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Potekaev N.N.

Moscow Scientific and Practical Center of Dermatovenerology and Cosmetology;
The Russian National Research Medical University named after N.I. Pirogov

Borzykh O.B.

Voyno-Yasenetsky Krasnoyarsk State Medical University (V.F. Voyno-Yasenetsky KrasSMU)

Shnayder N.A.

Bekhterev National Medical Research Center of Psychiatry and Neurology

Petrova M.M.

Voino-Yasenetsky Krasnoyarsk State Medical University

Karpova E.I.

Pirogov Russian National Research Medical University

Demina O.M.

Pirogov Russian National Research Medical University (RNRMU)

Zhukova O.V.

Moscow Research and Practical Center for Dermatovenereology and Cosmetology, Department of Healthcare;
Peoples’ Friendship University of Russia

Nasyrova R.F.

Bekhterev National Medical Research Center of Psychiatry and Neurology

Genomics of elastic fiber synthesis. Practical meaning for cosmetologists and dermatologists

Authors:

Potekaev N.N., Borzykh O.B., Shnayder N.A., Petrova M.M., Karpova E.I., Demina O.M., Zhukova O.V., Nasyrova R.F.

More about the authors

Journal: Russian Journal of Clinical Dermatology and Venereology. 2021;20(6): 52‑59

DOI: 10.17116/klinderma20212006152

Read: 5578 times

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Table of contents

GENOMICS OF ELASTIC FIBER SYNTHESIS. PRACTICAL MEANING FOR COSMETOLOGISTS AND DERMATOLOGISTS
GENOMICS OF ELASTIC FIBER SYNTHESIS. PRACTICAL MEANING FOR COSMETOLOGISTS AND DERMATOLOGISTS

To cite this article:

Potekaev NN, Borzykh OB, Shnayder NA, et al. . Genomics of elastic fiber synthesis. Practical meaning for cosmetologists and dermatologists. Russian Journal of Clinical Dermatology and Venereology. 2021;20(6):52‑59. (In Russ.)
https://doi.org/10.17116/klinderma20212006152

Подписка 2026 Клиническая дерматология и венерология (Russian Journal of Clinical Dermatology and Venereology)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The skin mechanical properties are realized mainly due to the extracellular matrix of the dermis consisting mostly of collagen and elastic fibers and hyaluronan (hyaluronic acid). Each of these components is responsible for different mechanical properties. In particular, elastic fibers are responsible for the skin elasticity (its ability to return to its original shape when stretched after tensile force end). If the function of elastic fibers is impaired the skin looks overstretched, loose and flabby.

It is known that the synthesis of extracellular matrix components is carried out by fibroblasts however the turnover of collagen and elastic fibers as well as hyaluronic acid has its own characteristics and factors that affect the turnover completeness.

OBJECTIVE

To analyze and systematize studies on elastic fibers’ synthesis in the skin as well as potential genes responsible for their turnover. This will help to better understand the complex multi-step process of assembly and degradation of elastic fibers as well as prepare a personalized approach to the management of patients by cosmetologists and dermatologists.

Keywords:

elastic fibers
elastin
genomics of elastic fibers
elastin assembly

Authors:

Potekaev N.N.

Moscow Scientific and Practical Center of Dermatovenerology and Cosmetology;
The Russian National Research Medical University named after N.I. Pirogov

Borzykh O.B.

Voyno-Yasenetsky Krasnoyarsk State Medical University (V.F. Voyno-Yasenetsky KrasSMU)

Shnayder N.A.

Bekhterev National Medical Research Center of Psychiatry and Neurology

Petrova M.M.

Voino-Yasenetsky Krasnoyarsk State Medical University

Karpova E.I.

Pirogov Russian National Research Medical University

Demina O.M.

Pirogov Russian National Research Medical University (RNRMU)

Zhukova O.V.

Moscow Research and Practical Center for Dermatovenereology and Cosmetology, Department of Healthcare;
Peoples’ Friendship University of Russia

Nasyrova R.F.

Bekhterev National Medical Research Center of Psychiatry and Neurology

Received:

09.03.2021

Accepted:

21.09.2021

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