Method of multilayer assembly as alternative to antibacterial coverings of medicobiological implants

Ospanova A.K.; Omarova R.A.; Abdurazakov U.A.; Zhartybaev R.N.; Iskakova M.K.; Savdenbekova B.E.; Amkhadova M.A.

doi:https://doi.org/10.17116/stomat20169519-13

Ospanova A.K.

Department of Chemistry and Chemical Technology, Al-Farabi Kazakh National University, Almaty, Kazakhstan

Omarova R.A.

Kazakh National Medical University. SD Asfendiyarov, Almaty, Kazakhstan

Abdurazakov U.A.

Department of Traumatology and Orthopedics Almaty Kazakh Medical University of Continuing Education

Zhartybaev R.N.

Kazakh National Medical University. SD Asfendiyarov, Almaty, Kazakhstan

Iskakova M.K.

Kazakh National Medical University. SD Asfendiyarov, Almaty, Kazakhstan

Savdenbekova B.E.

Department of Chemistry and Chemical Technology, Al-Farabi Kazakh National University, Almaty, Kazakhstan

Amkhadova M.A.

Moscow Regional Research and Clinical Institute, Moscow, Russia, 129110

Method of multilayer assembly as alternative to antibacterial coverings of medicobiological implants

Authors:

Ospanova A.K., Omarova R.A., Abdurazakov U.A., Zhartybaev R.N., Iskakova M.K., Savdenbekova B.E., Amkhadova M.A.

More about the authors

Journal: Stomatology. 2016;95(1): 9‑13

DOI: 10.17116/stomat20169519-13

Read: 1012 times

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Ospanova AK, Omarova RA, Abdurazakov UA, Zhartybaev RN, Iskakova MK, Savdenbekova BE, Amkhadova MA. Method of multilayer assembly as alternative to antibacterial coverings of medicobiological implants. Stomatology. 2016;95(1):9‑13. (In Russ.)
https://doi.org/10.17116/stomat20169519-13

Подписка 2026 Стоматология (Stomatology)

Использование инфографики авторами научных работ

Close metadata

Abstract:

Department of Traumatology and Orthopedics Almaty Kazakh Medical University of Continuing Education; 4. Moscow Regional Research Clinical Institute, Russia Resume: in this report we present the results on the use of the method of layer-by-layer (LbL) for obtaining antimicrobial coatings for biomedical implants. As the substrates were used silicon titanium implants and silicon plate. For the obtaining multilayer coatings on the surfaces of the samples were used as the polycation - chitosan and polyanion - carboxymethylcellulose sodium. On the surface multilayer were deposited antibacterial preparations: Triclosan-2,4,4'trichloro-2' hydroxyphenyl ether, silver ions and iodine. Microbiological studies were conducted on the museum strains: E. coli, Candida and Staf. Preliminary antibacterial studies on these microorganisms showed high activity multilayer coating containing triclosan.

Keywords:

multilayer coating

triclosan

silver

iodine

implant

study

microorganisms

Authors:

Ospanova A.K.

Department of Chemistry and Chemical Technology, Al-Farabi Kazakh National University, Almaty, Kazakhstan

Omarova R.A.

Kazakh National Medical University. SD Asfendiyarov, Almaty, Kazakhstan

Abdurazakov U.A.

Department of Traumatology and Orthopedics Almaty Kazakh Medical University of Continuing Education

Zhartybaev R.N.

Kazakh National Medical University. SD Asfendiyarov, Almaty, Kazakhstan

Iskakova M.K.

Kazakh National Medical University. SD Asfendiyarov, Almaty, Kazakhstan

Savdenbekova B.E.

Department of Chemistry and Chemical Technology, Al-Farabi Kazakh National University, Almaty, Kazakhstan

Amkhadova M.A.

Moscow Regional Research and Clinical Institute, Moscow, Russia, 129110

Close metadata

References:

Lepilin A.V., Smirnov D.A. Osobennosti poverkhnosti dental'nogo implantata i ee vzaimodeistvie s okruzhayushchei kostnoi tkan'yu. Rossiiskii vestnik dental'noi implantologii. 2010;2:116-121.
Gribov L.A., Mushtakova S.P. Kvantovaya khimiya. M.: Gardariki; 1999.
Khel't'e Kh.-D., Zippl' V., Ron'yan D., Fol'kers G. Molekulyarnoe modelirovanie. Teoriya i praktika. Per. s angl. Pod red. Palyulina V.A. i Radchenko E.V. M.: BINOM. Laboratoriya znanii; 2010;318.
Qurrat-ul-Ain, Sharma S, Khuller GK, Garg SK. Alginate based oral drug delivery systems for tuberculosis: pharmacokinetics and therapeutic effects. Journal of Antitubercular Chemotherapy. 2003;51:931-938.
Soike T, Streff AK, Guan C, Ortega R, Tantawy M, Pino C. Engineering a material surface for drug delivery and imaging using layer-by-layer assembly of functionalized nanoparticles. Adv Mater. 2010;22:1392-1397.
Chaturbedy P, Jagadeesan D, Eswaramoorthy M. pH-Sensitive breathing of clay within the polyelectrolyte matrix. ACS Nano. 2010;4:5921-5929.
Mentbayeva AA, Ospanova AK, Tashmuhambetova ZH, Sokolova VV, Sukhishvili S. Polymer-metal complexes in polyelectrolyte multilayer films as catalysts for oxidation of toluene. Langmuir. 2012;28:11948-11955.
Moya S, Dahne L, Voigt A, Leporatti S, Donath E, Mtshwald H. Polyelectrolyte Multilayer Capsules Templated on Biological Cells - Core Oxidation Influences Layer Chemistry. Colloids Surf A. 2001;183:27-40.
Lvov Y, Ariga K, Ichinose I, Kunitake T. Assembly of multicomponent protein films by means of electrostatic layer-by-layer adsorption. J Am Chem Soc. 1995;17:6117-6123.
Albreksson T et al. Bakterial adhesion on commercially pure titanium and oxide disks an in vitro human studi. J Periodontol. 2004;2:292-296.