The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Filippov A.A.

Almazov National Medical Research Centre;
Saint-Petersburg State University

Shcherbinin T.S.

Almazov National Medical Research Centre

Kim G.I.

Saint-Petersburg State University

Zavarzina D.G.

Almazov National Medical Research Centre

Ryadinskii M.E.

Saint-Petersburg State University

Tolpygin D.S.

Almazov National Medical Research Centre

Malashicheva A.B.

Almazov National Medical Research Centre

Gordeev M.L.

Almazov National Medical Research Center

Ascending aortic dilation after aortic valve replacement depending on phenotype of bicuspid aortic valve in patients with borderline dilation of ascending aorta

Authors:

Filippov A.A., Shcherbinin T.S., Kim G.I., Zavarzina D.G., Ryadinskii M.E., Tolpygin D.S., Malashicheva A.B., Gordeev M.L.

More about the authors

Journal: Russian Journal of Cardiology and Cardiovascular Surgery. 2025;18(1): 79‑85

DOI: 10.17116/kardio20251801179

Read: 812 times

Buy for 300₽
Contact the author
Table of contents

ASCENDING AORTIC DILATION AFTER AORTIC VALVE REPLACEMENT DEPENDING ON PHENOTYPE OF BICUSPID AORTIC VALVE IN PATIENTS WITH BORDERLINE DILATION OF ASCENDING AORTA
ASCENDING AORTIC DILATION AFTER AORTIC VALVE REPLACEMENT DEPENDING ON PHENOTYPE OF BICUSPID AORTIC VALVE IN PATIENTS WITH BORDERLINE DILATION OF ASCENDING AORTA

To cite this article:

Filippov AA, Shcherbinin TS, Kim GI, et al. . Ascending aortic dilation after aortic valve replacement depending on phenotype of bicuspid aortic valve in patients with borderline dilation of ascending aorta. Russian Journal of Cardiology and Cardiovascular Surgery. 2025;18(1):79‑85. (In Russ.)
https://doi.org/10.17116/kardio20251801179

ЭндоКард
Подписка 2026 Кардиология и сердечно-сосудистая хирургия (Russian Journal of Cardiology and Cardiovascular Surgery)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
Recommended articles:
Long-term resu­lts of aortic valve replacement in patients with severe left ventricular dysfunction. Russian Journal of Cardiology and Cardiovascular Surgery. 2024;(6):609-616
Imme­diate and mid-term resu­lts of the Ross and Ozaki procedures in adults. Russian Journal of Cardiology and Cardiovascular Surgery. 2025;(2):127-134
Sele­ction of opti­mal aortotomy in various cardiac surgeries. Russian Journal of Cardiology and Cardiovascular Surgery. 2025;(3):306-309
Septal myectomy in aortic valve replacement for severe aortic stenosis. Russian Journal of Cardiology and Cardiovascular Surgery. 2025;(3):326-334
Adapted scale for analysis of nece­ssary septal myectomy in aortic valve replacement. Piro­gov Russian Journal of Surgery. 2024;(12-2):35-41
Intraoperative left ventricular rupture in cardiac surgery. Piro­gov Russian Journal of Surgery. 2025;(4):95-99
Cognitive impairment after major surgical operations. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(4-2):74-80
Abstract:

OBJECTIVE

To analyze ascending aorta dilation depending on phenotypes of bicuspid aortic valve (BAV) within 12 months after aortic valve replacement (AVR).

MATERIAL AND METHODS

A study with two parallel groups included 79 patients with BAV and dilation of the ascending aorta to 45—50 mm who underwent AVR between January 2018 and June 2022. The 1st group (BAV-AP) included 46 patients with anteroposterior orientation of leaflets (RL phenotype and true BAV), the 2nd group (BAV-RL) — 33 patients with right-left orientation of leaflets (RN phenotype, LN phenotype and true BAV with coronary arteries arising from different sinuses of Valsalva). In preoperative and follow-up period (12 months after surgery), all patients underwent transthoracic echocardiography to assess diameter of the ascending aorta.

RESULTS

In the 1st group, diameter of the ascending aorta increased in 13 (39.4%) patients by 0.72 mm (p=0.001) and by 0.39 mm in 6 (13.0%) patients in the 2nd group (p=0.013). There was no significant dilatation of sinuses of Valsalva in both groups.

CONCLUSION

Ascending aorta dilation after AVR was observed in patients with BAV-AP and BAV-RL phenotypes. There was slightly faster enlargement of ascending aorta in many patients with BAV-RL phenotype.

Keywords:

bicuspid aortic valve
ascending aortic aneurysm
sinuses of Valsalva
aortic valve replacement

Authors:

Filippov A.A.

Almazov National Medical Research Centre;
Saint-Petersburg State University

Shcherbinin T.S.

Almazov National Medical Research Centre

Kim G.I.

Saint-Petersburg State University

Zavarzina D.G.

Almazov National Medical Research Centre

Ryadinskii M.E.

Saint-Petersburg State University

Tolpygin D.S.

Almazov National Medical Research Centre

Malashicheva A.B.

Almazov National Medical Research Centre

Gordeev M.L.

Almazov National Medical Research Center

Received:

15.12.2023

Accepted:

10.07.2024

Close metadata

References:

  1. Bray JJH, Freer R, Pitcher A, Kharbanda R. Family screening for bicuspid aortic valve and aortic dilatation: a meta-analysis. Eur Heart J. 2023;44(33):3152-3164. https://doi.org/10.1093/eurheartj/ehad320
  2. Sievers HH, Sievers HL. Aortopathy in bicuspid aortic valve disease — genes or hemodynamics? or Scylla and Charybdis? Eur J Cardiothorac Surg. 2011;39:803-804.  https://doi.org/10.1016/j.ejcts.2011.02.007
  3. Capoulade R, Schott JJ, Le Tourneau T. Familial bicuspid aortic valve disease: should we look more closely at the valve? Heart. 2019;105(8):584-586.  https://doi.org/10.1136/heartjnl-2018-314063
  4. Geeraert P, Jamalidinan F, Burns F, et al. Hemodynamic Assessment in Bicuspid Aortic Valve Disease and Aortic Dilation: New Insights From Voxel-By-Voxel Analysis of Reverse Flow, Stasis, and Energetics. Frontiers in Bioengineering and Biotechnology. 2022;9.  https://doi.org/10.3389/fbioe.2021.725113
  5. Hanigk M, Burgstaller E, Latus H, et al. Aortic wall shear stress in bicuspid aortic valve disease-10-year follow-up. Cardiovasc Diagn Ther. 2023;13(1):38-50.  https://doi.org/10.21037/cdt-22-477
  6. Kalinowski ME, Szulik M, Pawlak S, et al. The impact of the aortic cusps fusion pattern and valve disease severity on the aortic wall mechanics in patients with bicuspid aortic valve. The International Journal of Cardiovascular Imaging. 2020;36(8):1429-1436. https://doi.org/10.1007/s10554-020-01838-0
  7. Sievers H-H, Schmidtke C. A classification system for the bicuspid aortic valve from 304 surgical specimens. The Journal of Thoracic and Cardiovascular Surgery. 2007;33(5):1226-1233. https://doi.org/10.1016/j.jtcvs.2007.01.039
  8. Salerno M, Chandrashekhar Y. CMR 4D-Flow Wall Shear Stress and Aortic Dilation in Bicuspid Aortic Valve. JACC: Cardiovascular Imaging. 2022;15(1):177-179.  https://doi.org/10.1016/j.jcmg.2021.12.001
  9. Parker MW, Muchnik RD, Ogunsua A, et al. Serial echocardiography for valve dysfunction and aortic dilation in bicuspid aortic valves. Echocardiography. 2021;38(3):394-401.  https://doi.org/10.1111/echo.15000
  10. Schaefer BM, Lewin MB, Stout KK, et al. Usefulness of Bicuspid Aortic Valve Phenotype to Predict Elastic Properties of the Ascending Aorta. The American Journal of Cardiology. 2007;99(5):686-690.  https://doi.org/10.1016/j.amjcard.2006.09.118
  11. Buchner S, Hulsmann M, Poschenrieder F, et al. Variable phenotypes of bicuspid aortic valve disease: classification by cardiovascular magnetic resonance. Heart. 2010;96(15):1233-1240. https://doi.org/10.1136/hrt.2009.186254
  12. Ruzmetov M, Shah JJ, Fortuna RS, Welke KF. The Association Between Aortic Valve Leaflet Morphology and Patterns of Aortic Dilation in Patients With Bicuspid Aortic Valves. The Annals of Thoracic Surgery. 2015;99(6):2101-2108. https://doi.org/10.1016/j.athoracsur.2015.02.036
  13. Granath C, Mohamed SA, Olsson C, et al. Valve disease and aortopathy associations of bicuspid aortic valve phenotypes differ between men and women. Open Heart. 2021;8(2):e001857. https://doi.org/10.1136/openhrt-2021-001857
  14. Rodríguez-Palomares JF, Dux-Santoy L, Guala A, et al. Mechanisms of Aortic Dilation in Patients With Bicuspid Aortic Valve: JACC State-of-the-Art Review. J Am Coll Cardiol. 2023;82(5):448-464.  https://doi.org/10.1016/j.jacc.2022.10.042
  15. Rodríguez-Palomares JF, Dux-Santoy L, Guala A, et al. Aortic flow patterns and wall shear stress maps by 4D-flow cardiovascular magnetic resonance in the assessment of aortic dilatation in bicuspid aortic valve disease. Journal of Cardiovascular Magnetic Resonance. 2018;20(1). https://doi.org/10.1186/s12968-018-0451-1
  16. Oliveira D, Rosa SA, Tiago J, et al. Bicuspid aortic valve aortopathies: An hemodynamics characterization in dilated aortas. Computer Methods in Biomechanics and Biomedical Engineering. 2019;22(8):815-826.  https://doi.org/10.1080/10255842.2019.1597860
  17. Charitos E, Stierle U, Hanke T, et al. The fate of bicuspid valve aortopathy after aortic valve replacement. Interactive CardioVascular and Thoracic Surgery. 2013;17(suppl 2):S123-S123. https://doi.org/10.1093/icvts/ivt372.222
  18. Regeer MV, Versteegh MIM, Klautz RJM, et al. Effect of Aortic Valve Replacement on Aortic Root Dilatation Rate in Patients With Bicuspid and Tricuspid Aortic Valves. The Annals of Thoracic Surgery. 2016;102(6):1981-1987. https://doi.org/10.1016/j.athoracsur.2016.05.038
  19. Messner B, Bernhard D. Bicuspid aortic valve-associated aortopathy: Where do we stand? Journal of Molecular and Cellular Cardiology. 2019;133:76-85.  https://doi.org/10.1016/j.yjmcc.2019.05.023
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.