Objective — to reveal the clinical features of pregnancy in non-diabetic women having a big fetus. Subject and methods. A total of 3760 single fetus deliveries that had ended in a live birth at term in 2006—2012 were analyzed. All the puerperas included in the study were divided according to their neonates’ weight into 2 groups: 1) 3384 women who had given birth to babies weighing, on the average, 3000 to 3999 g; 2) 376 women whose babies’ weight was 4000 g or more. The patients were examined using standard clinical, laboratory, and instrumental methods, including those excluding gestational diabetes mellitus. A statistical analysis of the results used Student t-test and Z-test. Results. The rate of vaginal delivery of average and big fetuses was 79.8 and 68.1%, respectively (p<0.05). That of cesarean deliveries of a big fetus was virtually twice greater than that in the group of mothers who had given birth to infants with an average weight. Abnormal delivery, a clinically contracted pelvis, and labor induction due to a tendency to postterm pregnancy in a patient having a big fetus substantially increased the risk of cesarean section and operative vaginal delivery. In case of a big fetus, the labor was established to be significantly longer mainly due to prolongation of its second stage in a group of primigravidas. Shoulder dystocia was more common in the group of patients with a big fetus. Conclusion. Labor induction and uterine inertia in non-diabetic women having a big fetus are risk factors for cesarean section and operative vaginal delivery. Due to the fact that prenatal diagnosis of a big fetus is inadequately accurate, the expectant management of labor and the timely diagnosis of intranatal complications are optimal in non-diabetic parturients having a big fetus. The authors declare no conflicts of interest.