul'man D.R., Levin O.S. Nevrologiya: Spravochnik prakticheskogo vracha. 5-e izd. M: MEDpress-inform 2007;960.
Huskisson E.C. Measurement of pain. Lancet 1974;304:2:1127-1131.
Sies R., Bach G.L. Combinationstherapie (Diclofenac-Ampulten peus Diclofenac mil B-Vitaminen) bei Neuratiden und Neuralgien. Krankenhausarzt 1982;55:8:683-685.
Waddel G. The back pain revolution. Edinburg: Churchill Livingstone 1998;438.