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Malyavin A.G.

A.I. Evdokimov Moscow State University of Medicine and Dentistry

Gorelov A.V.

A.I. Yevdokimov Moscow State University of Medicine and Dentistry of the Ministry of the Healthcare of the Russian Federation;
Central Research Institute of Epidemiology of Rospotrebnadzor

Vasenina E.E.

Russian Medical Academy of Continuing Professional Education

Ekusheva E.V.

Federal Scientific and Clinical Center of Specialized Types of Medical Care and Medical Technologies of the Federal Medical and Biological Agency of Russia

Kobzeva N.D.

Rostov State Medical University of the Ministry of Health of Russia

Kovalchuk V.V.

Semashko City Hospital No. 38

Esaulenko E.V.

Saint Petersburg State Pediatric Medical University of the Ministry of Health of Russia

Postinfectious asthenia: modern approaches to therapy. The Russian Scientific Medical Society of Therapists and the National Association of Infectious Diseases Specialists named after academician of the RAS Pokrovsky V.I. Expert Council Resolution

Authors:

Malyavin A.G., Gorelov A.V., Vasenina E.E., Ekusheva E.V., Kobzeva N.D., Kovalchuk V.V., Esaulenko E.V.

More about the authors

Journal: Russian Journal of Preventive Medicine. 2023;26(9): 88‑97

DOI: 10.17116/profmed20232609188

Read: 14221 times

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POSTINFECTIOUS ASTHENIA: MODERN APPROACHES TO THERAPY. THE RUSSIAN SCIENTIFIC MEDICAL SOCIETY OF THERAPISTS AND THE NATIONAL ASSOCIATION OF INFECTIOUS DISEASES SPECIALISTS NAMED AFTER ACADEMICIAN OF THE RAS POKROVSKY V.I. EXPERT COUNCIL RESOLUTION
POSTINFECTIOUS ASTHENIA: MODERN APPROACHES TO THERAPY. THE RUSSIAN SCIENTIFIC MEDICAL SOCIETY OF THERAPISTS AND THE NATIONAL ASSOCIATION OF INFECTIOUS DISEASES SPECIALISTS NAMED AFTER ACADEMICIAN OF THE RAS POKROVSKY V.I. EXPERT COUNCIL RESOLUTION

To cite this article:

Malyavin AG, Gorelov AV, Vasenina EE, Ekusheva EV, Kobzeva ND, Kovalchuk VV, Esaulenko EV. Postinfectious asthenia: modern approaches to therapy. The Russian Scientific Medical Society of Therapists and the National Association of Infectious Diseases Specialists named after academician of the RAS Pokrovsky V.I. Expert Council Resolution. Russian Journal of Preventive Medicine. 2023;26(9):88‑97. (In Russ.)
https://doi.org/10.17116/profmed20232609188

Подписка 2026 Профилактическая медицина (Russian Journal of Preventive Medicine)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Postinfectious asthenia: modern approaches to therapy. The Russian Scientific Medical Society of Therapists and the National Association of Infectious Diseases Specialists named after academician of the RAS Pokrovsky V.I. Expert Council Resolution

Authors:

Malyavin A.G.

A.I. Evdokimov Moscow State University of Medicine and Dentistry

Gorelov A.V.

A.I. Yevdokimov Moscow State University of Medicine and Dentistry of the Ministry of the Healthcare of the Russian Federation;
Central Research Institute of Epidemiology of Rospotrebnadzor

Vasenina E.E.

Russian Medical Academy of Continuing Professional Education

Ekusheva E.V.

Federal Scientific and Clinical Center of Specialized Types of Medical Care and Medical Technologies of the Federal Medical and Biological Agency of Russia

Kobzeva N.D.

Rostov State Medical University of the Ministry of Health of Russia

Kovalchuk V.V.

Semashko City Hospital No. 38

Esaulenko E.V.

Saint Petersburg State Pediatric Medical University of the Ministry of Health of Russia

Received:

10.08.2023

Accepted:

11.08.2023

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References:

  1. Lopez-Leon S, Wegman-Ostrosky T, Perelman C, Sepulveda R, Rebolledo PA, Cuapio A, Villapol S. More than 50 long-term effects of COVID-19: a systematic review and meta-analysis. Scientific Reports. 2021;11(1):16144. https://doi.org/10.1038/s41598-021-95565-8
  2. Burchinsky SG. Asthenic syndrome and cerebrovascular pathology: possibilities of pathogenetic pharmacotherapy. Mezhdunarodnyj nevrologicheskij zhurnal. 2014;7(69):69-74.(In Russ.).
  3. Klok FA, Boon GJAM, Barco S, Endres M, Geelhoed JJM, Knauss S, Rezek SA, Spruit MA, Vehreschild J, Siegerink B. The Post-COVID-19 Functional Status scale: a tool to measure functional status over time after COVID-19. The EuropeanRespiratory Journal. 2020;56(1):2001494. https://doi.org/10.1183/13993003.01494-2020
  4. Methodological recommendations «Features of Long-COVID infection clinical course. Therapeutic and rehabilitation measures». Terapija. 2022; 1(suppl):1-147.  https://doi.org/10.18565/therapy.2022.1suppl.1-147
  5. Polunina AG, Osinovskaia NA, Gudkova AN, Guekht AB. Influence of cytoflavin on symptoms of asthenia, emotional disorders and autonomic regulation in patients with organic asthenic disorder. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova.2014;114(2):28-33. (In Russ.).
  6. Shabanov PD, Mokrenko EV. Synthetic inducers of interferon in the treatment and prevention of acute inflammatory diseases of the upper respiratory tract. Poliklinika. 2015;3:117-120 (In Russ.).
  7. Isakov VA, Kovalenko AL, Martynova OV, Turkin VV, Makarov VI. Efficacy of Cytoflavin in Therapy of Encephalophathy in Patients with Neuroinfection. Antibiotiki i himioterapija. 2010;55(1-2):36-41. (In Russ.).
  8. Ekusheva EV, Voitenkov VB, Rizakhanova OA. The effectiveness of cytoflavin in complex therapy of patients with the coronavirus infection COVID-19. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2021;121(12):33-39. (In Russ.). https://doi.org/10.17116/jnevro202112112133
  9. Tereshin AE, Kiryanova VV, Reshetnik DA. Correction of mitochondrial dysfunction in the complex rehabilitation of COVID-19. Zhurnal nevrologii ipsikhiatrii im. S.S. Korsakova.2021;121(8):25-29. (In Russ.). https://doi.org/10.17116/jnevro202112108125
  10. Agaf’ina AS, Makar’ina ES, Usikova EV, Shcherbak SG, Mineev KK. Neuroprotective therapy in the rehabilitation of patients who have suffered COVID-19 associated pneumonia. Jeksperimental’naya i klinicheskaya farmakologiya. 2022;85(1):7-12. (In Russ.). https://doi.org/10.30906/0869-2092-2022-85-1-7-12
  11. Putilina MV, Teplova NV, Bairova KI, Petrikeeva AE, Shabalina NI. The results of prospective randomized study CITADEL ‒ the efficacy and safety of drug Cytoflavin in postcovid rehabilitation. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2021;121(10):45-51. (In Russ.). https://doi.org/10.17116/jnevro202112110145
  12. Belova LA, Mashin VV, Dolgova DR, Kuvaiskaya AA, Kruglova LR, Sukhikh SS, Plaksina TD. Evaluation of the effectiveness of the drug Cytoflavin in patients with dyscirculatory encephalopathy who have undergone a new coronavirus infection. Zhurnal nevrologii i psikhiatrii im.S.S. Korsakova. 2023;123(6):1-9. (In Russ.). https://doi.org/10.17116/jnevro202312306163
  13. Alenskaya TL. Innovative methods of rehabilitation at the outpatient and home stages in patients after pneumonia COVID-19. Meditsinski ysovet. 2021;(4):220-229. (In Russ.). https://doi.org/10.21518/2079-701X-2021-4-220-229
  14. Clinical Practice guidelines Chronic fatigue syndrome. Produced by a Working Group convened under the auspices of the Royal Australian College of Physicians. Medical Journal of Australia. 2002;8(suppl):17-55. 
  15. Komaroff AL, Lipkin WI. Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of postacute COVID-19 syndrome. Trends in Molecular Medicine. 2021;27(9):895-906.  https://doi.org/10.1016/j.molmed.2021.06.002
  16. Cusumano ZT, Watson ME Jr, Caparon MG. Streptococcus pyogenes arginine and citrulline catabolism promotes infection and modulates innate immunity. Infection and Immunity. 2014;82(1):233-242.  https://doi.org/10.1128/IAI.00916-13
  17. Aguayo E, Martínez Sánchez A, Fernández-Lobato B, Alacid F. L-Citrulline: A Non-Essential Amino Acid with Important Roles in Human Health. Applied Sciences. 2021;11:3293. https://doi.org/10.3390/app11073293
  18. Sureda A, Córdova A, Ferrer MD, Pérez G, Tur JA, Pons A. L-Citrulline-malate influence over branched chain amino acid utilization during exercise. European Journal of Applied Physiology. 2010;110:341-351.  https://doi.org/10.1007/s00421-010-1509-4
  19. Takeda K, Machida M, Kohara A, Omi N, Takemasa T. Effects of citrulline supplementation on fatigue and exercise performance in mice. Journal of Nutritional Science and Vitaminology. 2011;57:246-250.  https://doi.org/10.3177/jnsv.57.246
  20. Bescós R, Sureda A, Tur JA, Pons A. The Effect of Nitric-Oxide-Related Supplements on Human Performance. Sports Medicine (Auckland, N.Z.). 2012;42:99-117.  https://doi.org/10.2165/11596860-000000000-00000
  21. Gonzales JU, Raymond A, Ashley J, Kim Y. Doesl-citrulline supplementation improve exercise blood flow in older adults? Experimental Physiology. 2017;102:1661-1671. https://doi.org/10.1113/EP086587
  22. Torshin IYu, Gromova OA, Fedotova LE, Gromov AN, Rudakov KV. Chemoreactomic analysis of citrulline and malate molecules. Nevrologija, nejropsihiatrija, psihosomatika. 2017;9(1):30-35. (In Russ.). https://doi.org/10.17116/jnevro202112103260
  23. Startseva SE, Krasavina NA. Evaluation of the effectiveness of rehabilitation measures in children at risk of long-term and often ill. Zdorov’e sem’i — 21 vek. 2013;1:184-192.(In Russ.).
  24. Volosovets AP. Optimization of asthenia pharmacotherapy in the practice of modern pediatrics. Praktika pediatra. 2012;2:23-28. (In Russ.).
  25. Commandré F. Analyse de l’activitedu Stimol. Essaisen double aveugle surl’asthenie. Vie Med. 1978;12:1084-1085.
  26. Voronina TA. Antioxidants/antihypoxants ‒ the missing puzzle of effective pathogenetic therapy of patients with COVID-19. Infekcionnye bolezni. 2020; 18(2):97-102. (In Russ.). https://doi.org/10.20953/1729-9225-2020-2-97-102
  27. Shchulkin AV. Modern ideas about the antihypoxic and antioxidant effect of mexidol. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2018;12(2): 87-93. (In Russ.). https://doi.org/10.17116/jnevro201811812287
  28. Kovalchuk VV, Ershova II, Molodovskaya NV. Possibilities of improving the effectiveness of therapy in patients with chronic cerebral ischemia against the background of COVID-19. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2021;121(3-2):60-66. (In Russ.). https://doi.org/10.17116/jnevro202112103260
  29. Poverennova IE, Zolotovskaia IA, Bezgina EV. Diagnosis and treatment of asthenic syndrome in elderly people who have had ARVI. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2014;114(9):73-76. (In Russ.).
  30. Fedin AI, Zakharov VV, Tanashyan MM, Chukanova EI, Majidova EN, Shchepankevich LA, Ostroumova OD. Results of an international multicenter randomized double-blind placebo-controlled study evaluating the efficacy and safety of sequential therapy of patients with chronic cerebral ischemia with Mexidol and Mexidol FORTE 250 (MEMO study). Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2021;121(11):7-16. (In Russ.). https://doi.org/10.17116/jnevro20211211117
  31. Wesselink E, Koekkoek WAC, Grefte S, Witkamp RF, van Zanten ARH. Feeding mitochondria: Potential role of nutritional components to improve critical illness convalescence. Clinical Nutrition (Edinburgh, Scotland). 2019; 38(3):982-995.  https://doi.org/10.1016/j.clnu.2018.08.032
  32. Romanova EN, Govorin AV, Serebryakova OM. The state of convalescents after influenza A/P1/T1 complicated by pneumonia. Sibirskiy medicinskiy zhurnal. 2011;4:73-75. (In Russ.).
  33. Studenikin VM, Tursunkhuzhaeva SSh, Pak LA, Shelkovsky VI. Levocarnitine (Elkar) in epileptology and neuropediatrics. Jeffektivnaya farmakoterapiya. Pediatriya. 2011;90(6):22-25. (In Russ.).
  34. Kalinina MA, KozlovskayaGV, Kremneva LF. Levocarnitine in children’s practice. RMZh. Medicinskoe obozrenie. 2018;10:40-44. (In Russ.).
  35. DiNicolantonio JJ, Lavie CJ, Fares H, Menezes AR, O’Keefe JH. L-carnitine in the secondary prevention of cardiovascular disease: systematic review and meta-analysis. Mayo Clinic Proceedings. 2013;88(6):544-551.  https://doi.org/10.1016/j.mayocp.2013.02.007
  36. Khoroshilov I. Carnitine: the role in the body and the possibilities of therapeutic use in various diseases. Vrach. 2017;(3):2-6. (In Russ.).
  37. Dinicolantonio JJ, Niazi AK, McCarty MF, Lavie CJ, Liberopoulos E, O’Keefe JH. L-carnitine for the treatment of acute myocardial infarction. Reviews in Cardiovascular Medicine. 2014;15(1):52-62. 
  38. Semigolovsky NYu, Vertsinsky EK, Azanov BA, Ivanova EV. Positive inotropic properties of L-carnitine in small ejection syndrome in patients with acute myocardial infarction. Kardiologija i serdechno-sosudistaya khirurgiya. 2013;3:43-46. (In Russ.).
  39. Glezer MG, Kiseleva AE, Astashkin EI. The effect of L-carnitine on heart rate and QT in patients with acute coronary syndrome. Serdce. 2015;14:78-84 (In Russ.).
  40. Lee BJ, Lin JS, Lin YC, Lin PT. Antiinflammatory effects of L-carnitine supplementation (1000 mg/d) in coronary artery disease patients. Nutrition (Burbank, Los Angeles County, Calif.). 2015;31(3):475-479.  https://doi.org/10.1016/j.nut.2014.10.001
  41. Golovkin V, Zuev A, Privalova M, Abakarov Sh. Cognitive impairment and cardiorespiratory dysfunction in dyscirculatory encephalopathy with cardiocerebral syndrome. Vrach. 2018;29(4):51-53. (In Russ.). https://doi.org/10.29296/25877305-2018-04-09
  42. Morozov PV. New in the treatment of asthenia. Psihiatrija i psihofarmakoterapija. 2005;3:154-159. (In Russ.).
  43. Vane AM, Fedotova AV, Gordeev SA. Enerion in the treatment of asthenia in the framework of psychovegetative syndrome. Lechenye nervnykh boleznej. 2003;2:9. (In Russ.).
  44. Carmen Helena Acevedo. Astenia en pacientes que asisten a la consulta externa. Valoracion a traves de la escala de intensidad de fatiga (FSS). Archivos Venezolanos de Farmacología y Terapéutica. 2012;31(3):62-66. 
  45. Vane AM, Fedotova AV, Gordeev SA. Enerion is an effective and safe remedy for the treatment of asthenia in patients with psychovegetative syndrome. RMZH. 2004;10:631-634. (In Russ.).Accessed August 23, 2023. https://www.rmj.ru/articles/psikhiatriya/Enerion_-_effektivnoe_i_bezopasnoe_sredstvo_dlya_lecheniya_astenii_u_bolynyh_s_psihovegetativnym_sindromom/
  46. Tiev KP, Cabane J, Imbert JC. Traitement de l’asthenie en periode postinfectieuse: etude randomisee en double aveugle de deux doses de sulbutiamine (400-600 mg/j) versus placebo. La Revue de Medecine Interne. 1999;20: 912-918.  https://doi.org/10.1016/s0248-8663(00)80096-x
  47. Shah SN. Adjuvant role of vitamin B analogue (Sulbutiamine) with Anti-Infective Treatment in Infection Associated Asthenia. The Journal of the Association of Physicians of India. 2003;51:891-895. 
  48. Israel L, Dell’accio E, Hugonot R. Arcalion 200 et Entrainement mental «Interet d’Arcalion 200 chez les personnes agees astheniques». J Med Prat. 1989;3(suppl Oct.):19-24. 
  49. Frolova YuF, Gorlanova NM, Listradenkova DG, Amon EP, Malinnikova EYu. The results of an observational post-registration study of the efficacy and safety of the drug Trecresan in adult patients with acute respiratory viral infection. Terapija. 2021;8:172-181. (InRuss.).
  50. Zueva IB, Kim YuV, Suslova MYu. How to optimize the management of patients with postinfectious asthenia who have undergone COVID-19 at the outpatient stage? Terapiya. 2021;6:156-162. (In Russ.).
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