The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2026
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Lysenko A.V.

Petrovsky Russian Scientific Center of Surgery

Belov Yu.V.

Petrovsky National Research Center of Surgery;
Sechenov First Moscow State Medical University

Dzeranova A.N.

Petrovsky National Research Center of Surgery

Lednev P.V.

Petrovsky Russian Scientific Center of Surgery

Nikityuk T.G.

Petrovsky National Research Center of Surgery

Salagaev G.I.

Petrovsky Russian Scientific Center of Surgery

Mitral valve disjunction in patients with myxomatous degeneration and severe mitral regurgitation

Authors:

Lysenko A.V., Belov Yu.V., Dzeranova A.N., Lednev P.V., Nikityuk T.G., Salagaev G.I.

More about the authors

Journal: Russian Journal of Cardiology and Cardiovascular Surgery. 2024;17(1): 102‑106

DOI: 10.17116/kardio202417011102

Read: 6133 times

Contact the author
Table of contents

MITRAL VALVE DISJUNCTION IN PATIENTS WITH MYXOMATOUS DEGENERATION AND SEVERE MITRAL REGURGITATION
MITRAL VALVE DISJUNCTION IN PATIENTS WITH MYXOMATOUS DEGENERATION AND SEVERE MITRAL REGURGITATION

To cite this article:

Lysenko AV, Belov YuV, Dzeranova AN, Lednev PV, Nikityuk TG, Salagaev GI. Mitral valve disjunction in patients with myxomatous degeneration and severe mitral regurgitation. Russian Journal of Cardiology and Cardiovascular Surgery. 2024;17(1):102‑106. (In Russ.)
https://doi.org/10.17116/kardio202417011102

Подписка 2026 Кардиология и сердечно-сосудистая хирургия (Russian Journal of Cardiology and Cardiovascular Surgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
Clinical features of myocardial infa­rction in young patients. Part 2. Predictors of sudden cardiac death and recu­rrent cardiovascular events. Russian Journal of Preventive Medi­cine. 2025;(10):60-66
Moni­toring of chro­nic heart failure using transthoracic impe­dance and heart rate variability sensor in patients with cardioverter defi­brillator. Russian Cardiology Bulletin. 2025;(4):48-55
Dyna­mics of sudden death rates from diseases of the circulatory system in St. Pete­rsburg in 2007—2021 acco­rding to the Bureau of Fore­nsic Medi­cal Examination. Fore­nsic Medi­cal Expe­rtise. 2026;(1):11-15
Practical reco­mmendations for the sudden cardiac death prevention among vehi­cle drivers. Russian Journal of Preventive Medi­cine. 2026;(3):86-93
Abstract:

Mitral valve disjunction is a specific anatomical anomaly associated with mitral valve prolapse and characterized by separation of mitral annulus and left atrium wall from basal posterolateral LV wall. The authors present surgical treatment of 2 patients with myxomatous degeneration and mitral valve disjunction, whose postoperative period was complicated by severe heart rhythm disturbances.

Keywords:

mitral valve disjunction
mitral valve prolapse
ventricular fibrillation
sudden cardiac death

Authors:

Lysenko A.V.

Petrovsky Russian Scientific Center of Surgery

Belov Yu.V.

Petrovsky National Research Center of Surgery;
Sechenov First Moscow State Medical University

Dzeranova A.N.

Petrovsky National Research Center of Surgery

Lednev P.V.

Petrovsky Russian Scientific Center of Surgery

Nikityuk T.G.

Petrovsky National Research Center of Surgery

Salagaev G.I.

Petrovsky Russian Scientific Center of Surgery

Received:

10.09.2023

Accepted:

29.09.2023

Close metadata

References:

  1. Freed LA, Levy D, Levine RA, Larson MG, Evans JC, Fuller DL, et al. Prevalence and clinical outcome of mitral-valve prolapse. N Engl J Med. 1999;341(1):1-7.  https://doi.org/10.1056/NEJM199907013410101
  2. Dziadzko V, Dziadzko M, Medina-Inojosa JR, Benfari G, Michelena HI, Crestanello JA, et al. Causes and mechanisms of isolated mitral regurgitation in the community: clinical context and outcome. Eur Heart J. 2019;40(27):2194-2202. https://doi.org/10.1093/eurheartj/ehz314
  3. Konda T, Tani T, Suganuma N, Nakamura H, Sumida T, Fujii Y, et al. The analysis of mitral annular disjunction detected by echocardiography and comparison with previously reported pathological data. J Echocardiogr. 2017;15(4):176-185.  https://doi.org/10.1007/s12574-017-0349-1
  4. Carmo P, Andrade MJ, Aguiar C, Rodrigues R, Gouveia R, Silva JA. Mitral annular disjunction in myxomatous mitral valve disease: a relevant abnormality recognizable by transthoracic echocardiography. Cardiovasc Ultrasound. 2010;8:53.  https://doi.org/10.1186/1476-7120-8-53
  5. Eriksson MJ, Bitkover CY, Omran AS, David TE, Ivanov J, Ali MJ, et al. Mitral annular disjunction in advanced myxomatous mitral valve disease: echocardiographic detection and surgical correction. J Am Soc Echocardiogr. 2005;18(10):1014-1022. https://doi.org/10.1016/j.echo.2005.06.013
  6. Hutchins GM, Moore GW, Skoog DK. The association of floppy mitral valve with disjunction of the mitral annulus fibrosis. N Engl J Med. 1986;535-540. 
  7. Basso C, Perazzolo Marra M, Rizzo S, De Lazzari M, Giorgi B, Cipriani A, et al. Arrhythmic mitral valve prolapse and sudden cardiac death. Circulation. 2015;132(7):556-566.  https://doi.org/10.1161/CIRCULATIONAHA.115.016291
  8. Essayagh B, Sabbag A, Antoine C, Benfari G, Batista R, Yang LT, et al. The mitral annular disjunction of mitral valve prolapse: presentation and outcome. JACC Cardiovasc Imaging. 2021;14(11):2073-2087. https://doi.org/10.1016/j.jcmg.2021.04.029
  9. Mantegazza V, Tamborini G, Muratori M, Gripari P, Fusini L, Italiano G, et al. Mitral annular disjunction in a large cohort of patients with mitral valve prolapse and significant regurgitation. JACC Cardiovasc Imaging. 2019;12(11 Pt 1):2278-2280. https://doi.org/10.1016/j.jcmg.2019.06.021
  10. Dejgaard LA, Skjølsvik ET, Lie ØH, Ribe M, Stokke MK, Hegbom F, et al. The mitral annulus disjunction arrhythmic syndrome. J Am Coll Cardiol. 2018;72(14):1600-1609. https://doi.org/10.1016/j.jacc.2018.07.070
  11. Newcomb AE, David TE, Lad VS, et al. Mitral valve repair for advanced myxomatous degeneration with posterior displacement of the mitral annulus. J Thorac Cardiovasc Surg. 2008;136:1503-1509.
  12. Lee AP, Jin CN, Fan Y, et al. Functional Implication of mitral annular disjunction in mitral valve prolapse: A quantitative dynamic 3D echocardiographic study. Jacc Cardiovasc Imaging. 2017;10:1424-1433.
  13. Chivulescu M, Krohg-Sørensen K, Scheirlynck E, Lindberg BR, Dejgaard LA, Lie ØH, et al. Mitral annulus disjunction is associated with adverse outcome in Marfan and Loeys—Dietz syndromes. Eur Heart J Cardiovasc Imaging. 2021;22(9):1035-1044. https://doi.org/10.1093/ehjci/jeaa324
  14. Essayagh B, Iacuzio L, Civaia F, Avierinos JF, Tribouilloy C, Levy F. Usefulness of 3-Tesla cardiac magnetic resonance to detect mitral annular disjunction in patients with mitral valve prolapse. Am J Cardiol. 2019;124(11):1725-1730. https://doi.org/10.1016/j.amjcard.2019.08.047
  15. Niarchou P, Prappa E, Liatakis I, Vlachos K, Chatziantoniou A, Nyktari E, et al. Mitral valve prolapse and mitral annular disjunction arrhythmic syndromes: diagnosis, risk stratification and management. Rev Cardiovasc Med. 2022;23(9):295.  https://doi.org/10.31083/j.rcm2309295
  16. Faletra FF, Leo LA, Paiocchi VL, Schlossbauer SA, Pavon AG, Ho SY, et al. Morphology of mitral annular disjunction in mitral valve prolapse. J Am Soc Echocardiogr. 2022;35(2):176-186.  https://doi.org/10.1016/j.echo.2021.09.002
  17. Suri RM, Vanoverschelde JL, Grigioni F, et al. Association between early surgical intervention vs watchful waiting and outcomes for mitral regurgitation due to flail mitral valve leaflets. JAMA. 2013;310:609-616. 
  18. Komoda T, Hetzer R, Oellinger J, et al. Mitral annular flexibility. J Card Surg. 1997;12:102-109. 
  19. Nistri S, Galderisi M, Ballo P, et al. Determinants of echocardiographic left atrial volume: Implications for normalcy. Eur J Echocardiogr J Work Group Echocardiogr Eur Soc Cardiol. 2011;12:826-833. 
  20. Topilsky Y, Vaturi O, Watanabe N, et al. Real-time 3-dimensional dynamics of functional mitral regurgitation: A prospective quantitative and mechanistic study. J Am Heart Assoc. 2013;2:e000039.
  21. Bennett S, Thamman R, Griffiths T, et al. Mitral annular disjunction: A systematic review of the literature. Echocardiography. 2019;36:1549-1558.
  22. VanWijngaarden AL, de Riva M, Hiemstra YL, et al. Parameters associated with ventricular arrhythmias in mitral valve prolapse with significant regurgitation. Heart. 2020.
  23. Baumgartner H, Falk V, Bax JJ, et al. 2017 ESC/EACTS Guidelines for the management of valvular heart disease. Eur Heart J. 2017;38:2739-2791.
  24. Nishimura RA, Otto CM, Bonow RO, et al. 2017 AHA/ACC focused update of the 2014 AHA/ACC guideline for the management of patients with valvular heart disease: A report of the american college of cardiology/American heart association task force on clinical practice guidelines. Circulation. 2017;135:e1159.
  25. David TE, David CM, Tsang W, et al. Long-term results of mitral valve repair for regurgitation due to leaflet prolapse. J Am Coll Cardiol. 2019;74:1044-1053.
  26. Lysenko AV, Salagaev GI, Lednev PV, Magomedova GF, Belov YuV. Septal myectomy combined with mitral valve repair in a patient with diffuse form of obstructive hypertrophic cardiomyopathy. Kardiologiya i Serdechno-Sosudistaya Khirurgiya. 2023;16(3):321-325. (In Russ.). https://doi.org/10.17116/kardio202316031321
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.