The peculiarities of the comprehensive study of buprenorphine

Lobacheva G.K.; Simonov E.A.; Kuzovlev V.Yu.; Kairgaliev D.V.; Gavrilin Yu.V.; Atroshchenko Yu.M.

doi:https://doi.org/10.17116/sudmed201760230-35

Lobacheva G.K.

Volgograd Academy of the Russian Ministry of Internal Affairs, Volgograd, Russia, 400089

Simonov E.A.

GBOU VPO "Kurskiĭ gosudarstvennyĭ meditsinskiĭ universitet"

Kuzovlev V.Yu.

D.I. Mendeleev Chemical and Technological University, Moscow, Russia, 125047

Kairgaliev D.V.

Volgograd Academy of the Russian Ministry of Internal Affairs, Volgograd, Russia, 400089

Gavrilin Yu.V.

Research Institute of the Federal Service of the Execution of Sentences of the Russian Federation, Moscow, Russia, 125130

Atroshchenko Yu.M.

K.N. Tolstoy Tula State Pedagogical University, Tula, Russia, 300026

The peculiarities of the comprehensive study of buprenorphine

Authors:

Lobacheva G.K., Simonov E.A., Kuzovlev V.Yu., Kairgaliev D.V., Gavrilin Yu.V., Atroshchenko Yu.M.

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Journal: Forensic Medical Expertise. 2017;60(2): 30‑35

DOI: 10.17116/sudmed201760230-35

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To cite this article:

Lobacheva GK, Simonov EA, Kuzovlev VYu, Kairgaliev DV, Gavrilin YuV, Atroshchenko YuM. The peculiarities of the comprehensive study of buprenorphine. Forensic Medical Expertise. 2017;60(2):30‑35. (In Russ.)
https://doi.org/10.17116/sudmed201760230-35

Подписка 2026 Судебно-медицинская экспертиза (Forensic Medical Expertise)

Использование инфографики авторами научных работ

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Abstract:

The authors describe the methods of pharmaceutical and criminalistics analysis that are finding the increasingly wider application for the drug expertise (identification) and elucidation of the circumstances conducive to the commission of an offence. The special emphasis is laid on the buprenorphine studies with the use of the colour chemical reactions, thin-layer chromatography, gas chromatographic analysis, high-performance liquid chromatography, IR spectrometry, and other modern techniques. The methods based on the recent achievements in pharmaceutical and criminalistics sciences can be employed in the activities intended to control the illegal drug circulation. Moreover, they may be of importance for obtaining valuable information about the actions of the persons involved in the trafficking or synthesis (production) of the prohibited substances after they are brought to criminal responsibility and/or appear before the court.

Keywords:

buprenorphine

identification

comprehensive investigation

IR spectrometry

chromatography-mass spectrometric analysis

Authors:

Lobacheva G.K.

Volgograd Academy of the Russian Ministry of Internal Affairs, Volgograd, Russia, 400089

Simonov E.A.

GBOU VPO "Kurskiĭ gosudarstvennyĭ meditsinskiĭ universitet"

Kuzovlev V.Yu.

D.I. Mendeleev Chemical and Technological University, Moscow, Russia, 125047

Kairgaliev D.V.

Volgograd Academy of the Russian Ministry of Internal Affairs, Volgograd, Russia, 400089

Gavrilin Yu.V.

Research Institute of the Federal Service of the Execution of Sentences of the Russian Federation, Moscow, Russia, 125130

Atroshchenko Yu.M.

K.N. Tolstoy Tula State Pedagogical University, Tula, Russia, 300026

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References:

Lebedeva MV, Kononova SV, Vvedenskaya ES, Baranov DE. Pharmacotherapeutic characteristics of opioids used for the treatment of chronic pain syndrome of cancer patients. Meditcinskii almanakh. 2014;5(35):152-155. (In Russ.).
Gvalani S, Yashod S. Chapter-22 Postoperative Analgesia for Cardiac Surgical Patient. Cardiac Anesthesia: Practical Aspects. New Delhi — London — Philadelphia — Panama: Jaypee Medical. 2015;301-308. doi:10.5005/jp/books/12508_23
Phillips KA, Preston KL. Buprenorphine in Maintenance Therapy. In: Handbook of Methadone Prescribing and Buprenorphine Therapy. New York: Springer. 2013;139-162. doi: 10.1007/978-1-4614-6974-2_11
Wiegrebe W. The International Pharmacopoeia. 3rd. Edition. V. 4, WHO Genf, XV + 343 S., S 76.50. Archiv Der Pharmazie. 1994;327(11):754-754. doi: 10.1002/ardp.19943271119
U.S. Patent 3433791. Endoethano nor-oripavines and nor thebaines. K.W. Bentley. Mar, 18, 1969.
Degenhardt L, Larney S, Kimber J, Gisev N, Farrell M, Dobbins T, Burns L. The impact of opioid substitution therapy on mortality post‐release from prison: retrospective data linkage study. Addiction. 2014;109(8):1306-1317. doi: 10.1111/add.12536
Seldén T, Ahlner J, Druid H, Kronstrand R. Toxicological and pathological findings in a series of buprenorphine related deaths. Possible risk factors for fatal outcome. Forensic Science International. 2012;220(1-3):284-290. doi: 10.1016/j.forsciint.2012.03.016
Automated Information Retrieval System AIPSIN-ANTIDRUGS with «AIPSIN.3170» (4543 Mb). Minsk: Belhard Group (DVD). 2014. (In Russ.).
Olsen Y, Sharfstein JM. Confronting the Stigma of Opioid Use Disorder and Its Treatment. JAMA. 2014;311(14):1393-1394. doi: 10.1001/jama.2014.2147
Jordan S. British Pharmacopoeia. Nursing Standard. 2011;25(46):31-31. doi: 10.7748/ns2011.07.25.46.31.b1235
Stippler E, Kopp S, Dressman JB. Comparison of US Pharmacopeia Simulated Intestinal Fluid TS (without pancreatin) and Phosphate Standard Buffer pH 6.8, TS of the International Pharmacopoeia with Respect to Their Use in In Vitro Dissolution Testing. Dissolution Technologies. 2004;11(2):6-10. doi: 10.14227/dt110204p6
Gosudarstvennaia farmakopeia Ukrainy. Ukrainskii nauchnyi farmakopeinyi tcentr kachestva lekarstvennykh sredstv. Kharkov. 2008. (In Russ.).
Moffat AC. Сlarke’s Isolation and Identification of Drugs. 2-nd Ed. London: The Pharmaceutical Press. 1986. doi: 10.1111/j.2042-7158.1986.tb03392.x
Barceloux DG. Medical toxicology of drug abuse: synthesized chemicals and psychoactive plants. John Wiley & Sons. 2012. doi: 10.1002/9781118105955
Vinarskii V, Yurchenko R, Kovalenko A, Kuzovlev V, Gladirev V. Mass-spektrometriia i khromato-mass-spektralnyi analiz. Moscow: D. Mendeleev University of Chemical Technology of Russia. 2013. (In Russ.).
Huang Y-T, Tsai T-R, Cheng C-J, Cham T-M, Lai T-F, Chuo W-H. Formulation Design of an HPMC-Based Sustained Release Tablet for Pyridostigmine Bromide as a Highly Hygroscopic Model Drug and its In Vivo/In Vitro Dissolution Properties. Drug Development and Industrial Pharmacy. 2007;33(11):1183-1191. doi: 10.1080/03639040701377334
Machara A, Werner L, Endoma-Arias MA, Cox DP, Hudlicky T. Improved Synthesis of Buprenorphine from Thebaine and/or Oripavine via Palladium-Catalyzed N-Demethylation/Acylation and/or Concomitant O-Demethylation. Adv Synth Catal. 2012;354(4):613-626. doi: 10.1002/adsc.201100807