The efficiency of treatment in patients with inflammatory small pelvic diseases complicated by pelviperitonitis, by applying video-assisted laparoscopy (VAL) in the early periods of treatment in combination with traditional therapy (n=29) and traditional therapy only (n=39), was analyzed examining the time courses of changes in endogenous intoxication parameters. The use of VAL in the combination therapy of patients with pelviperitonitis made it possible to specify the diagnosis, site, and extent of the inflammatory process and to carry out abdominal sanitization and drainage and resulted in the rapider disappearance of peritoneal symptoms, regression of pain syndrome, reductions in endogenous intoxication and pelviperitonitis treatment duration.