The aspects of the molecular-genetic investigations of human hair depending on its morphological characteristics. I. Prognostic screening

Aleksandrova V.Yu.; Bogatyreva E.A.; Kuklev M.Iu.; Lapenkov M.I.; Plakhina N.V.

doi:https://doi.org/10.17116/sudmed20196201113

Aleksandrova V.Yu.

Institute of Criminalistics, Centre for Special Techniques, Russian Federal Security Service, Moscow, Russia, 101000

Bogatyreva E.A.

Institute of Criminal Science, Centre of Special Technologies, Federal Security Service of the Russia, Moscow, Russia, 101000

Kuklev M.Iu.

Institut kriminalistiki Tsentra spetsial'noĭ tekhniki FSB Rossii, Moskva

Lapenkov M.I.

Institut kriminalistiki Tsentra spetsial'noĭ tekhniki FSB Rossii, Moskva

Plakhina N.V.

Institut kriminalistiki Tsentra spetsial'noĭ tekhniki FSB Rossii, Moskva

The aspects of the molecular-genetic investigations of human hair depending on its morphological characteristics. I. Prognostic screening

Authors:

Aleksandrova V.Yu., Bogatyreva E.A., Kuklev M.Iu., Lapenkov M.I., Plakhina N.V.

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Journal: Forensic Medical Expertise. 2019;62(1): 13‑16

DOI: 10.17116/sudmed20196201113

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To cite this article:

Aleksandrova VYu, Bogatyreva EA, Kuklev MIu, Lapenkov MI, Plakhina NV. The aspects of the molecular-genetic investigations of human hair depending on its morphological characteristics. I. Prognostic screening. Forensic Medical Expertise. 2019;62(1):13‑16. (In Russ.)
https://doi.org/10.17116/sudmed20196201113

Подписка 2026 Судебно-медицинская экспертиза (Forensic Medical Expertise)

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Abstract:

The objective of the present work was to develop the method for the selection of hairs suitable for the molecular-genetic investigation of nuclear DNA. It was proposed to distinguish between five groups of hair depending on its growth phase, the presence or absence of epithelial tissues at the root terminus. An algorithm was developed for carrying out prognostic screening including the morphological and cytomorphological investigations the results of which can be used to evaluate the possibility for further genotyping.

Keywords:

human hair

anagen

catagen

telogen

hematoxylin

DAPI

genotyping

Authors:

Aleksandrova V.Yu.

Institute of Criminalistics, Centre for Special Techniques, Russian Federal Security Service, Moscow, Russia, 101000

Bogatyreva E.A.

Institute of Criminal Science, Centre of Special Technologies, Federal Security Service of the Russia, Moscow, Russia, 101000

Kuklev M.Iu.

Institut kriminalistiki Tsentra spetsial'noĭ tekhniki FSB Rossii, Moskva

Lapenkov M.I.

Institut kriminalistiki Tsentra spetsial'noĭ tekhniki FSB Rossii, Moskva

Plakhina N.V.

Institut kriminalistiki Tsentra spetsial'noĭ tekhniki FSB Rossii, Moskva

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References:

Harding H, Rogers G. Physiology and growth of human hair. In: Robertson J eds. Forensic Examination of Hair. London: Taylor & Francis. 1999;40-46. https://doi.org/10.1201/9780203483527
Linch CA, Smith SL, Prahlow JA. Evaluation of the human hair root for DNA typing subsequent to microscopic comparison. Journal Forensic Science. 1998;43(2):305-314. https://doi.org/10.1520/JFS16137J
Kouichi K, Kanako Y, Hideaki M, Hiroaki S, Hajime S. Hair root morphology and STR typing. Japanese Journal of Forensic Science and Technology. 2006;11(1):113-124.
Bourguignon L, Hoste B, Boonen T, Vits K, Hubrecht F. A fluorescent microscopy-screening test for efficient STR-typing of telogen hair roots. Forensic Science International: Genetics. 2008;3(1):27-31. https://doi.org/10.1016/j.fsigen.2008.08.006
Edson J, Brooks E, McLaren C, Robertson J, McNevin D, Cooper A, Austin J. A quantitative assessment of a reliable screening technique for the STR analysis of telogen hair roots. Forensic Science International: Genetics. 2013;7:180-188. https://doi.org/10.1016/j.fsigen.2012.10.001
Boonen T, Vits K, Hoste B, Hubrecht F. The visualization and quantification of cell nuclei in telogen hair roots by fluorescence microscopy, as a pre-DNA analysis assessment. Forensic Science International: Genetics Supplement Series. 2008;1:16-18. https://doi.org/10.1016/j.fsigss.2007.10.098
Roux C, Brooks L, Masaki L, Lennard C, Robertson J. Discrimination of human hairs using color measurements and digital microscopy. Paper presented at: trace evidence symposium. Sidney 2009; August 2-7.
Lepez T, Vandewoestyne M, Van Hoofstat D, Deforce D. Fast nuclear staining of head hair roots as a screening method for successful STR analysis in forensics. Forensic Science International: Genetics. 2014;13:191-194. https://doi.org/10.1016/j.fsigen.2014.08.003