The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.
Kryukov A.I.
Sverzhevsky Research Institute of Clinical Otorhinolaryngology Moscow Department of Healthcare;
Department of Otorhinolaryngology Academician B.S. Preobrazhensky Medical Faculty of the Pirogov Russian National Medical Research University
Garov E.V.
Sverzhevsky Research Institute of Clinical Otorhinolaryngology Moscow Department of Healthcare;
Department of Otorhinolaryngology Academician B.S. Preobrazhensky Medical Faculty of the Pirogov Russian National Medical Research University
Zelikovich E.I.
Sverzhevsky Research Clinical Institute of Otorhinolaryngology
Zagorskaya E.E.
Sverzhevsky Research Institute of Clinical Otorhinolaryngology Moscow Department of Healthcare
Kaloshina A.S.
Sverzhevsky Research Institute of Clinical Otorhinolaryngology Moscow Department of Healthcare
Garova E.E.
Sverzhevsky Research Institute of Clinical Otorhinolaryngology Moscow Department of Healthcare
Panasova A.S.
Sverzhevsky Research Clinical Institute of Otorhinolaryngology
Kovtun O.V.
Sverzhevsky Research Clinical Institute of Otorhinolaryngology
Khublaryan A.G.
Sverzhevsky Research Clinical Institute of Otorhinolaryngology
Features and results of surgical rehabilitation of hearing loss in osteogenesis imperfecta
Journal: Russian Bulletin of Otorhinolaryngology. 2023;88(6): 5‑14
Views: 1173
Downloaded: 95
To cite this article:
Kryukov AI, Garov EV, Zelikovich EI, et al. . Features and results of surgical rehabilitation of hearing loss in osteogenesis imperfecta. Russian Bulletin of Otorhinolaryngology.
2023;88(6):5‑14. (In Russ.)
https://doi.org/10.17116/otorino2023880615
Osteogenesis imperfecta (OI) is a form of congenital osteoporosis. Depending on the type of OI, patients experience various types of hearing loss. Depending on the type and degree of hearing loss, various methods of hearing rehabilitation are used in this category of patients.
To evaluate the features and results of surgical rehabilitation of hearing loss in patients with osteogenesis imperfecta.
During the period from 2009 to 2022, 2221 primary stapedoplasty was performed in the department, of which 23 (1.04%) in 21 patients were performed in patients with OI. There were 14 women and 7 men. According to TPA, bilateral hearing loss was detected in 19 patients and unilateral in 2. Conductive hearing loss was observed in 9 cases and mixed — in 14. The average thresholds for bone conduction (BC) were 22.7±8.04 dB, and the bone-air interval (ABG) — 36.1±5.3 dB. According to CT of the temporal bones, all patients showed a bilateral and symmetrical decrease in the density of the auditory ossicles, and in 7 patients there were extensive areas of non-uniform decrease in the density of the bone labyrinth up to +500 — +1000 HU.21 patients underwent 23 operations: in 21 cases stapedoplasty with laser assistance and in 2 cases ossiculoplasty.
BC thresholds 6 months after surgery averaged 24.6±8.2 dB, and ABG — 12.1±2.9 dB. Closing of ABG ≤10 dB at spoken frequencies was detected in 30.5%, ABG ≤20 dB — in 95%. After 12 months or more after the operation, no change in the audiological parameters was noted.
Stapes surgery for conductive and mixed hearing loss in OI patients is functionally effective. The best results are achieved after therapy with bisphosphonates with preparations of sodium fluoride, calcium and vitamin D, performing the operation when the density of demineralization zones reaches 1000 HU and using laser assistance. Taking into account the demineralization of the bone structures of the temporal bone, it is recommended to use autocartilaginous stirrup prostheses to restore sound conduction or to cover the attachment area of other prostheses with autologous tissues to prevent necrosis of the long stalk of the incus and stabilize long-term functional results.
Authors:
Kryukov A.I.
Sverzhevsky Research Institute of Clinical Otorhinolaryngology Moscow Department of Healthcare;
Department of Otorhinolaryngology Academician B.S. Preobrazhensky Medical Faculty of the Pirogov Russian National Medical Research University
Garov E.V.
Sverzhevsky Research Institute of Clinical Otorhinolaryngology Moscow Department of Healthcare;
Department of Otorhinolaryngology Academician B.S. Preobrazhensky Medical Faculty of the Pirogov Russian National Medical Research University
Zelikovich E.I.
Sverzhevsky Research Clinical Institute of Otorhinolaryngology
Zagorskaya E.E.
Sverzhevsky Research Institute of Clinical Otorhinolaryngology Moscow Department of Healthcare
Kaloshina A.S.
Sverzhevsky Research Institute of Clinical Otorhinolaryngology Moscow Department of Healthcare
Garova E.E.
Sverzhevsky Research Institute of Clinical Otorhinolaryngology Moscow Department of Healthcare
Panasova A.S.
Sverzhevsky Research Clinical Institute of Otorhinolaryngology
Kovtun O.V.
Sverzhevsky Research Clinical Institute of Otorhinolaryngology
Khublaryan A.G.
Sverzhevsky Research Clinical Institute of Otorhinolaryngology
Received:
06.03.2023
Accepted:
03.07.2023
List of references:
Close metadata
Email Confirmation
An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.
Email Confirmation
Log in to the site using your account in one of the services
We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.