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Zikiryakhodzhaev A.D.

Hertsen Moscow Oncology Research Center;
Peoples’s Friendship University of Russia;
Sechenov First Moscow State Medical University

Manturova N.E.

Pirogov Russian National Research Medical University;
Institute of Plastic Surgery and Cosmetology

Mistakopylo F.N.

Frau Clinic 1

Sukhotko A.S.

Treatment and Rehabilitation Centre

Kovantsev S.D.

Treatment and Rehabilitation Centre

Duadze I.S.

Hertsen Moscow Oncology Research Center

Simultaneous reconstruction using endoprosthesis and lower deepithelialized flap in prophylactic mastectomy

Authors:

Zikiryakhodzhaev A.D., Manturova N.E., Mistakopylo F.N., Sukhotko A.S., Kovantsev S.D., Duadze I.S.

More about the authors

Journal: Plastic Surgery and Aesthetic Medicine. 2025;(2‑2): 16‑24

DOI: 10.17116/plast.hirurgia202502216

Read: 1049 times

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Table of contents

SIMULTANEOUS RECONSTRUCTION USING ENDOPROSTHESIS AND LOWER DEEPITHELIALIZED FLAP IN PROPHYLACTIC MASTECTOMY
SIMULTANEOUS RECONSTRUCTION USING ENDOPROSTHESIS AND LOWER DEEPITHELIALIZED FLAP IN PROPHYLACTIC MASTECTOMY

To cite this article:

Zikiryakhodzhaev AD, Manturova NE, Mistakopylo FN, Sukhotko AS, Kovantsev SD, Duadze IS. Simultaneous reconstruction using endoprosthesis and lower deepithelialized flap in prophylactic mastectomy. Plastic Surgery and Aesthetic Medicine. 2025;(2‑2):16‑24. (In Russ., In Engl.)
https://doi.org/10.17116/plast.hirurgia202502216

Подписка 2026 Пластическая хирургия и эстетическая медицина (Plastic Surgery and Aesthetic Medicine)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

OBJECTIVE

To analyze long-term outcomes and quality of life after simultaneous breast reconstruction.

MATERIAL AND METHODS

The study included 31 patients who underwent prophylactic subcutaneous mastectomy and simultaneous reconstruction with implant and inferior de-epithelialized dermal flap.

RESULTS

Complications occurred in 19.35% of cases. Implant volume and de-epidermized skin were not related to the incidence of complications. Postoperative satisfaction with mammary gland and psychosocial well-being were significantly lower (p<0.001), but no significant difference in sexual and physical well-being was found (p=0.118 and 0.084, respectively).

CONCLUSION

The authors presented a method of breast reconstruction after subcutaneous prophylactic mastectomy. De-epithelialized dermal flap as additional reinforcement of the lower pole of the reconstructed mammary gland is advisable to achieve the best aesthetic results in patients with severe ptosis (grade III-IV) and minimal pinch test.

Keywords:

subcutaneous mastectomy
BREAST-Q
ptosis
implant

Authors:

Zikiryakhodzhaev A.D.

Hertsen Moscow Oncology Research Center;
Peoples’s Friendship University of Russia;
Sechenov First Moscow State Medical University

Manturova N.E.

Pirogov Russian National Research Medical University;
Institute of Plastic Surgery and Cosmetology

Mistakopylo F.N.

Frau Clinic 1

Sukhotko A.S.

Treatment and Rehabilitation Centre

Kovantsev S.D.

Treatment and Rehabilitation Centre

Duadze I.S.

Hertsen Moscow Oncology Research Center

Received:

14.04.2025

Accepted:

11.05.2025

Close metadata

References:

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  2. de Vita R, Buccheri EM, Villanucci A, Pozzi M. Breast Reconstruction Actualized in Nipple-sparing Mastectomy and Direct-to-implant, Prepectoral Polyurethane Positioning: Early Experience and Preliminary Results. Clinical Breast Cancer. 2019;19(2):e358-e363. https://doi.org/10.1016/j.clbc.2018.12.015
  3. Heimes AS, Stewen K, Hasenburg A. Psychosocial Aspects of Immediate versus Delayed Breast Reconstruction. Breast Care. 2017;12(6):374-377.  https://doi.org/10.1159/000485234
  4. Zarei M, Carlson GW. Periareolar Skin-Sparing Mastectomy and Immediate Implant-Based Reconstruction: A Reappraisal. Annals of Plastic Surgery. 2024;92(6S Suppl 4):S441-S444. https://doi.org/10.1097/SAP.0000000000003946
  5. De Vita R, Pozzi M, Zoccali G, Costantini M, Gullo P, Buccheri EM, Varanese A. Skin-reducing mastectomy and immediate breast reconstruction in patients with macromastia. Clinical Cancer Research. 2015;34:120.  https://doi.org/10.1186/s13046-015-0227-5
  6. Moo TA, Nelson JA, Sevilimedu V, Charyn J, Le TV, Allen RJ, Mehrara BJ, Barrio AV, Capko DM, Pilewskie M, Heerdt AS, Tadros AB, Gemignani ML, Morrow M, Sacchini V. Strategies to avoid mastectomy skin-flap necrosis during nipple-sparing mastectomy. British Journal of Surgery. 2023; 110(7):831-838.  https://doi.org/10.1093/bjs/znad107
  7. Colizzi L, Agostini T, Pascone C, Gandini D, Pantaloni M, Lazzeri D. A dermomuscular pocket provides superior coverage of the implant in skin-reducing mastectomies. Aesthetic Plastic Surgery. 2010;34(5):675-677.  https://doi.org/10.1007/s00266-010-9508-8
  8. Bostwick J 3rd. Breast reconstruction after mastectomy. Seminars in Surgical Oncology. 1988;4(4):274-279.  https://doi.org/10.1002/ssu.2980040413
  9. Ticha P, Sukop A. Patient-reported outcomes in bilateral prophylactic mastectomy with breast reconstruction: A narrative review. Breast. 2024;73: 103602. https://doi.org/10.1016/j.breast.2023.103602
  10. Murphy AI, Asadourian PA, Mellia JA, Rohde CH. Complications Associated with Contralateral Prophylactic Mastectomy: A Systematic Review and Meta-Analysis. Plastic and Reconstructive Surgery. 2022;150:61S-72S.  https://doi.org/10.1097/PRS.0000000000009493
  11. Peoples AE, Waler AR, Duet ML, Prabhu SS, Katz AJ. Comparing Outcomes in the Therapeutic and Prophylactic Breast for Bilateral Mastectomy with Implant-Based Breast Reconstruction. Annals of Plastic Surgery. 2023; 90(6S Suppl 4):S375-S378. https://doi.org/10.1097/SAP.0000000000003460
  12. Seth I, Seth N, Bulloch G, Rozen WM, Hunter-Smith DJ. Systematic Review of Breast-Q: A Tool to Evaluate Post-Mastectomy Breast Reconstruction. Breast Cancer. 2021;13:711-724.  https://doi.org/10.2147/BCTT.S256393
  13. Clarijs ME, Peeters NJMCV, van Dongen SAF, Koppert LB, Pusic AL, Mureau MAM, Rijken BFM. Quality of Life and Complications after Nipple-versus Skin-Sparing Mastectomy followed by Immediate Breast Reconstruction: A Systematic Review and Meta-Analysis. Plastic and Reconstructive Surgery. 2023;152(1):12e-24e.  https://doi.org/10.1097/PRS.0000000000010155
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