The necessity and importance of introducing the quality management system (QMS) in the framework of the modern approaches of organization of medical activities is not in doubt. In a particular lab, in addition to the requirements of the international quality standard for medical laboratories ISO 15189, widely known system: 5S, Lean manufacturing, 6 Sigma and others currently used effectively. To ensure successful implementation of the QMS and any other technology of the above, you first need will guide health organizations, the interest of the laboratory management and employee engagement as laboratories and medical organizations. The article discusses the role of the leader as well as intangible methods of motivation for effective personnel management.