Methods of acute pancreatitis prevention after endoscopic transpapillary interventions

Beburishvili A.G.

Kafedra fakul'tetskoĭ khirurgii Volgogradskogo gosudarstvennogo meditsinskogo universiteta

Zyubina E.N.

Volgograd State Medical University, Department of Faculty Surgery with the course of endoscopic surgery and with the course of Cardiovascular Surgery, Faculty of Continuing Medical Education, Center for Surgical Hepatology

Turovets M.I.

Volgograd State Medical University, Volgograd scientific medical center, Volgograd, Russia

Mandrikov V.V.

Volgograd State Medical University, Volgograd scientific medical center, Volgograd, Russia

Methods of acute pancreatitis prevention after endoscopic transpapillary interventions

Authors:

Beburishvili A.G., Zyubina E.N., Turovets M.I., Mandrikov V.V.

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Journal: Pirogov Russian Journal of Surgery. 2015;(8): 35‑40

DOI: 10.17116/hirurgia2015835-40

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To cite this article:

Beburishvili AG, Zyubina EN, Turovets MI, Mandrikov VV. Methods of acute pancreatitis prevention after endoscopic transpapillary interventions. Pirogov Russian Journal of Surgery. 2015;(8):35‑40. (In Russ.)
https://doi.org/10.17116/hirurgia2015835-40

Подписка 2025 (Pirogov Russian Journal of Surgery)

Использование инфографики авторами научных работ

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Aim. To optimize preventive methods of acute postoperative pancreatitis in endoscopic transpapillary interventions. Material and methods. It is performed parallel unblinded randomized investigation. The first group included 98 patients who underwent endoscopic transpapillary interventions and thoracic epidural analgesia (TEA). The second group consisted of 97 patients in whom opiate analgesic intramuscularly and indomethacin per rectum were applied. Results. Study revealed that acute pancreatitis has been diagnosed significantly more seldom in patients after TEA than in the second group (OR 0.22, CI 95%, 0.06-0.83). Thus in TEA-group pancreatitis was verified in 3.1% (3 of 98 patients), in the second group - in 12.4% (12 of 97 patients). Incidence of pancreatitis decreased from 23.3% (10 of 43) to 4.3% (2 of 46) among high risk patients (OR 0.15, 95% CI 0.03-0.75). Conclusion. TEA is effective and justified preventive method in patients with high risk of postoperative pancreatitis. In low risk patients use of indomethacin per rectum is preferred compared with TEA due to its invasiveness.

Keywords:

endoscopic transpapillary intervention

thoracic epidural analgesia

prevention of acute postoperative pancreatitis

Authors:

Beburishvili A.G.

Kafedra fakul'tetskoĭ khirurgii Volgogradskogo gosudarstvennogo meditsinskogo universiteta

Zyubina E.N.

Turovets M.I.

Volgograd State Medical University, Volgograd scientific medical center, Volgograd, Russia

Mandrikov V.V.

Volgograd State Medical University, Volgograd scientific medical center, Volgograd, Russia

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