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Vitiazeva I.I.

FGBU Éndokrinologicheskiĭ nauchnyĭ tsentr Minzdravsotsrazvitiia Rossiĭskoĭ Federatsii

Barmina I.I.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr, Moskva

Bogoliubov S.V.

FGBU "Éndokrinologicheskiĭ nauchnyĭ tsentr" Minzdrava RF, Moskva

Altashina M.V.

FGBU "ndokrinologicheskiĭ nauchnyĭ tsentr" Minzdrava Rossii, Moskva

Liutyi R.U.

Endocrinology Research Centre Ministry of Healthcareof the Russian Federation Moscow, Russia, 117036

Mun T.V.

Endocrinology Research Centre, Moscow, Russia

Razina O.U.

Endocrinology Research Centre Ministry of Healthcareof the Russian Federation Moscow, Russia, 117036

Dedov I.I.

Endocrinology Research Centre

Spermatozoa functional maturity markers in primary ejaculate assessment

Authors:

Vitiazeva I.I., Barmina I.I., Bogoliubov S.V., Altashina M.V., Liutyi R.U., Mun T.V., Razina O.U., Dedov I.I.

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Journal: Russian Journal of Human Reproduction. 2017;23(1): 90‑95

DOI: 10.17116/repro201723190-95

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SPERMATOZOA FUNCTIONAL MATURITY MARKERS IN PRIMARY EJACULATE ASSESSMENT
SPERMATOZOA FUNCTIONAL MATURITY MARKERS IN PRIMARY EJACULATE ASSESSMENT

To cite this article:

Vitiazeva II, Barmina II, Bogoliubov SV, et al. . Spermatozoa functional maturity markers in primary ejaculate assessment. Russian Journal of Human Reproduction. 2017;23(1):90‑95. (In Russ.)
https://doi.org/10.17116/repro201723190-95

 
 
Подписка 2025-2 (Russian Journal of Human Reproduction)
 
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Objective. To compare the HBA-test results in patients with normozoospermia and pathozoospermia and to assess the basic parameters of semen analysis in which the HBA-test can be used. Material and methods. Semen analysis and HBA-test were performed in 102 patients. Patients were divided into two groups: group 1 (54 men) with normozoospermia, group 2 (48) with pathozoospermia. All patients were stratified in 8 groups with descending results of the HBA-test to receive the prognostic values for concentration, motility and morphology of spermatozoa according to HBA-test. Results. The average concentration of spermatozoa in groups 1 and group 2 were 76.7±7.26×106 and 32.3±6.39×106/ml, respectively. Sperm motility in Group 1 was 54.7±1.78% and in Group 2 it was 32.4±4.00%. Significant differences were statistically obtained by analyzing the HBA-test results in comparison groups. Possible predictors for HBA-test assignment was the concentration of ≤41·106/ml, progressive motility ≤38%, standard morphology ≤3%. Conclusions. The data showed a significant reduction of HBA-test results in the pathozoospermia group. Analysis of hyaluronan binding in the patients who have semen analysis results equal or lower than sperm predictors may help to improve the effectiveness of IVF programs.

Keywords:

sperm
semen analysis
HBA-test
hyaluronan

Authors:

Vitiazeva I.I.

FGBU Éndokrinologicheskiĭ nauchnyĭ tsentr Minzdravsotsrazvitiia Rossiĭskoĭ Federatsii

Barmina I.I.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr, Moskva

Bogoliubov S.V.

FGBU "Éndokrinologicheskiĭ nauchnyĭ tsentr" Minzdrava RF, Moskva

Altashina M.V.

FGBU "ndokrinologicheskiĭ nauchnyĭ tsentr" Minzdrava Rossii, Moskva

Liutyi R.U.

Endocrinology Research Centre Ministry of Healthcareof the Russian Federation Moscow, Russia, 117036

Mun T.V.

Endocrinology Research Centre, Moscow, Russia

Razina O.U.

Endocrinology Research Centre Ministry of Healthcareof the Russian Federation Moscow, Russia, 117036

Dedov I.I.

Endocrinology Research Centre

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