Personificated approach to management tactics for patients with atrophic vulvovaginitis in postmenopause

Pestrikova T.Iu.

Kafedra akusherstva i ginekologii Dal'nevostochnogo gosudarstvennogo meditsinskogo universiteta, Khabarovsk

Iurasova E.A.

Kafedra akusherstva i ginekologii Dal'nevostochnogo gosudarstvennogo meditsinskogo universiteta, Khabarovsk

Shveeva M.A.

Far Eastern State Medical University of the Russian Ministry of Health, Khabarovsk, Russia

Kovaleva T.D.

Kafedra akusherstva i ginekologii Dal'nevostochnogo gosudarstvennogo meditsinskogo universiteta, Khabarovsk

Personificated approach to management tactics for patients with atrophic vulvovaginitis in postmenopause

Authors:

Pestrikova T.Iu., Iurasova E.A., Shveeva M.A., Kovaleva T.D.

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Journal: Russian Bulletin of Obstetrician-Gynecologist. 2020;20(3): 62‑67

DOI: 10.17116/rosakush20202003162

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To cite this article:

Pestrikova TIu, Iurasova EA, Shveeva MA, Kovaleva TD. Personificated approach to management tactics for patients with atrophic vulvovaginitis in postmenopause. Russian Bulletin of Obstetrician-Gynecologist. 2020;20(3):62‑67. (In Russ.)
https://doi.org/10.17116/rosakush20202003162

Подписка 2025-2 (Russian Bulletin of Obstetrician-Gynecologist)

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Introduction. One of the pressing problems in gynecology, which dramatically reduces the quality of life in women in menopause, is the syndrome of vulvovaginal atrophy due to a deficit of estrogen, which occurs in 40—57% of women in postmenopause. Aim. Evaluate the effectiveness of a non-hormonal preparation containing polyglucuronic acid in treating patients with atrophic vulvovaginitis in postmenopause. Material and methods. The examination included 34 patients diagnosed with atrophic vulvovaginitis in postmenopause. To verify the diagnosis, in addition to the results of clinical examination (general and gynecological), patients were carried out laboratory tests (microscopic and molecular-biological examination by polymerase chain reaction in real time, determination of vaginal pH). Results. Local therapy with the preparation containing polyglucuronic acid in patients with atrophic vulvovaginitis in postmenopause allowed restoring vaginal biotope and eliminating symptoms of this nosological form with statistically significant efficiency. Conclusion. It has been established that the first line of therapy for patients with atrophic vaginitis in the postmenopause is preparations promoting long-term vaginal moisturizing. First of all, they include vaginal forms containing polyglucuronic acid.

Keywords:

atrophic vulvovaginitis

postmenopause

vaginal biotope

vaginal forms containing polyglucuronic acid

Authors:

Pestrikova T.Iu.

Kafedra akusherstva i ginekologii Dal'nevostochnogo gosudarstvennogo meditsinskogo universiteta, Khabarovsk

Iurasova E.A.

Kafedra akusherstva i ginekologii Dal'nevostochnogo gosudarstvennogo meditsinskogo universiteta, Khabarovsk

Shveeva M.A.

Far Eastern State Medical University of the Russian Ministry of Health, Khabarovsk, Russia

Kovaleva T.D.

Kafedra akusherstva i ginekologii Dal'nevostochnogo gosudarstvennogo meditsinskogo universiteta, Khabarovsk

List of references:

Sinha A, Ewies AAA. Non-hormonal topical treatment of vul-vovaginal atrophy: an up-to-date overview. . 2013;16:305-312.
Griebling TL, Liao Z, Smith PG. Systemic and topical hormone therapies reduce vaginal innervation density in postmenopausal women. . 2012;19:630-635.
Ermakova EI, Balan VE, Tikhomirova EV, Lazareva IN, Lapina AV, Panin EM. Genitourinar menopausal syndrome: diagnosis and treatment principles (brief clinical recommendations). . 2017;17:6:89-95. (In Russ.).
Yureneva SV, Glazunova AV, Eprikyan EG, Donnikov AE, Ezhova LS. Clinical and pathogenetic aspects of the treatment of vulvovaginal atrophy in postmenopausal women. . 2017;6:143-150. (In Russ.).
Eprikyan EG, Yureneva SV, Ermakova EI, Glazunova AV. Genitourinar menopausal syndrome: optimization of the treatment of vaginal symptoms. . 2018;20:3:52-56. (In Russ.).
Eprikyan EG, Yureneva SV, Donnikov AE, Ezhova LS. The relationship between the symptoms of vulvovaginal epithelial atrophy and vaginal microbiota in postmenopausal women. . 2019;11:152-159. (In Russ.).
Rebecca M. Brotman, Michelle D. Shardell, Pawel Gajer, Doug Fadrosh, Kathryn Chang, Michelle I. Silver, Raphael P. Viscidi, Anne E. Burke, Jacques Ravel, and Patti E. Gravitt. Association between the vaginal microbiota, menopause status, and signs of vulvovaginal atrophy. . 2014;21:5:120-123.
Kingsberg SA, Krychmanm ML. Resistance and barriers to local estrogen therapy in women with atrophic vaginitis. . 2013;1567-1574.
James H. Pickar. Emerging therapies for postmenopausal vaginal atrophy. . 2013;75:3-6.
Instructions for use of the drug Multi-Gin LiquiGel. (In Russ.).
North American Menopause Society (2007). The role of local vaginal estrogen for treatment of vaginal atrophy in postmenopausal women: 2007 position statement of the North American Menopause Society. 14:355-369.
Pestrikova TYu, Yurasova EA, Yachinskaya TV, Kovaleva TD. Menopausal hormone therapy or non-hormonal treatment: a rational choice. . 2015;17:3:34-39. (In Russ.).
Rogovskaya SI, Radzinskii VE, Balan VE, Mashovets SP, Moskvina NB, Akimkin VG, Artymuk NV, Bakhalova TE, Bebneva TN, Belokrinitskaya TE, Volkov VG, Gaidarova AKh, Dolgushina VF, Evtushenko ID, Korolenkova LI, Krapivina MS, Kukarekaya II, Lebedenko EYu, Ledin EV, Ledina AV, Lipova EV, Mingaleva NV, Manzhosova MI, Molchanova IV, Pestrikova TYu, Podzolkova NM, Sandakova EA, Tkachenko LV, Fatkullin IF, Shaderkina VI. Malignancy and oncophobia in women of Balzac age. Project Oncopatrol. . 2017;4:37:334:25-31. (In Russ.).
Tersigni C, Di Simone N, Tempestilli E, Cianfrini F, Russo R, Moruzzi MC, Amar ID, Fiorelli A, Scambia G, Villa P. Non-hormonal treatment of vulvo-vaginal atrophy-related symptoms in post-menopausal women. . 2015;35:8:835-838.

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