Leukemia inhibitory factor and endometrial receptivity

Leviashvili M.M.; Mishieva N.G.; Nazarenko T.A.; Kogan E.A.

doi:https://doi.org/

Leviashvili M.M.

FGU "Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova" Minzdravsotsrazvitiia Rossii, Moskva

Mishieva N.G.

FGU "Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova" Minzdravsotsrazvitiia Rossii, Moskva

Nazarenko T.A.

Kafedra akusherstva, ginekologii, perinatologii i reproduktologii fakul'teta poslediplomnogo professional'nogo obucheniia vracheĭ Moskovskoĭ meditsinskoĭ akademii im. I.M. Sechenova;
Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova

Kogan E.A.

Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova, Moskva

Leukemia inhibitory factor and endometrial receptivity

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Leviashvili M.M., Mishieva N.G., Nazarenko T.A., Kogan E.A.

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Journal: Russian Journal of Human Reproduction. 2012;(3): 17‑21

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To cite this article:

Leviashvili MM, Mishieva NG, Nazarenko TA, Kogan EA. Leukemia inhibitory factor and endometrial receptivity. Russian Journal of Human Reproduction. 2012;(3):17‑21. (In Russ.)

Подписка 2026 Проблемы репродукции (Russian Journal of Human Reproduction)

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Abstract:

We studied LIF in the endometrium tissue and cervical mucus (CM) during implantation window in 79 infertile patients with multiple IVF failures and 8 fertile women of reproductive age. That average normal concentration of LIF in CM was 20±8.6 pg/ml. The increasing over 45 g/ml is associated with chronic endometritis. LIF expression is predominant in the stroma of the endometrium in patients with chronic endometritis. The measurement of LIF concentration study in the cervical mucus seems to be informative and non-invasive method of endometrium receptivity assessment.

Keywords:

LIF

endometrium receptivity

cervical mucu

Authors:

Leviashvili M.M.

FGU "Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova" Minzdravsotsrazvitiia Rossii, Moskva

Mishieva N.G.

FGU "Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova" Minzdravsotsrazvitiia Rossii, Moskva

Nazarenko T.A.

Kogan E.A.

Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova, Moskva

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