The use of extractive freezing-out at the stage of preliminary preparation of bioprobes in GC-MS chemico-toxicological analysis

Bekhterev V.N.; Gavrilova S.N.; Shipanov I.N.

doi:https://doi.org/10.17116/sudmed20196206153

Bekhterev V.N.

Sochi State University, Sochi, Russia, 354000;
Krasnodar Bureau of Forensic Medical Expertise №2, Ministry of Health of the Krasnodar Region, Sochi, Russia, 354000

Gavrilova S.N.

Krasnodar Bureau of Forensic Medical Expertise №2, Ministry of Health of the Krasnodar Region, Sochi, Russia, 354000

Shipanov I.N.

Krasnodar Bureau of Forensic Medical Expertise №2, Ministry of Health of the Krasnodar Region, Sochi, Russia, 354000

The use of extractive freezing-out at the stage of preliminary preparation of bioprobes in GC-MS chemico-toxicological analysis

Authors:

Bekhterev V.N., Gavrilova S.N., Shipanov I.N.

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Journal: Forensic Medical Expertise. 2019;62(6): 53‑57

DOI: 10.17116/sudmed20196206153

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To cite this article:

Bekhterev VN, Gavrilova SN, Shipanov IN. The use of extractive freezing-out at the stage of preliminary preparation of bioprobes in GC-MS chemico-toxicological analysis. Forensic Medical Expertise. 2019;62(6):53‑57. (In Russ.)
https://doi.org/10.17116/sudmed20196206153

Подписка 2026 Судебно-медицинская экспертиза (Forensic Medical Expertise)

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Abstract:

The authors propose a new express method of low-temperature sample preparation based on the use of extractive freezing-out combined with a sample centrifugation as a stage of a preliminary preparation of a biological object (cadaveric liver, kidneys). The method made it possible to minimize sufficiently the so-called chemical noise of endogenous coextractive substances and to improve sufficiently the conditions of the GC-MS method.

Keywords:

liver

kidney

sample preparation

extractive freezing-out

GC-MS

Authors:

Bekhterev V.N.

Sochi State University, Sochi, Russia, 354000;
Krasnodar Bureau of Forensic Medical Expertise №2, Ministry of Health of the Krasnodar Region, Sochi, Russia, 354000

Gavrilova S.N.

Krasnodar Bureau of Forensic Medical Expertise №2, Ministry of Health of the Krasnodar Region, Sochi, Russia, 354000

Shipanov I.N.

Krasnodar Bureau of Forensic Medical Expertise №2, Ministry of Health of the Krasnodar Region, Sochi, Russia, 354000

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References:

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