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Filippov A.A.

Almazov National Medical Research Centre;
Saint-Petersburg State University

Shcherbinin T.S.

Almazov National Medical Research Centre

Kim G.I.

Saint-Petersburg State University

Zavarzina D.G.

Almazov National Medical Research Centre

Ryadinskii M.E.

Saint-Petersburg State University

Tolpygin D.S.

Almazov National Medical Research Centre

Malashicheva A.B.

Almazov National Medical Research Centre

Gordeev M.L.

Almazov National Medical Research Center

Ascending aortic dilation after aortic valve replacement depending on phenotype of bicuspid aortic valve in patients with borderline dilation of ascending aorta

Authors:

Filippov A.A., Shcherbinin T.S., Kim G.I., Zavarzina D.G., Ryadinskii M.E., Tolpygin D.S., Malashicheva A.B., Gordeev M.L.

More about the authors

Journal: Russian Journal of Cardiology and Cardiovascular Surgery. 2025;18(1): 79‑85

DOI: 10.17116/kardio20251801179

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Table of contents

ASCENDING AORTIC DILATION AFTER AORTIC VALVE REPLACEMENT DEPENDING ON PHENOTYPE OF BICUSPID AORTIC VALVE IN PATIENTS WITH BORDERLINE DILATION OF ASCENDING AORTA
ASCENDING AORTIC DILATION AFTER AORTIC VALVE REPLACEMENT DEPENDING ON PHENOTYPE OF BICUSPID AORTIC VALVE IN PATIENTS WITH BORDERLINE DILATION OF ASCENDING AORTA

To cite this article:

Filippov AA, Shcherbinin TS, Kim GI, et al. . Ascending aortic dilation after aortic valve replacement depending on phenotype of bicuspid aortic valve in patients with borderline dilation of ascending aorta. Russian Journal of Cardiology and Cardiovascular Surgery. 2025;18(1):79‑85. (In Russ.)
https://doi.org/10.17116/kardio20251801179

Подписка 2025-2 (Russian Journal of Cardiology and Cardiovascular Surgery)
 
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OBJECTIVE

To analyze ascending aorta dilation depending on phenotypes of bicuspid aortic valve (BAV) within 12 months after aortic valve replacement (AVR).

MATERIAL AND METHODS

A study with two parallel groups included 79 patients with BAV and dilation of the ascending aorta to 45—50 mm who underwent AVR between January 2018 and June 2022. The 1st group (BAV-AP) included 46 patients with anteroposterior orientation of leaflets (RL phenotype and true BAV), the 2nd group (BAV-RL) — 33 patients with right-left orientation of leaflets (RN phenotype, LN phenotype and true BAV with coronary arteries arising from different sinuses of Valsalva). In preoperative and follow-up period (12 months after surgery), all patients underwent transthoracic echocardiography to assess diameter of the ascending aorta.

RESULTS

In the 1st group, diameter of the ascending aorta increased in 13 (39.4%) patients by 0.72 mm (p=0.001) and by 0.39 mm in 6 (13.0%) patients in the 2nd group (p=0.013). There was no significant dilatation of sinuses of Valsalva in both groups.

CONCLUSION

Ascending aorta dilation after AVR was observed in patients with BAV-AP and BAV-RL phenotypes. There was slightly faster enlargement of ascending aorta in many patients with BAV-RL phenotype.

Keywords:

bicuspid aortic valve
ascending aortic aneurysm
sinuses of Valsalva
aortic valve replacement

Authors:

Filippov A.A.

Almazov National Medical Research Centre;
Saint-Petersburg State University

Shcherbinin T.S.

Almazov National Medical Research Centre

Kim G.I.

Saint-Petersburg State University

Zavarzina D.G.

Almazov National Medical Research Centre

Ryadinskii M.E.

Saint-Petersburg State University

Tolpygin D.S.

Almazov National Medical Research Centre

Malashicheva A.B.

Almazov National Medical Research Centre

Gordeev M.L.

Almazov National Medical Research Center

Received:

15.12.2023

Accepted:

10.07.2024

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