In recent years, regional executive bodies and health authorities have paid much attention to the prevention of chronic noncommunicable diseases (CNCDs) and to the formation of healthy lifestyle (HLS) among the population in the north of the Russian Federation (RF). Objective — to study how the regional state policy on the prevention of CNCDs and the formation of HLS is implemented in the regions of the Russian North. This will be able to identify best practices, innovative techniques and mechanisms for working with different population segments for their further replication in order to improve the population’s health not only in the northern territories, but also in other subjects of the RF. Material and methods. The empirical basis for a comparative analysis was the 2015 annual public health and health care reports of six regional health authorities in the Russian North: the Yamal-Nenets Autonomous District, the Republic of Sakha (Yakutia), the Arkhangelsk Region, the Republic of Komi, the Krasnoyarsk Territory, and the Murmansk Region, as well as the websites of the Ministries of Health of these six subjects of the RF. Conclusion. The authors have identified main promising areas to improve regional and local programs and initiatives aimed at promoting HLS and preventing early CNCDs in the rural and remote areas of the Russian North. These are, above all, to strengthen the role of leading governmental health institutions in the regions, which coordinate work on preventive activities and on the formation of health-saving behavior; to set up, on their initiative, coordinating councils for interdepartmental and intradepartmental interaction; to attract broad population masses to actively participate in the events on world and national health and disease control days; and to use current and interactive technologies to work with young people.