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Pigolkin Yu.I.

I.M. Sechenov First Moscow State Medical University (Sechenov University) Ministry of Health of Russia

Shigeev S.V.

Bureau of Forensic Medicine of the Moscow Department of Health

Denisova A.V.

Bureau of Forensic Medical Examination of the Department of Health of the City of Moscow

Natarova K.V.

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Krupin K.N.

Sechenov First Moscow State Medical University (Sechenov University)

Forensic medical assessment of lidocaine and bupivacaine systemic toxicity

Authors:

Pigolkin Yu.I., Shigeev S.V., Denisova A.V., Natarova K.V., Krupin K.N.

More about the authors

Journal: Forensic Medical Expertise. 2023;66(4): 62‑66

DOI: 10.17116/sudmed20236604162

Read: 12342 times

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Table of contents

FORENSIC MEDICAL ASSESSMENT OF LIDOCAINE AND BUPIVACAINE SYSTEMIC TOXICITY
FORENSIC MEDICAL ASSESSMENT OF LIDOCAINE AND BUPIVACAINE SYSTEMIC TOXICITY

To cite this article:

Pigolkin YuI, Shigeev SV, Denisova AV, Natarova KV, Krupin KN. Forensic medical assessment of lidocaine and bupivacaine systemic toxicity. Forensic Medical Expertise. 2023;66(4):62‑66. (In Russ.)
https://doi.org/10.17116/sudmed20236604162

Подписка 2026 Судебно-медицинская экспертиза (Forensic Medical Expertise)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Recommended articles:
Systemic toxi­city of local anesthetics. Clinical guidelines of the All-Russian public orga­nization «Federation of anesthesiologists and reanimatologists». Russian Journal of Anesthesiology and Reanimatology. 2025;(5):8-21
Abstract:

THE AIM OF THE STUDY

Was to assess the lidocaine and bupivacaine systemic toxicity in forensic medical practice. The number of patients’ clinical observations equal three with local anesthetic systemic toxicity (LAST) from the practice of forensic medical experts were studied, and a search of scientific publications for the last 5 years in PubMed database was conducted. The amount of publications, describing cases with LAST, equal four were selected. Differential diagnostic features between LAST and anaphylaxis were considered. The literature data about relationship between lidocaine’s concentration in the blood serum and clinical features are shown. The forensic medical assessment of LAST is proposed.

Keywords:

local anesthetics
local anesthetic systemic toxicity (LAST)
lidocaine
bupivacaine

Authors:

Pigolkin Yu.I.

I.M. Sechenov First Moscow State Medical University (Sechenov University) Ministry of Health of Russia

Shigeev S.V.

Bureau of Forensic Medicine of the Moscow Department of Health

Denisova A.V.

Bureau of Forensic Medical Examination of the Department of Health of the City of Moscow

Natarova K.V.

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Krupin K.N.

Sechenov First Moscow State Medical University (Sechenov University)

Received:

14.12.2022

Accepted:

07.02.2023

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References:

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