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Mazunin I.O.

Immanuel Kant Baltic Federal University, 14 Nevskogo St., Kaliningrad, Russian Federation, 236016

Volodko N.V.

University of Alberta, 116 St. and 85 Ave., Edmonton, AB, Canada, T6G 2R3

Leber hereditary optic neuropathy

Authors:

Mazunin I.O., Volodko N.V.

More about the authors

Journal: Russian Annals of Ophthalmology. 2018;134(2): 92‑97

DOI: 10.17116/oftalma2018134292-96

Read: 11231 times

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Table of contents

LEBER HEREDITARY OPTIC NEUROPATHY
LEBER HEREDITARY OPTIC NEUROPATHY

To cite this article:

Mazunin IO, Volodko NV. Leber hereditary optic neuropathy. Russian Annals of Ophthalmology. 2018;134(2):92‑97. (In Russ.)
https://doi.org/10.17116/oftalma2018134292-96

Подписка 2026 Вестник офтальмологии (Russian Annals of Ophthalmology)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Leber hereditary optic neuropathy is characterized by bilateral, painless loss of vision in children and young adults (generally up to 25 years old). Since its first description in 1871, the understanding of its etiology and pathogenesis has improved considerably. The article considers Leber neuropathy from the points of view of ophthalmology, neurology and molecular genetics, and presents data on experimental treatment methods, one of which is undergoing clinical trial.

Keywords:

Leber’s disease
mutations in mtDNA
gene therapy methods

Authors:

Mazunin I.O.

Immanuel Kant Baltic Federal University, 14 Nevskogo St., Kaliningrad, Russian Federation, 236016

Volodko N.V.

University of Alberta, 116 St. and 85 Ave., Edmonton, AB, Canada, T6G 2R3

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References:

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