Bladder damage in locally advanced colorectal cancer

Likhter M.S.

A.N. Ryzhikh National Medical Research Center of Coloproctology of the Ministry of Health of Russia

Achkasov S.I.

State Research Centre of Coloproctology

Loran O.B.

Russian Medical Academy of Continuing Professional Education of the Ministry of Health of Russia

Reznitsky P.A.

A.N. Ryzhikh National Medical Research Center of Coloproctology of the Ministry of Health of Russia

Shelygin Yu.A.

Ryzhikh National Medical Research Centre for Coloproctology;
Russian Medical Academy of Continuous Professional Education

Bladder damage in locally advanced colorectal cancer

Authors:

Likhter M.S., Achkasov S.I., Loran O.B., Reznitsky P.A., Shelygin Yu.A.

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Journal: P.A. Herzen Journal of Oncology. 2021;10(4): 11‑17

DOI: 10.17116/onkolog20211004111

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To cite this article:

Likhter MS, Achkasov SI, Loran OB, Reznitsky PA, Shelygin YuA. Bladder damage in locally advanced colorectal cancer. P.A. Herzen Journal of Oncology. 2021;10(4):11‑17. (In Russ.)
https://doi.org/10.17116/onkolog20211004111

Подписка 2025-2 (P.A. Herzen Journal of Oncology)

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OBJECTIVE

To improve the quality of treatment in patients with bladder damage in locally advanced colorectal cancer.

SUBJECTS AND METHODS

From 1994 to 2012, surgical treatment results were retrospectively analyzed in 165 patients with bladder damage in locally advanced colorectal cancer at the A.N. Ryzhykh National Research Medical Center of Coloproctology. The patients were divided into clinical groups according to the volume of intervention. Group 1 (n=85) underwent bladder resection within the seromuscular layer; Group 2 (n=29) had sectoral bladder resection; Group 3 (n=35) subtotal bladder resection; and Group 4 (n=16) had cystectomy.

RESULTS

The 5-year survival rate was 57.6% in Group 1, 41.4% in Group 2, 40% in Group3, and 31.2% in Group 4. The volume of bladder resection did not affect the risk of local relapses and distant metastases. A high-grade tumor and metastatic lymph nodes were characterized by an unfavorable prognosis; the 5-year survival rate for these risk factors was 8.9%.

CONCLUSION

Organ-sparing operations on the bladder in patients with locally advanced colorectal cancer, even with its massive involvement in the tumor process, are oncologically appropriate and functionally acceptable.

Keywords:

locally advanced colorectal cancer

urinary bladder involvement

organ-sparing surgery

Authors:

Likhter M.S.

A.N. Ryzhikh National Medical Research Center of Coloproctology of the Ministry of Health of Russia

Achkasov S.I.

State Research Centre of Coloproctology

Loran O.B.

Russian Medical Academy of Continuing Professional Education of the Ministry of Health of Russia

Reznitsky P.A.

A.N. Ryzhikh National Medical Research Center of Coloproctology of the Ministry of Health of Russia

Shelygin Yu.A.

Ryzhikh National Medical Research Centre for Coloproctology;
Russian Medical Academy of Continuous Professional Education

Received:

23.04.2021

Accepted:

27.04.2021

List of references:

Bray F. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394-424. https://doi.org/10.3322/caac.21492
Kaprin AD, Starinskii VV, Petrova GV, eds. Malignant neoplasms in Russia in 2018 (morbidity and mortality). M.: MNIOI imeni P.A.Gertsena — filial FGBU «NMITs radiologii» Minzdrava Rossii; 2019. (In Russ.).
Kostjuk IP, Vasilev LA, Kostin AA, Kaprin AD. Multivisceral resection in complex treatment of pelvic tumors. Bulletin of Pirogov National Medical & Surgical Center=Vestnik Natsional’nogo mediko-khirurgicheskogo Tsentra im. N.I. Pirogova. 2016;11(1):108-116. (In Russ.).
Browne E, Lawrentschuk N, Jack GS, Davis NF. A systematic review and meta-analysis of the long-term outcomes of ileal conduit and orthotopic neobladder urinary diversion. Can Urol Assoc J. 2021;15(1):48-57. https://doi.org/10.5489/cuaj.6466
Kondo A, Sasaki T, Kitaguchi D, Tsukada Y, Nishizawa Y, Ito M. Resection of the urinary bladder for locally advanced colorectal cancer: a retrospective comparison of partial versus total cystectomy. BMC Surg. 2019;19(1):63. https://doi.org/10.1186/s12893-019-0522-8
Delacroix SE Jr, Winters JC. Bladder reconstruction and diversion during colorectal. Clin Colon Rectal Surg. 2010;23(2):113-118. https://doi.org/10.1055/s-0030-1254298
Cerruto MA, D’Elia C, Siracusano S, Saleh O, Gacci M, Cacciamani G, De Marco V, Porcaro AB, Balzarro M, Niero M, Lonardi C, Iafrate M, Bassi P, Imbimbo C, Racioppi M, Talamini R, Ciciliato S, Serni S, Carini M, Verze P, Artibani W. Health-related quality of life after radical cystectomy for bladder cancer in elderly patients with ileal orthotopic neobladder or ileal conduit: Results from a Multicentre cross-sectional study using validate questionnaires. Urol Int. 2018;100(3):346-352. https://doi.org/10.1159/000487644
Ghosh A, Somani BK. Recent trends in postcystectomy health-related quality of life (QoL) favors neobladder diversion: systematic review of the literature. Urology. 2016;93:22-26. https://doi.org/10.1016/j.urology.2015.12.079
Moeen AM, Safwat AS, Gadelmoula MM, Moeen SM, Abonnoor AEI, Abbas WM, ElGanainy EO, El-Taher AM. Health related quality of life after urinary diversion. Which technique is better? J Egypt Natl Canc Inst. 2018;30(3):93-97. https://doi.org/10.1016/j.jnci.2018.08.001

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