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Romanov D.V.

I.M. Sechenov First Moscow State Medical University (Sechenov University);
Mental Health Research Center

Smulevich A.B.

Mental health research center;
Sechenov First Moscow State Medical University (Sechenov University)

Fadeev V.V.

I.M. Sechenov First Moscow State Medical University

Dmitrenko K.Iu.

Sechenov First Moscow State Medical University (Sechenov University)

Khaikina I.A.

Sechenov First Moscow State Medical University (Sechenov University)

Sadkova O.A.

Mental Health Research Center

Shamirian L.G.

Sechenov First Moscow State Medical University (Sechenov University)

Voronova E.I.

Mental health research center;
Sechenov First Moscow State Medical University (Sechenov University)

Hypochondriasis in Graves’ disease: the role of pathologic factors and clinical characteristics endocrinopathy

Authors:

Romanov D.V., Smulevich A.B., Fadeev V.V., Dmitrenko K.Iu., Khaikina I.A., Sadkova O.A., Shamirian L.G., Voronova E.I.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2023;123(4‑2): 28‑35

DOI: 10.17116/jnevro202312304228

Read: 2529 times

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Table of contents

HYPOCHONDRIASIS IN GRAVES’ DISEASE: THE ROLE OF PATHOLOGIC FACTORS AND CLINICAL CHARACTERISTICS ENDOCRINOPATHY
HYPOCHONDRIASIS IN GRAVES’ DISEASE: THE ROLE OF PATHOLOGIC FACTORS AND CLINICAL CHARACTERISTICS ENDOCRINOPATHY

To cite this article:

Romanov DV, Smulevich AB, Fadeev VV, et al. Hypochondriasis in Graves’ disease: the role of pathologic factors and clinical characteristics endocrinopathy. S.S. Korsakov Journal of Neurology and Psychiatry. 2023;123(4‑2):28‑35. (In Russ.)
https://doi.org/10.17116/jnevro202312304228

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

OBJECTIVE

Clinical qualification of hypochondriasis or illness anxiety disorder (IAD) in Graves’ disease (GD) and verification of associated personality and endocrinological factors.

MATERIAL AND METHODS

A sample consisted of 27 patients (25 female and 2 male, mean age 48.4 years) with GD and personality disorders (PDs). The patients were examined clinically and with interviews for the assessment of PD according to DSM-IV (SCID-II-PD) and the Short Health Anxiety Inventory (SHAI).

RESULTS

IAD was diagnosed in 8 cases (29.6%), of which the main study group was formed. The remaining 19 patients, who did not show signs of IAD, were assigned to the control group. In the main group, the average score on the SHAI «health anxiety» subscale was significantly higher (10.2 vs 4.8 points, p<0.05) corresponding to the clinical qualification of the condition as IAD. When assessing the frequency of categorical PDs, it was found that there were no affective PDs in the main group, likewise there were no anxiety cluster PDs in the control group (p<0.05). In turn, in the main group, PDs were characterized by such dimensions as the phenomena of psychopathological diathesis, reactive lability, neuropathy, which were not observed in the control group. The endocrinological factor that differed significantly in main and control groups was the frequency of recurrence of GD (75.0% vs, 40.1%, p<0.05).

CONCLUSION

Despite the generally relatively favourable prognosis of GD, there is a significant frequency of IAD, the key role in the formation of which is apparently played by the parameters of the premorbid characteristics, as well as GD recurrence.

Keywords:

Graves’ disease
Bazedov’s disease
diffuse toxic goiter
hypochondriasis
illness anxiety disorder
personality disorders

Authors:

Romanov D.V.

I.M. Sechenov First Moscow State Medical University (Sechenov University);
Mental Health Research Center

Smulevich A.B.

Mental health research center;
Sechenov First Moscow State Medical University (Sechenov University)

Fadeev V.V.

I.M. Sechenov First Moscow State Medical University

Dmitrenko K.Iu.

Sechenov First Moscow State Medical University (Sechenov University)

Khaikina I.A.

Sechenov First Moscow State Medical University (Sechenov University)

Sadkova O.A.

Mental Health Research Center

Shamirian L.G.

Sechenov First Moscow State Medical University (Sechenov University)

Voronova E.I.

Mental health research center;
Sechenov First Moscow State Medical University (Sechenov University)

Received:

25.11.2022

Accepted:

21.12.2022

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