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Savchuk S.A.

Department of Special Laboratory Investigations, Federal state budgetary institution «Russian Centre of Forensic Medical Expertise», Ministry of Health of the Russia, Moscow, Russia, 125284;
Laboratory of Pharmacokinetics and Metabolomic Analysis, Institute of Translational Medicine and Biotechnology of I.M. Sechenov First Moscow State Medical University, Moscow, Russia, 119992

Shestakova K.M.

I.M. Sechenov First Moscow State Medical University, Moscow, Russia;
Verona University, PhD program in nanoscience and advanced technologies, Verona, Italy

Rizvanova L.N.

Nizhnevartovsk Psychoneurological Hospital, Nizhnevartovsk, Russia, 628615

Burmykin D.A.

Bruker Ltd., Moscow, Russia

Ovcharov M.V.

Bruker Ltd., Moscow, Russia

Mesonzhnik N.V.

Laboratory of Pharmacokinetics and Metabolic Analysis, Institute of Pharmacy and Translational Medicine of the Federal State Autonomous Educational Institution of Higher Education, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, 119991

Appolonova S.A.

Nizhnevartovsk Psychoneurological Hospital, Nizhnevartovsk, Russia, 628615

Fast HPLC-MS/MS screening method for identification of illegal drugs including new psychoactive substances and their metabolites in human urine

Authors:

Savchuk S.A., Shestakova K.M., Rizvanova L.N., Burmykin D.A., Ovcharov M.V., Mesonzhnik N.V., Appolonova S.A.

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Journal: Forensic Medical Expertise. 2020;63(2): 32‑40

DOI: 10.17116/sudmed20206302132

Read: 3911 times

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FAST HPLC-MS/MS SCREENING METHOD FOR IDENTIFICATION OF ILLEGAL DRUGS INCLUDING NEW PSYCHOACTIVE SUBSTANCES AND THEIR METABOLITES IN HUMAN URINE
FAST HPLC-MS/MS SCREENING METHOD FOR IDENTIFICATION OF ILLEGAL DRUGS INCLUDING NEW PSYCHOACTIVE SUBSTANCES AND THEIR METABOLITES IN HUMAN URINE

To cite this article:

Savchuk SA, Shestakova KM, Rizvanova LN, Burmykin DA, Ovcharov MV, Mesonzhnik NV, Appolonova SA. Fast HPLC-MS/MS screening method for identification of illegal drugs including new psychoactive substances and their metabolites in human urine. Forensic Medical Expertise. 2020;63(2):32‑40. (In Russ.)
https://doi.org/10.17116/sudmed20206302132

Подписка 2026 Судебно-медицинская экспертиза (Forensic Medical Expertise)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Aim of this study was to develop a fast screening method for identification of illegal drugs including new psychoactive substances and their metabolites in human urine by means of liquid chromatography mass-spectrometry HPLC-MS/MS screening method for identification of 138 psychoactive substances in urine was established, validated and tested. High-resolution mass-spectrometry was used for confirmation of the developed approach. The developed method was tested on 50 positive urine samples containing the target compounds, which proved reliability and accuracy of the established screening method.

Keywords:

new psychoactive substances
mass-spectrometry
screening method

Authors:

Savchuk S.A.

Department of Special Laboratory Investigations, Federal state budgetary institution «Russian Centre of Forensic Medical Expertise», Ministry of Health of the Russia, Moscow, Russia, 125284;
Laboratory of Pharmacokinetics and Metabolomic Analysis, Institute of Translational Medicine and Biotechnology of I.M. Sechenov First Moscow State Medical University, Moscow, Russia, 119992

Shestakova K.M.

I.M. Sechenov First Moscow State Medical University, Moscow, Russia;
Verona University, PhD program in nanoscience and advanced technologies, Verona, Italy

Rizvanova L.N.

Nizhnevartovsk Psychoneurological Hospital, Nizhnevartovsk, Russia, 628615

Burmykin D.A.

Bruker Ltd., Moscow, Russia

Ovcharov M.V.

Bruker Ltd., Moscow, Russia

Mesonzhnik N.V.

Laboratory of Pharmacokinetics and Metabolic Analysis, Institute of Pharmacy and Translational Medicine of the Federal State Autonomous Educational Institution of Higher Education, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, 119991

Appolonova S.A.

Nizhnevartovsk Psychoneurological Hospital, Nizhnevartovsk, Russia, 628615

Close metadata

References:

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