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Semiglazova T.Iu.

FGBU "NII onkologii im. N.N. Petrova" Minzdravsotsrazvitiia Rossii, Sankt-Peterburg

Semiglazov V.V.

N.N. Petrov Research Institute of Oncology, Ministry of Health of the Russian Federation, St. Petersburg, Russia

Filatova L.V.

FGBU "NII onkologii im. N.N. Petrova" Minzdravsotsrazvitiia Rossii, Sankt-Peterburg

Krivorot'ko P.V.

FGBU "NII onkologii im. N.N. Petrova" Minzdravsotsrazvitiia Rossii, Sankt-Peterburg

Paltuev R.M.

FGBU "NII onkologii im. N.N. Petrova" Minzdravsotsrazvitiia Rossii, Sankt-Peterburg

Latipova D.Kh.

FGBU "NII onkologii im. N.N. Petrova" Minzdravsotsrazvitiia Rossii, Sankt-Peterburg

Gershanovich M.L.

FGBU "NII onkologii im. N.N. Petrova" Minzdravsotsrazvitiia Rossii, Sankt-Peterburg

Metastatic breast cancer: Innovation targeted agents

Authors:

Semiglazova T.Iu., Semiglazov V.V., Filatova L.V., Krivorot'ko P.V., Paltuev R.M., Latipova D.Kh., Gershanovich M.L.

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Journal: P.A. Herzen Journal of Oncology. 2012;1(2): 94‑99

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Table of contents

METASTATIC BREAST CANCER: INNOVATION TARGETED AGENTS
METASTATIC BREAST CANCER: INNOVATION TARGETED AGENTS

To cite this article:

Semiglazova TIu, Semiglazov VV, Filatova LV, Krivorot'ko PV, Paltuev RM, Latipova DKh, Gershanovich ML. Metastatic breast cancer: Innovation targeted agents. P.A. Herzen Journal of Oncology. 2012;1(2):94‑99. (In Russ.)

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The paper considers the possibilities of overcoming resistance to drug treatment for metastatic breast cancer (MBC) by using the innovation targeted agents: pertuzumab and T-DM1 in patients with HER-2-positive MBC, including in those with its progression after trastuzumab-containing regimens and an anti-mTOR inhibitor (everolimus) in patients with hormone-dependent (estrogen receptor-positive) BC without HER2 amplification, who are resistant to nonsteroidal aromatase inhibitors.

Keywords:

metastatic breast cancer
trastuzumab
pertuzumab
T-DM1
everolimus

Authors:

Semiglazova T.Iu.

FGBU "NII onkologii im. N.N. Petrova" Minzdravsotsrazvitiia Rossii, Sankt-Peterburg

Semiglazov V.V.

N.N. Petrov Research Institute of Oncology, Ministry of Health of the Russian Federation, St. Petersburg, Russia

Filatova L.V.

FGBU "NII onkologii im. N.N. Petrova" Minzdravsotsrazvitiia Rossii, Sankt-Peterburg

Krivorot'ko P.V.

FGBU "NII onkologii im. N.N. Petrova" Minzdravsotsrazvitiia Rossii, Sankt-Peterburg

Paltuev R.M.

FGBU "NII onkologii im. N.N. Petrova" Minzdravsotsrazvitiia Rossii, Sankt-Peterburg

Latipova D.Kh.

FGBU "NII onkologii im. N.N. Petrova" Minzdravsotsrazvitiia Rossii, Sankt-Peterburg

Gershanovich M.L.

FGBU "NII onkologii im. N.N. Petrova" Minzdravsotsrazvitiia Rossii, Sankt-Peterburg

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