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Trandofilov M.M.

P.A. Herzen Moscow Oncology Research Institute — Branch of National Medical Radiological Centre;
Russian University of Medicine

Trifanov V.S.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Grishin N.A.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Popov A.Y.

A.V. Vishnevsky National Medical Research Center of Surgery

Kostirev S.V.

Russian University of Medicine

Sizova A.N.

Russian University of Medicine

Mirzaev T.S.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Chernichenko M.A.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Ibraimov N.U.

P.A. Herzen Moscow Oncology Research Institute — Branch of National Medical Radiological Centre

Vakhromkin V.S.

Russian University of Medicine

Teryasov S.G.

Russian University of Medicine

Experience of using laser ablation in the surgical treatment of malignant liver tumors

Authors:

Trandofilov M.M., Trifanov V.S., Grishin N.A., Popov A.Y., Kostirev S.V., Sizova A.N., Mirzaev T.S., Chernichenko M.A., Ibraimov N.U., Vakhromkin V.S., Teryasov S.G.

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Journal: P.A. Herzen Journal of Oncology. 2024;13(3): 40‑45

DOI: 10.17116/onkolog20241303140

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Table of contents

EXPERIENCE OF USING LASER ABLATION IN THE SURGICAL TREATMENT OF MALIGNANT LIVER TUMORS
EXPERIENCE OF USING LASER ABLATION IN THE SURGICAL TREATMENT OF MALIGNANT LIVER TUMORS

To cite this article:

Trandofilov MM, Trifanov VS, Grishin NA, et al. . Experience of using laser ablation in the surgical treatment of malignant liver tumors. P.A. Herzen Journal of Oncology. 2024;13(3):40‑45. (In Russ.)
https://doi.org/10.17116/onkolog20241303140

Подписка 2026 Онкология. Журнал им. П.А. Герцена (P.A. Herzen Journal of Oncology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

OBJECTIVE

Analysis of the results of treatment of patients with metastatic liver tumors using laser ablation.

MATERIAL AND METHODS

Results of treatment of 27 patients with metastatic liver lesions who underwent laser ablation for the period from March, 2017 to January 2023, were analyzed. The size of lesions was 10—40 mm, average size — 29.8±1.7 mm). Laser destruction was performed percutaneously, with laparoscopic and open approaches under ultrasound scanning in real time mode. For laser ablation, an ECHO LASER X4 device (Italy) was used. Ultrasound, MRI and CT with intravenous contrast were used for the dynamically control of ablation effectiveness.

RESULTS

In the early postoperative period, in one case, the formation of a subcapsular hematoma was observed in the area of the light guide, which did not require surgical intervention. The average bed/day was 4 days. One-year overall survival stood at 88%, two-year overall survival stood at 71%, 3-years — 43.5%.

CONCLUSION

The use of laser ablation is indicated for insufficient functional liver volume in patients with previously extensive liver resections, and in somatically burdened patients who cannot undergo liver resection.

Keywords:

laser ablation
metastatic liver lesion

Authors:

Trandofilov M.M.

P.A. Herzen Moscow Oncology Research Institute — Branch of National Medical Radiological Centre;
Russian University of Medicine

Trifanov V.S.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Grishin N.A.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Popov A.Y.

A.V. Vishnevsky National Medical Research Center of Surgery

Kostirev S.V.

Russian University of Medicine

Sizova A.N.

Russian University of Medicine

Mirzaev T.S.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Chernichenko M.A.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Ibraimov N.U.

P.A. Herzen Moscow Oncology Research Institute — Branch of National Medical Radiological Centre

Vakhromkin V.S.

Russian University of Medicine

Teryasov S.G.

Russian University of Medicine

Received:

14.03.2023

Accepted:

11.05.2023

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References:

  1. Kaprin AD, Starinskii VV, Petrova GV. The state of oncological assistance for the population of Russia in 2021. M.: MNIOI im. P.A. Gertsena — filial FGBU «NMITs radiologii» Ministerstva zdravookhraneniya Rossiiskoi Federatsii; 2022. (In Russ.).
  2. Patyutko YuI, Kotel’nikov AG, Polyakov AN, Chuchuev ES, Ivanov AA, Podluzhnyi DV, Sagaidak IV, Shishkina NA, Mamontov KG, Agafonova MG. Surgical tactics in recurrent liver tumors. Vestnik Khirurgicheskoi Gastroenterologii. 2010;(4):10-21. (In Russ.).
  3. Cillo U, De Carlis L, eds. Liver transplantation and hepatobiliary surgery. Interplay of technical and theoretical aspects. Springer; 2020;236. 
  4. Skipenko OG, Shelygin YuA, Achkasov SI, eds. Metastaticheskii kolorektal’nyi rak. Moscow: Izdatel’stvo Del’ta Plyus; 2020. (In Russ.).
  5. Prazdnikov EN, Sizova AN, Svetashov VS, Zinatulin DR, Trandofilov MM, Rudakova MN, Popov AYu, Kostyrev SV, Prokhorov AV. Combined treatment of colorectal cancer followed by metastatic liver injury. Khirurgiya. Zhurnal im. N.I. Pirogova. 2018;(8):17-23. (In Russ.). https://doi.org/10.17116/hirurgia201808217
  6. Sizova AN. Mikrovolnovaya ablyatsiya v khirurgicheskom komponente kompleksnogo lecheniya metastaticheskogo porazheniya pecheni. Dis. ... kand. med. nauk. M. 2020. (In Russ.).
  7. Svetashov VS. Mikrovolnovaya ablyatsiya v khirurgicheskom komponente kompleksnogo lecheniya pervichnogo raka pecheni: Dis. ... kand. med. nauk. M. 2018. (In Russ.).
  8. De Costanzo GG, Tortora RD, D’Adamo J, De Luca M, Lampasi F, Addario L, Galeota Lanza A, Picciotto FP, Tartaglione MT, Cordone G, et al. Radiofrequency ablation versus laser ablation for the treatment of small hepatocellular carcinoma in cirrhosis: a randomized trial. J Gastroenterol Hepatol. 2015;30(3):559-565.  https://doi.org/10.1111/jgh.12791
  9. Kosyrev VYu, Dolgushin BI. Radiofrequency thermoablation in the treatment of patients with hepatocellular carcinoma and colorectal cancer liver metastases. Medical Radiology and Radiation Safety. 2011;56(3):54-61. (In Russ.).
  10. Ionkin DA, Zhavoronkova OI, Stepanova YuA, Gavrilov YaYa, Vishnevskii VA, Chzhao AV. Thermal methods of local destruction (RFA, Cryodestruction, Microwave ablation) in metastatic liver cancer. Aspirantskii Vestnik Povolzh’ya. 2018;(5-6):127-145. (In Russ.). https://doi.org/10.17816/2072-2354.2018.18.3.127-145
  11. Jiang T, Deng Z, Tian G, Chen F, Bao H, Li J, Wang W. Percutaneous laser ablation: a new contribution to unresectable high-risk metastatic retroperitoneal lesions? Oncotarget. 2017;8(2):2413-2422. https://doi.org/10.18632/oncotarget.13897
  12. Pacella MC, Jiang T, Mauri J. Image-guided laser ablation. Springer; 2020;160.  https://doi.org/10.1007/978-3-030-21748-8
  13. Chai W, Zhao Q, Song H, Cheng C, Tian G, Jiang T. Treatment response and preliminary efficacy of hepatic tumour laser ablation under the guidance of percutaneous and endoscopic ultrasonography. World J Surg Oncol. 2019;17(1):133.  https://doi.org/10.1186/s12957-019-1677-6
  14. Hackl C, Neumann P, Gerken M, Loss M, Klinkhammer-Schalke M, Schlitt HJ. Treatment of colorectal liver metastases in Germany: a ten-year population-based analysis of 5772 cases of primary colorectal adenocarcinoma. BMC Cancer. 2014;14:810.  https://doi.org/10.1186/1471-2407-14-810
  15. Gillams A, Goldberg N, Ahmed M, Bale R, Breen D, Callstrom M, Chen MH, Choi BI, de Baere T, Dupuy D, et al. Thermal ablation of colorectal liver metastases: a position paper by an international panel of ablation experts, The Interventional Oncology Sans Frontieres meeting 2013. Eur Radiol. 2015;25(12):3438-3454. https://doi.org/10.1007/s00330-015-3779-z
  16. William R. Blumgart’s surgery of liver, biliary tract and pancreas. 7th ed. 2 vol. Elsevier Health Sciences; 2022.
  17. Lu Z, Shen F, Yan ZL, Li J, Yang JH, Zong M, Shi LH, Wu MC. Treatment of portal vein tumor thrombus of hepatocellular carcinoma with percutaneous laser ablation. J Cancer Res Clin Oncol. 2009;135(6):783-789.  https://doi.org/10.1007/s00432-008-0513-0
  18. Liang P, Wang Y, Yu X, Dong B. Malignant liver tumors: treatment with percutaneous microwave ablation-complications among cohort of 1136 patients. Radiology. 2009;251(3):933-940.  https://doi.org/10.1148/radiol.2513081740
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