Resection of sternum body with anterior segments of ribs II—III and bone replacement with individual titanium implant

Kharagezov D.A.; Mirzoyan E.A.; Stateshny O.N.; Antonyan A.A.; Leyman I.A.; Iozefi K.D.

doi:https://doi.org/10.17116/hirurgia202501168

Kharagezov D.A.

National Medical Research Centre of Oncology

ORCID: 0000-0003-0640-2994

Mirzoyan E.A.

National Medical Research Centre of Oncology

ORCID: 0000-0002-0328-9714

Stateshny O.N.

National Medical Research Centre of Oncology

ORCID: 0000-0003-4513-7548

Antonyan A.A.

National Medical Research Centre of Oncology

ORCID: 0000-0001-6449-7026

Leyman I.A.

National Medical Research Centre of Oncology

ORCID: 0000-0003-2572-1624

Iozefi K.D.

National Medical Research Centre of Oncology

ORCID: 0000-0002-5351-3251

Resection of sternum body with anterior segments of ribs II—III and bone replacement with individual titanium implant

Authors:

Kharagezov D.A., Mirzoyan E.A., Stateshny O.N., Antonyan A.A., Leyman I.A., Iozefi K.D.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2025;(1): 68‑73

DOI: 10.17116/hirurgia202501168

Read: 586 times

Contact the author

Table of contents

To cite this article:

Kharagezov DA, Mirzoyan EA, Stateshny ON, Antonyan AA, Leyman IA, Iozefi KD. Resection of sternum body with anterior segments of ribs II—III and bone replacement with individual titanium implant. Pirogov Russian Journal of Surgery. 2025;(1):68‑73. (In Russ.)
https://doi.org/10.17116/hirurgia202501168

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)

Использование инфографики авторами научных работ

Recommended articles:

Experience of using ribociclib in the therapy of metastatic breast cancer in a regional oncological dispensary. P.A. Herzen Journal of Oncology. 2025;(3):89-93

Abstract:

Metastatic breast cancer is the most common malignancy and urgent problem due to high mortality. This fact emphasizes the need for development of innovative surgical approaches. Innovative approaches, including 3D modeling, provide unique opportunities for accurate reconstruction of the sternum. This method promises significant progress in individualized treatment with higher effectiveness and survival. We present resection of sternum body with anterior segments of ribs II—III and bone replacement with individual titanium implant in a patient with metastatic breast cancer.

Keywords:

metastatic breast cancer

sternum resection

3D modeling of titanium implant

Authors:

Kharagezov D.A.

National Medical Research Centre of Oncology

ORCID: 0000-0003-0640-2994

Mirzoyan E.A.

National Medical Research Centre of Oncology

ORCID: 0000-0002-0328-9714

Stateshny O.N.

National Medical Research Centre of Oncology

ORCID: 0000-0003-4513-7548

Antonyan A.A.

National Medical Research Centre of Oncology

ORCID: 0000-0001-6449-7026

Leyman I.A.

National Medical Research Centre of Oncology

ORCID: 0000-0003-2572-1624

Iozefi K.D.

National Medical Research Centre of Oncology

ORCID: 0000-0002-5351-3251

Received:

21.03.2024

Accepted:

11.04.2024

Close metadata

References:

Nardin S, Mora E, Varughese FM, D’Avanzo F, Vachanaram AR, Rossi V, Saggia C, Rubinelli S, Gennari A. Breast Cancer Survivorship, Quality of Life, and Late Toxicities. Frontiers in Oncology. 2020;10:864. https://doi.org/10.3389/fonc.2020.00864
«Global Cancer Observatory» International Agency for Research on Cancer, Lyon, France. https://gco.iarc.fr/
Malignant neoplasms In Russia in 2021 (morbidity and mortality). Kaprin AD, Starinsky VV, Petrova GV, eds. Moscow: P.A. Herzen Moscow State Medical Research Institute, branch of the Federal State Budgetary Institution «NMIRC» of the Ministry of Health of the Russian Federation; 2022. (In Russ.).
Vladimirova LYu, Storozhakova AE, Snezhko TA, Strahova LK, Abramova NA, Kabanov SN, Kalabanova EA, Samaneva NYu, Svetickaya YaV, Tishina AV. Hormone-positive HER2-negative metastatic breast cancer: decision making in real-life clinical practice. South Russian Journal of Cancer. 2020;1(2):46-51. (In Russ.). https://doi.org/10.37748/2687-0533-2020-1-2-6
Kit OI, Vladimirova LYu, Kalabanova EA, Storozhakova AE, Kabanov SN, Snezhko TA, Mitashok IS, Svetickaya YaV, Samaneva NYu, Kornilova IS, Przhedeckij YuV, Pozdnyakova VV, Abramova NA, Popova IL, Tihanovskaya NM, L’yanova AA, Novoselova KA, Ryadinskaya LA. Opyt primeneniya pertuzumaba v protivoopuholevoj lekarstvennoj terapii her2-pozitivnogo raka molochnoj zhelezy. Sibirskij onkologicheskij zhurnal. 2021;20(2):85-92. (In Russ.). https://doi.org/10.21294/1814-4861-2021-20-2-85-92
D’Oronzo S, Silvestris E, Paradiso A, Cives M, Tucci M. Role of Bone Targeting Agents in the Prevention of Bone Metastases from Breast Cancer. International Journal of Molecular Sciences. 2020;21(8):3022. https://doi.org/10.3390/ijms21083022
Leto G. Current status and future directions in the treatment of bone metastases from breast cancer. Clinical and Experimental Pharmacology and Physiology. 2019;46(10):968-971. https://doi.org/10.1111/1440-1681.13139
Rebegea L, Ilie AM, Paslaru AM, Firescu D, Serban C, Voinescu C, Sapira V, Stoleriu G, Lungu M, Zgura A, Anghel R. Management of Epicardial Metastasis in Breast Cancer. Chirurgia. 2021;116(5):627-633. https://doi.org/10.21614/chirurgia.116.5.627
Kobayashi M, Tashima T, Nagata K, Sakuramoto S, Osaki A, Ryozawa S. Colorectal and gastric metastases from lobular breast cancer that resembled superficial neoplastic lesions. Clinical Journal of Gastroenterology. 2021;14(1):103-108. https://doi.org/10.1007/s12328-020-01285-3
Ding J, Guo Y, Jiang X, Li K, Fu W, Cao Y. Concomitant fulvestrant with reirradiation for unresectable locoregional recurrent estrogen receptor positive (ER+) breast cancer: A case report and narrative review. Medicine. 2020;99(30):e21344. https://doi.org/10.1097/MD.0000000000021344
Yoon YC, Lee J, Jeong JY. Radical resection and reconstruction of the sternum for metastasis of hepatocellular carcinoma. Journal of Cardio-Thoracic Surgery. 2020;15(1):202. https://doi.org/10.1186/s13019-020-01247-3
Young JS, McAllister M, Marshall MB. Three-dimensional technologies in chest wall resection and reconstruction. Journal of Surgical Oncology. 2023;127(2):336-342. https://doi.org/10.1002/jso.27164
Fernandez RAS, Lau RWH, Yu PSY, Siu ICH, Chan JWY, Ng CSH. Use of custom made 3-dimensional printed surgical guide for manubrio-sternal resection of solitary breast cancer metastasis: case report. AME Case Reports. 2020;4:12. https://doi.org/10.21037/acr.2020.03.08
Bennett DT, Weyant MJ. Extended chest wall resection and reconstruction in the setting of lung cancer. Thoracic Surgery Clinics. 2014;24(4):383-390. https://doi.org/10.1016/j.thorsurg.2014.07.002
Yang H, Tantai J, Zhao H. Clinical experience with titanium mesh in reconstruction of massive chest wall defects following oncological resection. Journal of Thoracic Disease. 2015;7(7):1227-1234. https://doi.org/10.3978/j.issn.2072-1439.2015.05.13
Jakoi A, Iorio J, Cahill PJ. Autologous bone graft harvesting: a review of grafts and surgical techniques. Musculoskelet Surgery. 2015;99(3):171-178. https://doi.org/10.1007/s12306-015-0351-6
Goldsmith I, Dovgalski L, Evans PL. 3D Printing Technology for Chest Wall Reconstruction With a Sternum-Ribs-Cartilage Titanium Implant: From Ideation to Creation. Innovations. 2023;18(1):67-72. https://doi.org/10.1177/15569845231153632
Clermidy H, Fadel G, De Lemos A, Pradere P, Mitilian D, Girault A, Menager JB, Fabre D, Mussot S, Leymarie N, Fadel E, Mercier O. Long-term outcomes after chest wall resection and repair with titanium bars and sternal plates. Frontiers in Surgery. 2022;9:950177. https://doi.org/10.3389/fsurg.2022.950177
Tukiainen E. Chest wall reconstruction after oncological resections. Scandinavian Journal of Surgery. 2013;102(1):9-13. https://doi.org/10.1177/145749691310200103