Фето-фетальный трансфузионный синдром. Синдром анемии-полицитемии. Методы диагностики. Варианты лечения

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Рекомендуем статьи по данной теме:

Осложнения фетоскопической лазерной коагуляции сосудистых анастомозов плаценты при фето-фетальном трансфузионном синдроме. Проблемы репродукции. 2024;(5):55-63

Проведен обзор литературы с анализом результатов исследований по оценке эффективности диагностики и лечения при фето-фетальном трансфузионном синдроме (ФФТС) и синдроме анемии-полицитемии (САП) за последние 15 лет в базах данных PubMed, Scopus и E-library. В статье приведены современные представления о патогенезе САП и ФФТС, объяснены различия между ними, описаны методы диагностики и актуальные способы лечения при этих осложнениях беременности. Обоснована важность своевременного выявления и начала лечения больных с САП и ФФТС.

Ключевые слова:

осложнения многоплодной монохориальной беременности

фето-фетальный трансфузионный синдром

синдром анемии-полицитемии

фетоскопическая лазерная коагуляция анастомозов

Авторы:

Кузнецов П.А.

ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России

ORCID: 0000-0003-2492-3910

Порываев А.А.

ORCID: 0009-0001-2395-5999

Дата поступления:

05.02.2024

Дата принятия в печать:

13.02.2024

Список литературы:

Клинические рекомендации МЗ РФ «Многоплодная беременность», 2021. https://cr.minzdrav.gov.ru/recomend/638_1
Ramesha Papanna MD, MPH, Eric Bergh, MD Twin-twin transfusion syndrome: Screening, prevalence, pathophysiology, and diagnosis. 2023. https://www.uptodate.com/contents/twin-twin-transfusion-syndrome-screening-prevalence-pathophysiology-and-diagnosis?search=Twin-twin%20transfusion%20syndrome:%20Screening,%20prevalence,pathophysiology,%20and%20diagnosis&source=search_result&selectedTitle=1~38&usage_type=default&display_rank=1
Lopriore E, Deprest J, Slaghekke F, Oepkes D, Middeldorp JM, Vandenbussche FP, Lewi L. Placental characteristics in monochorionic twins with and without twin anemia-polycythemia sequence. Obstet Gynecol. 2008;112:4:753-758. https://doi.org/10.1097/AOG.0b013e318187e1ff
Sebire NJ, Snijders RJ, Hughes K, Sepulveda W, Nicolaides KH. The hidden mortality of monochorionic twin pregnancies. Br J Obstet Gynaecol. 1997;104:10:1203-1207. https://doi.org/10.1111/j.1471-0528.1997.tb10948.x
Denbow ML, Cox P, Taylor M, Hammal DM, Fisk NM. Placental angioarchitecture in monochorionic twin pregnancies: relationship to fetal growth, fetofetal transfusion syndrome, and pregnancy outcome. Am J Obstet Gynecol. 2000;182:2:417-426. https://doi.org/10.1016/s0002-9378(00)70233-x
Bajoria R, Ward S, Sooranna SR. Influence of vasopressin in the pathogenesis of oligohydramnios-polyhydramnios in monochorionic twins. Eur J Obstet Gynecol Reprod Biol. 2004;113:1:49-55. https://doi.org/10.1016/S0301-2115(03)00318-X
Barrea C, Alkazaleh F, Ryan G, McCrindle BW, Roberts A, Bigras JL, Barrett J, Seaward GP, Smallhorn JF, Hornberger LK. Prenatal cardiovascular manifestations in the twin-to-twin transfusion syndrome recipients and the impact of therapeutic amnioreduction. Am J Obstet Gynecol. 2005;192:3:892-902. https://doi.org/10.1016/j.ajog.2004.09.015
Donepudi R, Mann LK, Wohlmuth C, Johnson A, Bebbington MW, Moise KJ Jr, Boudreaux DS, Gardiner H, Papanna R. Recipient umbilical artery elongation (redundancy) in twin-twin transfusion syndrome. Am J Obstet Gynecol. 2017;217:2:206.e1-206.e11. https://doi.org/10.1016/j.ajog.2017.04.024
Bajoria R, Ward S, Chatterjee R. Natriuretic peptides in the pathogenesis of cardiac dysfunction in the recipient fetus of twin-twin transfusion syndrome. Am J Obstet Gynecol. 2002;186:1:121-127. https://doi.org/10.1067/mob.2002.118845
Bajoria R, Sullivan M, Fisk NM. Endothelin concentrations in monochorionic twins with severe twin-twin transfusion syndrome. Hum Reprod. 1999;14:6:1614-1618. https://doi.org/10.1093/humrep/14.6.1614
van den Wijngaard JP, Umur A, Krediet RT, Ross MG, van Gemert MJ. Modeling a hydropic recipient twin in twin-twin transfusion syndrome. Am J Physiol Regul Integr Comp Physiol. 2005;288:4:R799-814. https://doi.org/10.1152/ajpregu.00635.2004
Quintero RA, Morales WJ, Allen MH, Bornick PW, Johnson PK, Kruger M. Staging of twin-twin transfusion syndrome. J Perinatol. 1999;19:8 Pt 1:550-555. https://doi.org/10.1038/sj.jp.7200292
Stirnemann J, Slaghekke F, Khalek N, Winer N, Johnson A, Lewi L, Massoud M, Bussieres L, Aegerter P, Hecher K, Senat MV, Ville Y. Intrauterine fetoscopic laser surgery versus expectant management in stage 1 twin-to-twin transfusion syndrome: an international randomized trial. Am J Obstet Gynecol. 2021;224:5:528.e1-528.e12. https://doi.org/10.1016/j.ajog.2020.11.031
Di Mascio D, Khalil A, D’Amico A, Buca D, Benedetti Panici P, Flacco ME, Manzoli L, Liberati M, Nappi L, Berghella V, D’Antonio F. Outcome of twin-twin transfusion syndrome according to Quintero stage of disease: systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2020;56:6:811-820. https://doi.org/10.1002/uog.22054
Nassr AA, Hessami K, Zargarzadeh N, Krispin E, Mostafaei S, Habli MA, Papanna R, Emery SP, Shamshirsaz AA. Fetoscopic laser photocoagulation versus expectant management for stage I twin-to-twin transfusion syndrome: A systematic review and meta-analysis. Prenat Diagn. 2023;43:9:1229-1238. https://doi.org/10.1002/pd.6413
Wilson RD, Johnson A, Ryan G. Current controversies in prenatal diagnosis 2: Should laser ablation of placental anastomoses be used in all cases of twin to twin transfusion? Prenat Diagn. 2009;29:1:6-10. https://doi.org/10.1002/pd.2162
Wagner MM, Lopriore E, Klumper FJ, Oepkes D, Vandenbussche FP, Middeldorp JM. Short- and long-term outcome in stage 1 twin-to-twin transfusion syndrome treated with laser surgery compared with conservative management. Am J Obstet Gynecol. 2009;201:3:286.e1-6. https://doi.org/10.1016/j.ajog.2009.05.034
Molina S, Papanna R, Moise KJ Jr, Johnson A. Management of stage I twin-to-twin transfusion syndrome: an international survey. Ultrasound Obstet Gynecol. 2010;36:1:42-47. https://doi.org/10.1002/uog.7566
Bower SJ, Flack NJ, Sepulveda W, Talbert DG, Fisk NM. Uterine artery blood flow response to correction of amniotic fluid volume. Am J Obstet Gynecol. 1995;173:2:502-507. https://doi.org/10.1016/0002-9378(95)90273-2
Leung WC, Jouannic JM, Hyett J, Rodeck C, Jauniaux E. Procedure-related complications of rapid amniodrainage in the treatment of polyhydramnios. Ultrasound Obstet Gynecol. 2004;23:2:154-158. https://doi.org/10.1002/uog.972
Chmait RH, Kontopoulos EV, Korst LM, Llanes A, Petisco I, Quintero RA. Stage-based outcomes of 682 consecutive cases of twin-twin transfusion syndrome treated with laser surgery: the USFetus experience. Am J Obstet Gynecol. 2011;204:5:393.e1-6. https://doi.org/10.1016/j.ajog.2011.02.001
Crombleholme TM, Shera D, Lee H, Johnson M, D’Alton M, Porter F, Chyu J, Silver R, Abuhamad A, Saade G, Shields L, Kauffman D, Stone J, Albanese CT, Bahado-Singh R, Ball RH, Bilaniuk L, Coleman B, Farmer D, Feldstein V, Harrison MR, Hedrick H, Livingston J, Lorenz RP, Miller DA, Norton ME, Polzin WJ, Robinson JN, Rychik J, Sandberg PL, Seri I, Simon E, Simpson LL, Yedigarova L, Wilson RD, Young B. A prospective, randomized, multicenter trial of amnioreduction vs selective fetoscopic laser photocoagulation for the treatment of severe twin-twin transfusion syndrome. Am J Obstet Gynecol. 2007;197:4:396.e1-9. https://doi.org/10.1016/j.ajog.2007.07.020
Roberts D, Neilson JP, Kilby MD, Gates S. Interventions for the treatment of twin-twin transfusion syndrome. Cochrane Database Syst Rev. 2014;2014:1:CD002073. https://doi.org/10.1002/14651858.CD002073.pub3
Yinon Y, Ashwal E, Weisz B, Chayen B, Schiff E, Lipitz S. Selective reduction in complicated monochorionic twins: prediction of obstetric outcome and comparison of techniques. Ultrasound Obstet Gynecol. 2015;46:6:670-677. https://doi.org/10.1002/uog.14879
van Klink JMM, Slaghekke F, Balestriero MA, Scelsa B, Introvini P, Rustico M, Faiola S, Rijken M, Koopman HM, Middeldorp JM, Oepkes D, Lopriore E. Neurodevelopmental outcome at 2 years in twin-twin transfusion syndrome survivors randomized for the Solomon trial. Am J Obstet Gynecol. 2016;214:Issue 1:113.e1-113.e7. https://doi.org/10.1016/j.ajog.2015.08.033
Kanazawa S, Ozawa K, Muromoto J, Sugibayashi R, Wada Y, Wada, S, Ito Y, Sago H. Risk profiling of the Solomon technique versus selective technique of fetoscopic laser surgery for twin—twin transfusion syndrome. Twin Res Hum Genet. 2021;24:1:42-48. https://doi.org/10.1017/thg.2020.94
Knijnenburg PJC, Lopriore E, Ge Y, Scholl IM, van Klink JMM, Haak MC, Middeldorp JM, Klumper FJCM, Oepkes D, Sun L, Slaghekke F. Placental abruption after fetoscopic laser surgery in twin-twin transfusion syndrome: The Role of the Solomon technique. Fetal Diagn Ther. 2021;48:9:660-666. https://doi.org/10.1159/000517800
Bamberg C, Hecher K. Twin-to-twin transfusion syndrome: Controversies in the diagnosis and management. Best Pract Res Clin Obstet Gynaecol. 2022;84:143-154. https://www.sciencedirect.com/science/article/abs/pii/S1521693422000529
Society for Maternal-Fetal Medicine; Simpson LL. Twin-twin transfusion syndrome. Am J Obstet Gynecol. 2013;208:1:3-18. https://doi.org/10.1016/j.ajog.2012.10.880
Shek NW, Hillman SC, Kilby MD. Single-twin demise: pregnancy outcome. Best Pract Res Clin Obstet Gynaecol. 2014;28:2:249-263. https://doi.org/10.1016/j.bpobgyn.2013.11.003
Quarello E, Stirnemann J, Nassar M, Nasr B, Bernard JP, Leleu-Huard F, Ville Y. Outcome of anaemic monochorionic single survivors following early intrauterine rescue transfusion in cases of feto-fetal transfusion syndrome. BJOG. 2008;115:5:595-601. https://doi.org/10.1111/j.1471-0528.2007.01659.x
Lopriore E, Middeldorp JM, Oepkes D, Kanhai HH, Walther FJ, Vandenbussche FP. Twin anemia-polycythemia sequence in two monochorionic twin pairs without oligo-polyhydramnios sequence. Placenta. 2007;28:1:47-51. https://doi.org/10.1016/j.placenta.2006.01.010
Lewi L, Jani J, Blickstein I, Huber A, Gucciardo L, Van Mieghem T, Doné E, Boes AS, Hecher K, Gratacós E, Lewi P, Deprest J. The outcome of monochorionic diamniotic twin gestations in the era of invasive fetal therapy: a prospective cohort study. Am J Obstet Gynecol. 2008;199:5:514.e1-8. https://doi.org/10.1016/j.ajog.2008.03.050
Robyr R, Lewi L, Salomon LJ, Yamamoto M, Bernard JP, Deprest J, Ville Y. Prevalence and management of late fetal complications following successful selective laser coagulation of chorionic plate anastomoses in twin-to-twin transfusion syndrome. Am J Obstet Gynecol. 2006;194:3:796-803. https://doi.org/10.1016/j.ajog.2005.08.069
Slaghekke F, Kist WJ, Oepkes D, Pasman SA, Middeldorp JM, Klumper FJ, Walther FJ, Vandenbussche FP, Lopriore E. Twin anemia-polycythemia sequence: diagnostic criteria, classification, perinatal management and outcome. Fetal Diagn Ther. 2010;27:4:181-190. https://doi.org/10.1159/000304512
Костюков К.В., Гладкова К.А. Диагностика фето-фетального трансфузионного синдрома, синдрома анемии-полицитемии при монохориальной многоплодной беременности. Акушерство и гинекология. 2016;1:10-15. https://doi.org/10.18565/aig.2016.1.10-15
Tollenaar LSA, Slaghekke F, Lewi L, Ville Y, Lanna M, Weingertner A, Ryan G, Arévalo S, Khalil A, Brock CO, Klaritsch P, Hecher K, Gardener G, Bevilacqua E, Kostyukov KV, Bahtiyar MO, Kilby MD, Tiblad E, Oepkes D, Lopriore E; Collaborators. Treatment and outcome of 370 cases with spontaneous or post-laser twin anemia-polycythemia sequence managed in 17 fetal therapy centers. Ultrasound Obstet Gynecol. 2020;56:3:378-387. https://doi.org/10.1002/uog.22042
Slaghekke F, van Klink JM, Koopman HM, Middeldorp JM, Oepkes D, Lopriore E. Neurodevelopmental outcome in twin anemia-polycythemia sequence after laser surgery for twin-twin transfusion syndrome. Ultrasound Obstet Gynecol. 2014;44:3:316-321. https://doi.org/10.1002/uog.13387
Men-Jean Lee, MD, Debra Guinn, MD, FACOG. Antenatal corticosteroid therapy for reduction of neonatal respiratory morbidity and mortality from preterm delivery. 2023. https://www.uptodate.com/contents/antenatal-corticosteroid-therapy-for-reduction-of-neonatal-respiratory-morbidity-and-mortality-from-preterm-delivery?topicRef=130852&source=see_link
Tollenaar LSA, Slaghekke F, Lewi L, Colmant C, Lanna M, Weingertner AS, Ryan G, Arévalo S, Klaritsch P, Tavares de Sousa M, Khalil A, Papanna R, Gardener GJ, Bevilacqua E, Kostyukov KV, Bahtiyar MO, Kilby MD, Tiblad E, Oepkes D, Lopriore E. Spontaneous twin anemia polycythemia sequence: diagnosis, management, and outcome in an international cohort of 249 cases. Am J Obstet Gynecol. 2021;224:2:213.e1-213.e11. https://doi.org/10.1016/j.ajog.2020.07.041
Breathnach FM, McAuliffe FM, Geary M, Daly S, Higgins JR, Dornan J, Morrison JJ, Burke G, Higgins S, Dicker P, Manning F, Carroll S, Malone FD; Perinatal Ireland Research Consortium. Optimum timing for planned delivery of uncomplicated monochorionic and dichorionic twin pregnancies. Obstet Gynecol. 2012;119:1:50-59. https://doi.org/10.1097/AOG.0b013e31823d7b06
Kenneth J Moise Jr, MD. Intrauterine fetal transfusion of red cells. 2023. https://www.uptodate.com/contents/intrauterine-fetal-transfusion-of-red-cells?topicRef=130852&source=see_link
Habli M, Bombrys A, Lewis D, Lim FY, Polzin W, Maxwell R, Crombleholme T. Incidence of complications in twin-twin transfusion syndrome after selective fetoscopic laser photocoagulation: a single-center experience. Am J Obstet Gynecol. 2009;201:4:417.e1-7. https://doi.org/10.1016/j.ajog.2009.07.046
Tollenaar LSA, Lopriore E, Slaghekke F, Oepkes D, Middeldorp JM, Haak MC, Klumper FJCM, Tan RNGB, Rijken M, Van Klink JMM. High risk of long-term neurodevelopmental impairment in donor twins with spontaneous twin anemia-polycythemia sequence. Ultrasound Obstet Gynecol. 2020;55:1:39-46. https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.20846

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