Chronic endogenous depression of youth

Close metadata

OBJECTIVE

To identify psychopathological features of chronic endogenous depression that develops in youth and determine most significant diagnostic and prognostic criteria.

MATERIAL AND METHODS

Sixty-two male inpatients were examined who had suffered from a chronic depressive state over 2 — years in their youth (16—25 years old) and were treated at FSBSI MHRC clinic in 2008—2010. The exclusion criteria were the presence of psychotic episodes, severe deficiency symptoms, as well as clinically significant somatic, neurological and mental disorders that complicated the study. Clinical-psychopathological, psychometric (HDRS, SANS and SOPS) and statistical methods were used.

RESULTS AND CONCLUSION

Youth chronic endogenous depression is characterized by the dominance of symptoms of negative affectivity in their structure. In addition, there are disorders that differ from those of an affective spectrum. Based on the analysis of psychopathological characteristics of youth chronic endogenous depressions, two typological varieties are identified: unitary depressions (type I) and supplementary depressions (type II). Among type II depressions, 2 subtypes are distinguished: with neurosis-like and with psychopathic- like disorders. The presence of psychopathic disorders in the structure of depression is a prognostically unfavorable sign.

Keywords:

chronic depression

persistent depressive disorder

dysthymia

youth

Authors:

Kaleda V.G.

Mental Health Research Centre

SPIN RSCI: 9035-3290
Scopus AuthorID: 56765570100
ResearcherID: K-5466-2013
ORCID: 0000-0002-1209-1443

Migalina V.V.

Mental Health Research Centre

Received:

09.03.2021

Accepted:

26.03.2021

List of references:

Hölzel L, Härter M, Reese C, Kriston L. Risk factors for chronic depression — a systematic review. Journal of Affective Disorders. 2011;129(1-3):1-13. https://doi.org/10.1016/j.jad.2010.03.025
Murphy JA, Byrne GJ. Prevalence and correlates of the proposed DSM-5 diagnosis of chronic depressive disorder. Journal of Affective Disorders. 2012;139(2):172-180. https://doi.org/10.1016/j.jad.2012.01.033
Krylova ES, Beburishvili AA, Kaleda VG. Non-suicidal self-injury and its relation to suicidal behavior in youth patients with personality disorders. Suicidology. 2019;10(1):48-57. (In Russ.). https://doi.org/10.32878/suiciderus
Beburishvili AA, Zyablov VA, Kaleda VG. Clinical characteristics of autoagressive behavior in youth patients with continuous cycling of endogenous affective disorders. Mental Health of Children and Adolescent. 2018;2(18):82-86. (In Russ.). https://elibrary.ru/item.asp?id=34878910
Krylova ES, Kuleshov AA, Beburishvili AA, Kaleda VG. Auto-aggressive behavior in patients with narcissistic and borderline personality disorder in youth. Psihicheskoe Zdorov’e. 2020;12:37-47. (In Russ.).
Isometsä E. Suicidal behaviour in mood disorders — who, when, and why? The Canadian Journal of Psychiatry. 2014;59(3):120-130. https://doi.org/10.1177/070674371405900303
Dong M, Zeng LN, Lu L, Li XH, Ungvari GS, Ng CH, ChowI HI, Zhang L, Zhou Y, Xiang YT. Prevalence of suicide attempt in individuals with major depressive disorder: a meta-analysis of observational surveys. Psychological Medicine. 2019;49(10):1691-1704. https://doi.org/10.1017/S0033291718002301
Tsutsul’kovskaya MYa, Kopeyko GI, Oleychik IV, Vladimirova TV. Rol’ psikhobiologicheskikh kharakteristik yunosheskogo vozrasta v formirovanii klinicheskoy kartiny depressiy i osobennostyakh terapii. Psikhiatriya. 2003;5(5):21-28. (In Russ.). https://elibrary.ru/item.asp?id=18758271
Petrova NN. Optimizatsiya antidepressivnoy terapii. Obozrenie Psikhiatrii i Meditsinskoy Psikhologii im. V.M. Bekhtereva. 2013;2:83-96. (In Russ.). https://elibrary.ru/item.asp?id=20401783
Egger HL, Angold A. Common emotional and behavioral disorders in preschool children: presentation, nosology, and epidemiology. Journal of Child Psychology and Psychiatry. 2006;47(3-4):313-337. https://doi.org/10.1111/j.1469-7610.2006.01618.x
Hyde JS, Mezulis AH, Abramson LY. The ABCs of depression: integrating affective, biological, and cognitive models to explain the emergence of the gender difference in depression. Psychological Review. 2008;115(2):291. https://doi.org/10.1037/0033-295X.115. 2.291
Mazaeva NA, Kravchenko NE. The nosospecific and age-sex dependent peculiarities of adolescent depressions. Sovremennaya Terapiya v Psikhiatrii i Nevrologii. 2018;2:18-23. (In Russ.). https://elibrary.ru/item.asp?id=35134861
Asiri WA, Board A, Board S, Almaqbali M, Board O. Obsessive-Compulsive Disorder as a Part of Prodromal Schizophrenia. Bahrain Medical Bulletin. 2018;40(1):55-56. https://www.bahrainmedicalbulletin.com/MAR_2018/MAR2018_OCD.pdf
Jinnin R, Furukawa TA, Kawakami N, Miyake Y, Nishiyama Y, Okamoto Y,Shimoda H, Sugiura Y, Takagaki K, Takebayashi Y, Tanaka K, Yamamura T, Yamawaki S. PS228. Subthreshold depression persists and increases the risk for depression in late adolescence: a one-year cohort study. International Journal of Neuropsychopharmacology. 2016;19(1):83. https://doi.org/10.1093/ijnp/pyw043.228
Omelchenko MA. Negative symptoms at the prodromal stage of schizophrenia at a young age (current problems of diagnostics and treatment). V.M. Bekhterev Review of Psychiatry and Medical Psychology. 2019;(4-2):41-48. (In Russ.). https://doi.org/10.31363/2313-7053-2019-4-2-41-48
Rumyantsev AO, Omel’chenko MA, Meleshko TK, Kaleda VG. Youth depression with attenuated psychotic symptoms (clinical and psychological analysis). Psikhiatriya. 2018;78:64-72. (In Russ.).
Smulevich AB, Dubnitskaya EB. Actual problems of systematics of depression. Zhurnal Nevrologii i Psikhiatrii im. S.S. Korsakova. Spetsvypuski. 2012;112(11):11-20. (In Russ.). https://elibrary.ru/item.asp?id=18958747
Oleychik IV. Psikhopatologiya, tipologiya i nozologicheskaya otsenka yunosheskikh endogennykh depressiy (kliniko-katamnesticheskoe issledovanie). Zhurnal Nevrologii i Psikhiatrii im. S.S. Korsakova. 2011;111(2):10-18. (In Russ.). https://elibrary.ru/item.asp?id=16597152
Tsutsul’kovskaya MYa, Kopeyko GI, Oleychik IV, Vladimirova TV. Rol’ psikhobiologicheskikh kharakteristik yunosheskogo vozrasta v formirovanii klinicheskoy kartiny depressiy i osobennostyakh terapii. Psikhiatriya. 2003;5(5):21-28. (In Russ.). https://elibrary.ru/item.asp?id=18758271
Watson D, Clark LA. Negative affectivity: the disposition to experience aversive emotional states. Psychological Bulletin. 1984;96(3):465. https://pubmed.ncbi.nlm.nih.gov/6393179
Smulevich AB, Dubnitskaya EB. Actual problems of systematics of depression. Zhurnal Nevrologii i Psikhiatrii im. S.S. Korsakova. Spetsvypuski. 2012;112(11):11-20. (In Russ.). https://elibrary.ru/item.asp?id=18958747
Kaleda VG. Endogenous psychoses with a first episode at the juvenile age: course and outcome (follow-up study). Zhurnal Nevrologii i Psikhiatrii im. S.S. Korsakova. 2008;108(9):11-23. (In Russ.). https://www.elibrary.ru/item.asp?id=42912925

Close metadata