The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Rakhimov A.Ya.

Institute of Plastic surgery and Cosmetology

Fayzullin T.R.

Moscow Regional Research and Clinical Institute

Vasilyev V.S.

Center of plastic and aesthetic surgery PLASTES

Sergeev I.V.

Moscow Regional Research and Clinical Institute

Lipofilling safety: mechanisms, prevention and treatment of severe complications of injectable adipose tissue transplantation

Authors:

Rakhimov A.Ya., Fayzullin T.R., Vasilyev V.S., Sergeev I.V.

More about the authors

Journal: Plastic Surgery and Aesthetic Medicine. 2020;(4): 73‑78

DOI: 10.17116/plast.hirurgia202004173

Read: 7273 times

Download PDF (RU)
Contact the author
Table of contents

LIPOFILLING SAFETY: MECHANISMS, PREVENTION AND TREATMENT OF SEVERE COMPLICATIONS OF INJECTABLE ADIPOSE TISSUE TRANSPLANTATION
LIPOFILLING SAFETY: MECHANISMS, PREVENTION AND TREATMENT OF SEVERE COMPLICATIONS OF INJECTABLE ADIPOSE TISSUE TRANSPLANTATION

To cite this article:

Rakhimov AYa, Fayzullin TR, Vasilyev VS, Sergeev IV. Lipofilling safety: mechanisms, prevention and treatment of severe complications of injectable adipose tissue transplantation. Plastic Surgery and Aesthetic Medicine. 2020;(4):73‑78. (In Russ.)
https://doi.org/10.17116/plast.hirurgia202004173

Подписка 2026 Пластическая хирургия и эстетическая медицина (Plastic Surgery and Aesthetic Medicine)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
CCL method in lower limb contouring. Plastic Surgery and Aesthetic Medi­cine. 2024;(4):39-45
Simu­ltaneous closure of plantar exte­nsive soft tissue defect using skin graft and lipo­filling after rese­ction of mela­noma. Plastic Surgery and Aesthetic Medi­cine. 2024;(4-2):86-90
Fat grafting for breast shaping after implant remo­val. Plastic Surgery and Aesthetic Medi­cine. 2025;(2):61-69
Resu­lts of replacing exte­nsive nerve defe­cts with synthetic conduits based on poly­lactide with poly­pyrrole in an expe­riment. Russian Journal of Operative Surgery and Clinical Anatomy. 2024;(4-2):24-32
Auto­logous fat transplantation into post-lymphadenectomy cavity for prevention of lymphorrhea after total mastectomy. Piro­gov Russian Journal of Surgery. 2025;(7):24-35
Abstract:

OBJECTIVE

To review the modern data on major complications following fat grafting; to analyze the incidence, causes, prevention and treatment of these complications.

MATERIAL AND METHODS

We have analyzed 22 references on major complications of fat grafting. The most dangerous complications followed by high risk of mortality and irreversible severe functional and aesthetic injury were distinguished. Statistical data, possible mechanisms, prevention and treatment were described.

RESULTS

Venous embolism, arterial embolism, nerve injury and major infection are the most dangerous adverse events following fat grafting. These conditions were comprehensively described. Safety of fat injections in cancer patients was discussed as well.

CONCLUSION

Recent scientific data on the most dangerous complications of fat grafting were summarized in this manuscript. Understanding the causes and mechanisms is essential to elaborate certain safety criteria of lipofilling in various anatomical areas. Correct lipofilling technique increases clinical safety of this procedure.

Keywords:

fat grating
lipofilling
brazilian butt lift
major complications
venous embolism
arterial embolism
nerve injury
oncological safety

Authors:

Rakhimov A.Ya.

Institute of Plastic surgery and Cosmetology

Fayzullin T.R.

Moscow Regional Research and Clinical Institute

Vasilyev V.S.

Center of plastic and aesthetic surgery PLASTES

Sergeev I.V.

Moscow Regional Research and Clinical Institute

Received:

09.07.2020

Accepted:

27.07.2020

Close metadata

References:

  1. ISAPS. Patient Alert: Gluteal Fat Grafting to the Buttocks is a High Risk Cosmetic Surgery Procedure Warns International Society of Aesthetic Plastic Surgery. New York, NY: 2018. Accessed September 20, 2020. https://www.premierphysicianmarketing.com/
  2. Rios L, Gupta V. Improvement in Brazilian Butt Lift (BBL) Safety With the Current Recommendations from ASERF, ASAPS, and ISAPS. Aesthet Surg J. 2020;40(8):864-870.  https://doi.org/10.1093/asj/sjaa098
  3. Mofid MM, Teitelbaum S, Suissa D, Ramirez-Montañana A, Astarita DC, Mendieta C, Singer R. Report on mortality from gluteal fat grafting: recommendations from the ASERF Task Force. Aesthet Surg J. 2017;37(7):796-806.  https://doi.org/10.1093/asj/sjx004
  4. Conde-Green A, Cansancao AL, Rosique RG, Rosique MJ, Cervantes A. Brazilian Butt Lift Performed by Brazilian Plastic Surgeons: Reports of an Expert Opinion Survey. Plast Reconstr Surg Glob Open. 2018;6(9):82-83. 
  5. Wall S, Del Vecchio D. Commentary on: Report on mortality from gluteal fat grafting: recommendations from the ASERF Task Force. Aesthet Surg J. 2017;37(7):807-810.  https://doi.org/10.1093/asj/sjx080
  6. Del Vecchio D, Villanueva NL, Mohan R, Johnson B, Wan D, Venkataram A, Rohrich RJ. Clinical implications of gluteal fat graft migration: a dynamic anatomical study. Plast Reconstr Surg. 2018;142(5):1180-1192. https://doi.org/10.1097/PRS.000000000000502
  7. Wall S, Del Vecchio D, Teitelbaum S, Villanueva NL, Dayan E, Durand P, Sanniec K, Rochrich RJ. Subcutaneous migration: a dynamic anatomical study of gluteal fat grafting. Plast Reconstr Surg. 2019;143(5):1343-1351. https://doi.org/10.1097/PRS.0000000000005521
  8. Villanueva NL, Del Vecchio DA, Afrooz PN, Carboy JA, Rohrich RJ. Staying safe during gluteal fat transplantation. Plast Reconstr Surg. 2018;141(1):79-86.  https://doi.org/10.1097/PRS.000000000000393
  9. Del Vecchio D, Wall S. Expansion Vibration Lipofilling: A New Technique in Large — Volume Fat Transplantation. Plast Reconstr Surg. 2018;141(5):639-649. 
  10. Wall S, Lee MR. Separation, Aspiration, and Fat Equalization: SAFE Liposuction Concepts for Comprehensive Body Contouring. Plast Reconstr Surg. 2016;138(6):1192-1201. https://doi.org/10.1097/PRS.000000000000280
  11. Alvarez-Alvarez FA, González-Gutiérrez HO, Ploneda-Valencia CF. Safe Gluteal Fat Graft Avoiding a Vascular or Nervous Injury: An Anatomical Study in Cadavers. Aesthet Surg J. 2019;39(2):174-184. 
  12. Turin SY, Fracol M, Keller E, Markl M, Collins J, Krochmal D, Kim JY. Gluteal Vein Anatomy: Location, Caliber, Impact of Patient Positioning, and Implications for Fat Grafting. Aesthet Surg J. 2020;40(6):642-649.  https://doi.org/10.1093/asj/sjz26
  13. Cansancao AL, Condé-Green A, Vidigal RA, Rodriguez RL, D’Amico RA. Real-Time Ultrasound-Assisted Gluteal Fat Grafting. Plast Reconstr Surg. 2018;142(2):372-376.  https://doi.org/10.1097/PRS.0000000000004602
  14. Vasilakis V, Hamade M, Stavrides SA, Davenport TA. Bilateral sciatic neuropathy following gluteal augmentation with autologous fat grafting. Plast Reconstr Surg Glob Open. 2018;6(3):e1696. https://doi.org/10.1097/GOX.0000000000001696
  15. Coleman SR, Mazzola RF, Lee LQ. Fat injection. From filling to regeneration. 2nd ed. New York: Thieme; 2018.
  16. Yu NZ, Huang JZ, Zhang H, Wang Y, Wang XJ, Zhao R, Bai M, Long X. A Systemic Review of Autologous Fat Grafting Survival Rate and Related Severe Complications. Chin Med J (Engl). 2015;128(9):1245-1251. https://doi.org/10.4103/0366-6999.156142
  17. Pek CH, Lim J, Ng HW, Lee HJ, Ong WC, Foo ATL, Lim CM, Thong M, Sebastin SJ, Lim TC. Extensive necrotizing fasciitis after fat grafting for bilateral breast augmentation: recommended approach and management. Arch Plast Surg. 2015;42(3):365-367.  https://doi.org/10.5999/aps.2015.42.3.365
  18. Kim SK, Choi JA, Kim MH, Kim MS, Lee KC. Treatment of the Mycobacterium chelonae Infection after Fat Injection. Arch Plast Surg. 2015;42(1): 68-72.  https://doi.org/10.5999/aps.2015.42.1.68
  19. Groen JW, Negenborn VL, Twisk WR, Rizopoulos DJ, Ket CF, Smit JM, Mullender MG. Autologous Fat Grafting in Onco-Plastic Breast Reconstruction: A Systematic Review on Oncological and Radiological Safety, Complications, Volume Retention and patient/surgeon Satisfaction. J Plast Reconstr Aesthet Surg. 2016;69(6):742-764.  https://doi.org/10.1016/j.bjps.2016.03.019
  20. Krastev TK, Schop SJ, Hommes J, Piatkowski AA, Heuts EM, van der Hulst RRWJ. Meta-analysis of the oncological safety of autologous fat transfer after breast cancer. Br J Surg. 2018;105(9):1082-1097. https://doi.org/10.1002/bjs.10887
  21. Silva MM, Kokai LE, Donnenberg VS, Fine JL, Marra KG, Donnenberg AD, Neto MS, Rubin JP. Oncologic Safety of Fat Grafting for Autologous Breast Reconstruction in an Animal Model of Residual Breast Cancer. Plast Reconstr Surg. 2019;143(1):103-112.  https://doi.org/10.1097/PRS.0000000000005085
  22. Gebremeskel S, Gencarelli J, Gareau AJ, Levatte T, Dugandzic A, Johnston B, Bezuhly M. Promotion of Primary Murine Breast Cancer Growth and Metastasis by Adipose-Derived Stem Cells Is Reduced in the Presence of Autologous Fat Graft. Plast Reconstr Surg. 2019;143(1):137-147.  https://doi.org/10.1097/PRS.0000000000005142
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.