Cytogenetic disorders in embryos during non-developing pregnancy

Bashmakova N.V.; Tret'iakova T.B.; Demchenko N.S.

doi:https://doi.org/

Bashmakova N.V.

Ural Scientific Research Institute of Maternity and Child Health Ministry of the Russia, Yekaterinburg, Russia

Tret'iakova T.B.

NII okhrany materinstva i mladenchestva, Ekaterinburg

Demchenko N.S.

NII okhrany materinstva i mladenchestva, Ekaterinburg

Cytogenetic disorders in embryos during non-developing pregnancy

Authors:

Bashmakova N.V., Tret'iakova T.B., Demchenko N.S.

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Journal: Russian Bulletin of Obstetrician-Gynecologist. 2013;13(4): 18‑21

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To cite this article:

Bashmakova NV, Tret'iakova TB, Demchenko NS. Cytogenetic disorders in embryos during non-developing pregnancy. Russian Bulletin of Obstetrician-Gynecologist. 2013;13(4):18‑21. (In Russ.)

Подписка 2026 Российский вестник акушера-гинеколога (Russian Bulletin of Obstetrician-Gynecologist)

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Abstract:

Seventy-one embryonic tissues from women with first-trimester non-developing pregnancy were examined to study the rate and pattern of chromosomal abnormalities. Chorionic villi obtained from abortion specimens were cytogenetically analyzed to determine the karyotype of a fetus. The analysis revealed all types of chromosomal disorders: trisomy, monosomy, triploidy, and mosaic karyotypes. Trisomy was the most common abnormal abortus karyotype (71%). Trisomy 21 and trisomy 160 were most frequently encountered. The interesting feature of the findings is the high rate of mosaic chromosomal disorders accounting for 34% of abnormal karyotypes.

Keywords:

non-developing pregnancy

fetal karyotype

mosaicism

anembryony

Authors:

Bashmakova N.V.

Ural Scientific Research Institute of Maternity and Child Health Ministry of the Russia, Yekaterinburg, Russia

Tret'iakova T.B.

NII okhrany materinstva i mladenchestva, Ekaterinburg

Demchenko N.S.

NII okhrany materinstva i mladenchestva, Ekaterinburg

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