Role of Kraevsky cells in forensic histological diagnostics

Fedulova M.V.; Bogomolov D.V.; Kupriyanov D.D.; Safronova A.N.

doi:https://doi.org/10.17116/sudmed20236601155

Fedulova M.V.

Russian Center for Forensic Medical Examination

ORCID: 0000-0002-8787-2228

Bogomolov D.V.

Russian Center for Forensic Medicine

Kupriyanov D.D.

Russian Center for Forensic Medical Examination

ORCID: 0000-0003-2730-1797

Safronova A.N.

Russian Center of Forensic Medical Expertise

Role of Kraevsky cells in forensic histological diagnostics

Authors:

Fedulova M.V., Bogomolov D.V., Kupriyanov D.D., Safronova A.N.

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Journal: Forensic Medical Expertise. 2023;66(1): 55‑58

DOI: 10.17116/sudmed20236601155

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To cite this article:

Fedulova MV, Bogomolov DV, Kupriyanov DD, Safronova AN. Role of Kraevsky cells in forensic histological diagnostics. Forensic Medical Expertise. 2023;66(1):55‑58. (In Russ.)
https://doi.org/10.17116/sudmed20236601155

Подписка 2026 Судебно-медицинская экспертиза (Forensic Medical Expertise)

Использование инфографики авторами научных работ

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Abstract:

The study objective is to establish the role of light hepatocytes (Kraevsky cells) for forensic histological diagnosis of glycogen depletion in the liver due to various conditions, including shock. A standard histological examination of liver samples of persons who died from various causes was performed; routine staining with hematoxylin and eosin and additional staining by the PAS method was used. Histotopographic comparison of cross sections was performed to clarify the localization of light hepatocytes with different PAS staining results. It was shown that light hepatocytes have different morphological features, localization, and results of PAS staining, regardless of the cause of death, and are not related to glycogen depletion in them. Light hepatocytes (Kraevski cells) cannot be used as a sign of glycogen depletion and/or shock.

Keywords:

light hepatocytes

Kraevsky cells

glycogen

shock

histology

Authors:

Fedulova M.V.

Russian Center for Forensic Medical Examination

ORCID: 0000-0002-8787-2228

Bogomolov D.V.

Russian Center for Forensic Medicine

Kupriyanov D.D.

Russian Center for Forensic Medical Examination

ORCID: 0000-0003-2730-1797

Safronova A.N.

Russian Center of Forensic Medical Expertise

Received:

24.03.2022

Accepted:

13.04.2022

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