Erosive and ulcerative lesions of gastrointestinal tract in patients with burns

Alekseev A.A.; Bobrovnikov A.E.

doi:https://doi.org/10.17116/hirurgia202012138

Alekseev A.A.

Vishnevsky National Medical Research Center for Surgery;
Russian Medical Academy for Continuous Professional Education

Bobrovnikov A.E.

Vishnevsky National Medical Research Center for Surgery;
Russian Medical Academy for Continuous Professional Education

Erosive and ulcerative lesions of gastrointestinal tract in patients with burns

Authors:

Alekseev A.A., Bobrovnikov A.E.

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Journal: Pirogov Russian Journal of Surgery. 2020;(12): 38‑45

DOI: 10.17116/hirurgia202012138

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To cite this article:

Alekseev AA, Bobrovnikov AE. Erosive and ulcerative lesions of gastrointestinal tract in patients with burns. Pirogov Russian Journal of Surgery. 2020;(12):38‑45. (In Russ.)
https://doi.org/10.17116/hirurgia202012138

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)

Использование инфографики авторами научных работ

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OBJECTIVE

To analyze the incidence of erosive and ulcerative lesions of gastrointestinal tract in patients with burns, including those complicated by gastrointestinal bleeding, depending on severity of injury, complications of burn disease and treatment features.

MATERIAL AND METHODS

Medical records of 1833 patients were reviewed. We have retrospectively analyzed symptoms of disease and incidence of gastrointestinal bleeding depending on treatment strategy in patients with identified erosive and ulcerative lesions of gastrointestinal tract.

RESULTS

Risk of gastrointestinal erosions and ulcers, including those complicated by gastrointestinal bleeding, correlates with area and depth of burn damage, especially in patients with thermo-inhalation injury and infectious complications of burn disease. Proton pump inhibitors intake in patients with burns of up to 50% of body surface area (BSA) and deep lesions up to 40% of BSA is followed by less incidence of gastrointestinal bleeding compared to H₂-histamine receptor blockers. At the same time, severe burns of more than 50% of BSA ensure high risk of gastrointestinal bleeding regardless antisecretory therapy.

CONCLUSION

Endoscopy upon admission is recommended in all patients with burns ≥30% of BSA or deep lesions ≥20% of BSA, as well as severe thermo-inhalation injury. This approach ensures timely diagnosis of gastrointestinal lesions and their adequate treatment.

Keywords:

burned patients

gastrointestinal erosion and ulcers

gastrointestinal bleeding

Authors:

Alekseev A.A.

Vishnevsky National Medical Research Center for Surgery;
Russian Medical Academy for Continuous Professional Education

Bobrovnikov A.E.

Vishnevsky National Medical Research Center for Surgery;
Russian Medical Academy for Continuous Professional Education

Received:

21.01.2020

Accepted:

11.02.2020

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