Aim — the objective of the present study was to demonstrate the therapeutic potential of the endovascular and endoscopic techniques employed for the treatment of the pelvic congestion syndrome caused by the May—Thurner syndrome in conjunction with the syndrome of the right gonadal vein. Material and methods. A 37 year old female patient presented with the clinical signs of pelvic congestion syndrome (PCS). This condition was confirmed by the results of computed tomography, ovaricography, and pelvic venography; simultaneously, May—Thurner and right ovarian vein syndromes were diagnosed. The compression of the right ureter by the gonadal vein was accompanied by the phenomenon of right ureter obstruction. Results. The first stage of the treatment consisted of endovascular stenting of the left iliac veins. It was followed by the retroperitoneal endoscopic resection of the right gonadal vein. The final stage was reduced to endoscopic stenting of the right ureter. The combination of these intervention made it possible to restore the patency of the left common iliac vein, reduce the severity of the symptoms of PCS, and to eliminate right ureter obstruction. The analysis of the relevant medical literature concerning the treatment of the May—Thurner syndrome, PCS, and right ovarian vein syndrome was carried out. Conclusions. The pelvic congestion syndrome can be combined with stenosis of the left common iliac vein and the syndrome of the right gonadal vein. Adequate investigation of pelvic veins and the urinary track system together with the step-by-step application of the endovascular techniques can effectively reverse the signs and symptoms of the pelvic congestion syndrome and normalize the passage of urine in the ureters.