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Razumova I.Iu.

FGBU "NII glaznykh bolezneĭ" RAMN, Moskva

Vorob'eva O.K.

FGBU "NII glaznykh bolezneĭ" RAMN

Safonova T.N.

FGBU "NII glaznykh bolezneĭ" RAMN, Moskva

Sheremet N.L.

FGBU "NII glaznykh bolezneĭ" RAMN

Éksarenko O.V.

Uchrezhdenie Rossiĭskoĭ akademii meditsinskikh nauk "NII glaznykh bolezneĭ" RAMN, Moskva

Features of clinical manifestations of the globe, adnexal and orbital sarcoidosis

Authors:

Razumova I.Iu., Vorob'eva O.K., Safonova T.N., Sheremet N.L., Éksarenko O.V.

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Journal: Russian Annals of Ophthalmology. 2013;129(2): 33‑38

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To cite this article:

Razumova IIu, Vorob'eva OK, Safonova TN, Sheremet NL, Éksarenko OV. Features of clinical manifestations of the globe, adnexal and orbital sarcoidosis. Russian Annals of Ophthalmology. 2013;129(2):33‑38. (In Russ.)

Подписка 2025 (Russian Annals of Ophthalmology)
 
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86 patients with verified diagnosis of sarcoidosis with globe, adnexa and orbit manifestations were observed. The age of the patients ranged from 21 to 43 years old (average 35,1±1,2 years), among them 25 males and 61 females with disease duration from 1 month till 12 years and 15 years follow-up. The study is based on different variants of globe, adnexal and orbital sarcoidosis. In our practice we observed sarcoidosis as a combination of several manifestations simultaneously. In 32 patients of 38 patients examined HLA-B-7, B-8, DR-2, DR-3, DR-15 were detected, that confirms genetic predisposition to sarcoidosis and determines the course of the disease. In 27 patients cellular and humoral immunity disbalance was found, that confirms the immune etiology of sarcoidosis as well. However the treatment of patients was pathogenic as the etiology of sarcoidosis is still unknown.

Keywords:

sarcoidosis
uveitis
lacrimal gland
cellular and humoral immunity
HLA antigens

Authors:

Razumova I.Iu.

FGBU "NII glaznykh bolezneĭ" RAMN, Moskva

Vorob'eva O.K.

FGBU "NII glaznykh bolezneĭ" RAMN

Safonova T.N.

FGBU "NII glaznykh bolezneĭ" RAMN, Moskva

Sheremet N.L.

FGBU "NII glaznykh bolezneĭ" RAMN

Éksarenko O.V.

Uchrezhdenie Rossiĭskoĭ akademii meditsinskikh nauk "NII glaznykh bolezneĭ" RAMN, Moskva

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