PURPOSE OF THE STUDY

To develop additional sensitive and specific electrocardiographic (ECG) criteria for the early diagnosis of left ventricular hypertrophy (LVH).

MATERIAL AND METHODS

The observation group consisted of 184 male patients (mean age 53.0±7.5 years). Echocardiography (ECHO-KG) was performed using a Vivid q device (GE Vingmed Ultrasound AS, Norway) to determine LVH, ECG in 12 standard leads using a CARDIOVIT AT-10 electrocardiograph (Schiller FG, Switzerland) to assess LVH indices. Statistical data processing and ROC analysis were performed.

RESULTS

In the examined cohort, according to ECG data, LVH was registered only in 7.1% of patients, according to transthoracic echocardiography — in 45.6% of patients. Good predictive power for LVH diagnosis is shown for Cornell voltage index (AUC=0.744), average for RaVL (AUC=0.679). According to the ROC analysis matrix, the RaVL cut-off value for LVH is 4.5 mm with a sensitivity of 71% and a specificity of 56%; for the Cornell voltage index, this value is 15.5 mm with a sensitivity of 74% and a specificity of 57%. When assessing the cut-off point (cut-off) of the left ventricular myocardial mass index (LVMMI) by growth to the power of 2.7 in relation to predictive belonging to the LVH group according to the two-factor logistic regression model, the value of AUC=0.704 (p=0) was obtained using the ROC-analysis method..0001) and LVMMI cutoff points with a sensitivity of 68% and a specificity of 72% equal to 50 g/m^2.7.

CONCLUSION

The established cut-off points for left ventricular hypertrophy in men for RaVL 4.5 mm and Cornell voltage index 15.5 mm make it possible to predict the presence of left ventricular hypertrophy in men and to carry out targeted echocardiography.