OBJECTIVE
To study the main parameters of preimplantation screening and optimize selection of patients for implantation of a subcutaneous cardioverter-defibrillator (ICD).
MATERIAL AND METHODS
In 91 patients with indications for implantation of a subcutaneous ICD, preimplantation screening was performed to determine the possibility of correct perception of subcutaneous signal and reduce the risk of inappropriate discharge. Patients were eligible for ICD implantation if at least one suitable vector was available. We analyzed anthropometric characteristics (height, weight, body mass index), echocardiography and ECG parameters (left ventricular ejection fraction, left ventricular end-systolic dimension, end-diastolic dimension, end-systolic volume and end-diastolic volume and QRS duration as potential predictors of preimplantation screening failure.
RESULTS
Among 91 patients, screening failure was identified in 9 patients (9.8%) and these ones underwent implantation of transvenous ICD. We observed significant between-group differences in patient height (174 [170; 178] vs. 180 [175; 183] cm, p=0.01) and QRS duration (100 [94; 108] vs. 119 [114; 136] ms, p=0.0003). Echocardiography data were similar in patients with successful and failed screening.
CONCLUSION
Currently available preimplantation screening algorithms recommended by the manufacturer are associated with a significant incidence of failures. Possible predictors of a negative result of preimplantation screening of candidates for subcutaneous ICD implantation are non-standard anthropometric parameters of patients. Introduction of new opportunities for prevention of sudden cardiac death is an important and urgent objective of modern cardiology.