The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 101-59-87
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2024
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Avetisov K.S.

FGBU "NII glaznykh bolezneĭ" RAMN

Bakhchieva N.A.

Research Institute of Eye Diseases, 11 A, B, Rossolimo St., Moscow, Russia, 119021

Avetisov S.E.

FGBU "Nauchno-issledovatel'skiĭ institut glaznykh bolezneĭ" RAMN, Moskva

Novikov I.A.

Institute of Cardiology named after A.L. Myasnikov of National Medical Research Center for Cardiology, Moscow, Russia

Golovchenko A.V.

I.M. Sechenov First Moscow State Medical University, Department of Ophthalmology, 8-2 Trubetskaya St., Moscow, Russian Federation, 119991

Shitikova A.V.

International school 'Medicine of Future' of the Sechenov University, 8-2 Trubetskaya St., Moscow, Russian Federation, 119991

Atomic force microscopy in the study of anterior eye segment structures

Authors:

Avetisov K.S., Bakhchieva N.A., Avetisov S.E., Novikov I.A., Golovchenko A.V., Shitikova A.V.

More about the authors

Journal: Russian Annals of Ophthalmology. 2020;136(1): 103‑110

DOI: 10.17116/oftalma2020136011103

Views: 2550

Downloaded: 83

Download PDF (RU)
Contact the author
Table of contents

To cite this article:

Avetisov KS, Bakhchieva NA, Avetisov SE, Novikov IA, Golovchenko AV, Shitikova AV. Atomic force microscopy in the study of anterior eye segment structures. Russian Annals of Ophthalmology. 2020;136(1):103‑110. (In Russ.)
https://doi.org/10.17116/oftalma2020136011103

Подписка 2025 (Russian Annals of Ophthalmology)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
Mediasphera_Net
Close metadata

The application of atomic force microscopy (AFM) in ophthalmology is considered with respect of the classical anatomical division of the eye into anterior and posterior segments. The review presents the findings of published research studies that involved AFM as a method for assessing anatomical and functional condition of the structures of anterior eye segment. One significant line of research is related to the use of AFM technologies for evaluation of morphological and biomechanical characteristics of various parts of the eye lens. That topic draws interest due to the need of furthering the understanding of cataractogenesis, as well as the significance of the anatomical and functional characteristics of the lens capsule in the mechanism of accommodation and modern phaco surgery.

Keywords:

atomic force microscopy
anterior lens capsule
Young’s modulus of elasticity
phaco surgery

Authors:

Avetisov K.S.

FGBU "NII glaznykh bolezneĭ" RAMN

Bakhchieva N.A.

Research Institute of Eye Diseases, 11 A, B, Rossolimo St., Moscow, Russia, 119021

Avetisov S.E.

FGBU "Nauchno-issledovatel'skiĭ institut glaznykh bolezneĭ" RAMN, Moskva

Novikov I.A.

Institute of Cardiology named after A.L. Myasnikov of National Medical Research Center for Cardiology, Moscow, Russia

Golovchenko A.V.

I.M. Sechenov First Moscow State Medical University, Department of Ophthalmology, 8-2 Trubetskaya St., Moscow, Russian Federation, 119991

Shitikova A.V.

International school 'Medicine of Future' of the Sechenov University, 8-2 Trubetskaya St., Moscow, Russian Federation, 119991

List of references:

  1. 1.Maver U, Velnar T, Gaberscek M, Planinsek O, Finsgar M. Recent progressive use of atomic force microscopy in biomedical applications. TrAC Trends in Analytical Chemistry. 2016, 80:96–111. https://doi.org/10.1016/j.trac.2016.03.014
  2. 2.Seo Y, Jhe W. Atomic force microscopy an spectroscopy. IOP Publishing Ltd. 2008; 71(1). https://doi.org/10.1088/0034-4885/71/1/016101
  3. Last J Russell P, Nealey PF, Murphy CJ. The Applications of Atomic Force Microscopy to Vision Science. Investigative Ophthalmology & Visual Science. December 2010; 51: 6083–6094. https://doi.org/10.1167/0-5470. Atomic force microscopy-based force measurements on animal cells and tissues. Methods Cell Biol. 2015; 125:211–235.
  4. Efremov YM, Bagrov DV, Dubrovin EV, Shaitan KV, Yaminskii IV. Atomic force microscopy of animal cells: Advances and prospects. Biophysics. 2011; 56:257–267. https://doi.org/10.1134/s0006350911020096
  5. Nagao E, Dvorac JA. An integrated approach to the study of living cells by atomic force microscopy. J.Microsc. 1998; 191:8–19. https://doi.org/10.1046/j.1365-2818.1998.00344.x
  6. 7.Hu DH, Micic M, Klimishyn N, Suh YD, Lu HP. Correlated topographic and spectroscopic imaging by combined atomic force microscopy and optical microscopy. J. Luminescence. 2004; 107:4–12. https://doi.org/10.1016/j.jlumin.2003.12.045
  7. Kassies R, Van der Werf KO, Lenferink A, et al. Combined AFM and confocal fluorescence microscope for applications in bionanotechnology. J.Microsc. 2005; 217:109–116. https://doi.org/10.1111/j.0022-2720.2005.01428.x
  8. Callies C, Schon P, Liashkovich I, et al. Simultaneous mechanical stiffness and electrical potential measurements of living vascular endothelial cells using combined atomic force and epifluorescence microscopy. Nanotechnology. 2009; 20:175104. https://doi.org/10.1088/0957-4484/20/17/175104
  9. 10.Anderson MS. Locally enhanced Raman spectroscopy with an atomic force microscopy. Appl. Phys. Lett. 2000; 76:3130–3132. https://doi.org/10.1063/1.126546
  10. Anderson MS, Gaimari SD. Raman-atomic force microscopy of the ommatidial surfaces of dipteran compound eyes. J. Structural Biol. 2003; 142:364–368. https://doi.org/10.1016/S1047-8477(03)00026-1
  11. 12.Antunes A, Gozzo FV, Nakamura M, et al. Analysis of the healthy rabbit lens surface using MAC mode atomic force microscopy. Micron. 2007; 38:286–290. https://doi.org/
  12. Antunes A, Gozzo FV, Nakamura M, et al. Atomic force imaging of ocular tissue: morphological study of healthy and cataract lenses. In: Modern Research and Educational Topics in Microscopy. Badajoz. Spain; 2007:29–36.
  13. 14.Buzhynskyy N., Girmens JF, Faigle W, Scheuring S. Human cataract lens membrane an subnanometer resolution. J. Mol. Biol. 2007; 374:162–169. https://doi.org/10.1016/j.jmb.2007.09.022
  14. 15.Buzhynskyy N, Hite RK, Walz T, Scheuring S. The supramolecular architecture of junctional microdomains in native lens membranes. EMBO Rep. 2007; 8:51–55.
  15. 16.Mangenot S, Buzhynskyy N, Jaroslawski S, et al. Malformation of junctional microdomains in cataract lens membranes from a type II diabetes patient. Pflugers Arch. 2009; 457:1265–1274. https://doi.org/10.1007/s00424-008-0604-4
  16. 17.Sueiras VM, Moy VT, Ziebarth NM. Lens capsule structure assessed with atomic force microscopy. Molecular Vision. 2015; 21:316–323. PMID: 25814829
  17. Talu S, Sueiras VM, Moy VT, Ziebarth NM. Micromorphology of the anterior human Lens capsule. Molecular Vision. 2018; 24:902–912. PMID: 30713427
  18. Ziebarth NM, Wojcikiewicz EP, Manns F, Moy VT, Parel J-M. Atomic force microscopy measurements of lens elasticity in monkey eyes. Molecular Vision. 2007; 13:504–510. PMID: 17417612
  19. Ziebarth NM, Arrieta E, Feuer WJ, Manns F, Moy VT, Parel J-M. Primate lens capsule elasticity assessed atomic force microscopy. Exp. Eye Res. 2011; 92:490–494. https://doi.org/10.1016/j.exer.2011.03.008
  20. Tsaousis KT, Karagiannidis PG, Kopsachilis N, Simeonidis C, Tsinopoulos IT, Karagkiozaki V, Lamprogiannis LP, Logothetidis S. Measurements of elastic modulus for human anterior lens capsule with atomic force microscopy: the effect of loading force. Int. ophthalmol. 2014; 32:519–523. https://doi.org/10.1007/s10792-013-9846-z
  21. Haritoglou C, Mauell S, Schumann RG, Henrich PB, Wolf A, Kernt M, Benoit M. Increase in lens capsule stiffness caused by vital dyes. J. Cataract Refract. Surg. 2013; 39:1749–1752. https://doi.org/10.1016/j.jcrs.2013.02.057
  22. Choi S, Lee H-J, Cheong Y, Shin J-H, Jin K-H, Park H-K, Park Y-G. AFM Study for Morphological Characteristics and Biomechanical Properties of Human Anterior Lens Capsule. Scanning. 2012; 34:247–256. https://doi.org/10.1002/sca.21001
  23. Lua RM, Oertle P, Camenzind L, et al. Superior Rim Stability of the Lens Capsule Following Manual Over Femtosecond Laser Capsulotomy. Inv. Opthalmol.&Vis.Sci. 2016; 57:2839–2849. https://doi.org/10.1167/iovs.15-18355
  24. Avetisov K, Fedorov A, Novikov I. Light and scanning electron microscopy of anterior lens capsule following different capsulorhexis techniques. Vestnik oftal’mologii. 2015;131(6):4–10. (In Russ.). https://doi.org/10.17116/oftalma201513164-10
  25. Maier JW, Klaproth OK, Ostovic M, et al. Cell death and ultrasound morphology of femtosecond laser-assisted anterior capsulotomy. IOVS. February 2014; 55(2):893–898. https://doi.org/10.1167/iovs.13-13343
  26. Karuri NW, Lilienziek S, Teixeira FI, et al. Biological length scale topography enhances cell-substratum adhesion of human corneal epithelial cells. J. Cell Sci. 2004; 117:3153–3164. https://doi.org/10.1242/jcs.01146
  27. Diehl KA, Foley JD, Nealey PF, Murphy CJ. Nanoscale topography modulates corneal epithelial cell migration. J. Biomed. Mater Res. A. 2005; 75:603–611. https://doi.org/10.1002/jbm.a.30467
  28. Lilienziek S, Campbell S, Nealey PF, Murphy CJ. The scale of substratum topographic features modulates proliferation of corneal epithelial cells and corneal fibroblasts. J. Biomed. Mater Res. A. 2006; 79:185–192. https://doi.org/10.1002/jbm.a.30744
  29. Abrams GA, Schaus SS, Goodman SL, et al. Nanoscale topography of the corneal epithelium membrane and Descemet’s membrane of the human. Cornea. 2000; 19:57–64. https://doi.org/10.1097/00003226-200001000-00012
  30. Last JA, Liliensiek SJ, Nealey PF, Murphy CJ. Determining the mechanical properties of human corneal basement membranes with atomic force microscopy. J. Struct. Biol. 2009; 167:19–24. https://doi.org/10.1016/j.jsb.2009.03.012
  31. Lombardo M, Lombardo G, Carbone G, et al. Biomechanics of the anterior human corneal tissue investigated with atomic force microscopy. IOVS. February 2012; 53(2):1050–1057. https://doi.org/10.1167/iovs.11-8720
  32. Nogradi A, Hopp B, Revesz K, et al. Atomic force microscopy study of the human cornea following excimer laser keratectomy. Exp. Eye Res. 2000; 70:363–368. https://doi.org/10.1006/exer.1999.0795
  33. Lombardo M, De Santo MP, Lombardo G, Barberi R, Serrao S. Atomic force microscopy analysis of normal and photoablated porcine cornea. J. Biomech. 2006; 39:2719–2724. https://doi.org/10.1016/j.jbiomech.2005.08.013
  34. Matteini P, Sbrana F, Tiribilli B, Pini R. Atomic force microscopy and transmission electron microscopy analysis of low-temperature laser welding of the cornea. Lasers Med. Sci. 2009; 24:667–671. https://doi.org/10.1007/s10103-008-0617-4
  35. John T, Patel A, Vasavada A, et al. Effect of trypan blue on Descemet membrane elasticity. Cornea. 2016; 35(11):1401–1403. https://doi.org/10.1097/ICO.0000000000000986
  36. Seifert J, Hammer CM, Rheinlaender J, et al. Distribution of Young’s modulus in porcine corneas after Riboflavin/UVA-induced collagen cross-linking as measured by atomic force microscopy. PLoS ONE. 2014; 9(1):1–8. https://doi.org/10.1371/journal.pone.0088186
  37. Labate C, De Santo MP, Lombardo M, Lombardo G. Understanding of the viscoelastic response of the human corneal stroma induced by Riboflavin/UVA- cross-linking at the nano level. PLoS ONE. 2015; 10(4):1–14. https://doi.org/10.1371/journal.pone.0122868
  38. Dias J, Diaconis VF, Lorenzo M, et al. Corneal stromal elasticity and viscoelasticity assessed by atomic force microscopy after different cross linking protocols. Exp. Eye Res. 2015; 138:1–5. https://doi.org/10.1016/j.exer.2015.06.015
  39. Lombardo M, Pucci G, Lombardo G, Barberi R. Interaction of ultraviolet light with the cornea: clinical implications for corneal crosslinking. J. Cataract Refract. Surg. 2015; 41(2):446–459. https://doi.org/10.1016/j.jcrs.2014.12.013
  40. Berry M, McMaster TJ, Corfield AP, Miles MJ. Exploring the molecular adhesion of ocular mucins. Biomacromolecules. 2001; 2:498–503. https://doi.org/10.1021/bm000145y
  41. Round AN, Berry M, McMaster TJ, et al. Glicopolymer charge density determines conformation in human ocular mucin gene products: ay atomic force microscope study. J. Struct. Biol. 2004; 145:246–253. https://doi.org/10.1016/j.jsb.2003.10.029
  42. Round AN, Berry M, McMaster TJ, et al. The isolated MUC5AC gene product from human ocular mucin displays intramolecular conformational heterogeneity. Glicobiology. 2007; 17:578–585. https://doi.org/10.1093/glycob/cwm027

Close metadata

Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register


We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.